Herbicidal pyridinesulfonylureas

ABSTRACT

This invention relates to herbicidal pyridinesulfonylureas which are highly active as preemergence and postemergence herbicides.

This application is a division of prior copending application Ser. No.07/507,926, filed Apr. 12, 1990, now granted as U.S. Pat. No. 5,102,444,granted Apr. 7, 1992; which is in turn a continuation-in-part ofcopending application Ser. No. 399,485, filed May 26, 1989, nowabandoned; which in turn derives from PCT application Ser. No.US87/03111, filed Dec. 4, 1987; which in turn was a continuation-in-partof copending U.S. application Ser. No. 07/039,491, filed Apr. 16, 1987,now abandoned; which in turn was a continuation-in-part of copendingapplication Ser. No. 939,428, filed Dec. 8, 1985, now abandoned.

BACKGROUND OF THE INVENTION

Pyridinesulfonylureas of the instant application show high activity aspreemergence and postemergence herbicides. In particular, safety to cornis demonstrated by many of the herbicides.

EP-A-13,480 discloses herbicidal sulfonamides of the formula ##STR1##wherein

R₁ is H, Cl, Br, F, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ alkylthio, NO₂or CO₂ R₅.

U.S. Pat. No. 4,435,206, issued Mar. 6, 1984 and U.S. Pat. No.4,522,645, issued Jun. 11, 1985, disclose 2-pyridinesulfonylureassubstituted in the 3-position by R₁, wherein R₁ is H, Cl, Br, F, C₁ -C₄alkyl, C₁ -C₄ alkoxy, C₁ -C₄ alkylthio, NO₂, CF₃, CO₂ R₅ or SO₂ NR₆ R₇.

U.S. Pat. No. 4,339,267 discloses herbicidal sulfonamides of the formula##STR2## wherein R₄ is H, Cl, Br, F, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, NO₂,CO₂ R₆ or SR₁₃.

EP-A-30,433 discloses herbicidal sulfonamides of the formula ##STR3##wherein X is H;

R₁₄ is H or CH₃ ; and

R₃ is H, F, Cl, Br, CH₃, OCH₃, NO₂, CO₂ R₁₁ or S(O)_(n) R₁₂.

U.S. Pat. No. 4,456,469 discloses herbicidal sulfonamides of the formula##STR4## wherein R is C₁ -C₆ alkyl, C₃ -C₆ alkenyl, C₂ -C₄ alkoxyalkyl,C₅ -C₆ cycloalkyl, R'OCH₂ CH₂ OCH₂, R'OCH₂ CH₂ OCH₂ CH₂, ##STR5## CF₃,CF₃ CH₂, HGLCCF₂ or HCF₂ ; and Z is H, F, Cl, Br, CH₃, OCH₃ or SCH₃.

U.S. Pat. No. 4,487,626 discloses herbicidal sulfonamides of the formula##STR6## wherein ##STR7## and R₂ is H, F, Cl, Br, C₁ -C₄ alkyl, C₁ -C₄alkoxy, NO₂, CO₂ R₁₅, S(O)_(m) R₁₆, SO₂ NR₁₈ R₁₉ or SO₂ N(OCH₃)CH₃.

U.S. Pat. No. 4,421,550 discloses herbicidal sulfonamides of the formula##STR8## wherein z is ##STR9## and R₁₆ is H, C₁ -C₄ alkyl, C₁ -C₄alkoxy, F, Cl, Br, CF₃, CO₂ R₂₀, SO₂ NR₁₀ R₁₁, SO₂ N(OCH₃)CH₃ orS(O)_(n) R₁₃.

U.S. Pat. No. 4,496,392 discloses herbicidal sulfonamides of the formula##STR10## wherein R₃ is Cl, SO₂ CH₃ or SO₂ N(CH₃)₂.

EP-A-84,224 discloses herbicidal sulfonamides of the formula ##STR11##wherein A is ##STR12## and R₁₆ is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, F, Cl,Br, CF₃, CO₂ R₉, SO₂ NR₁₀ R₁₁, SO₂ N(OCH₃)CH₃ or S(O)_(n) R₁₃.

EP-A-125,846 discloses herbicidal sulfonamides of the formula ##STR13##wherein J is ##STR14## and R₃ is Cl, SO₂ CH₃, SO₂ N(CH₃)₂, OCH₃, NO₂ orN(CH₃)₂.

EP-A-155,767 disclose herbicidal sulfonamides of the formula ##STR15##wherein J is ##STR16## and R₅ is H, CH₃, Cl, Br, CO₂ R₁₅, C(O)NR₁₆ R₁₇,SO₂ NR₁₆ R₁₇, SO₂ N(OCH₃)CH₃, SO₂ R₁₈ or NO₂.

EP-A-161,905 discloses herbicidal sulfonamides of the formula ##STR17##wherein R₄ is CH₃, CH₂ CH₃, OCH₃, OCH₂ CH₃, F, Cl, Br, SO₂ NR₁₆ R₁₇, SO₂N(OCH₃)CH₃, S(O)_(n) R₁₉, C₃ -C₄ alkenyloxy or C₃ -C₄ alkynyloxy.

EP-A-164,269 discloses herbicidal sulfonamides of the formula ##STR18##wherein R₄ is CH₃, CH₂ CH₃, OCH₃, OCH₂ CH₃, F, Cl, Br, SO₂ NR₁₁ R₁₂, SO₂N(OCH₃)CH₃ or S(O)_(n) R₁₃.

EP-A-171,286 discloses herbicidal sulfonamides of the formula ##STR19##wherein R₄ is CH₃, CH₂ CH₃, OCH₃, OCH₂ CH₃, F, Cl, Br, SO₂ NR₁₈ R₁₉, SO₂N(OCH₃)CH₃, S(O)_(n) R₂₁, C₃ -C₄ alkenyloxy, CH₂ OCH₃ or CH₂ OCH₂ CH₃.

South African Patent Application 83/4305, published Dec. 14, 1983,discloses herbicidal sulfonamides of the formula ##STR20## wherein R₂ isH, C₁ -C₃ alkyl, C₁ -C₃ haloalkyl, halogen, NO₂, C₁ -C₃ alkoxy, C(W)R₈,SO₂ NR₆ R₇, S(O)_(n) C₁ -C₃ alkyl or C(O)R₉ ;

R₃ is H, halogen, C₁ -C₃ alkyl, OCH₃, NO₂ or CF₃ ;

R₅ is H, NO₂, F, Cl, Br, CH₃, CF₃, S(O)_(n) C₁ -C₃ alkyl, C(O)C₁ -C₄alkoxy or C₁ -C₃ alkoxy;

Y is O or S.

South African Patent Application 83/6639, published Mar. 8, 1984,discloses herbicidal sulfonamides of the formula ##STR21## wherein A isa C₃ -C₆ alkynyl radical, a C₁ -C₆ alkyl radical which is substituted byhalogen, C₁ -C₄ alkoxy, C₁ -C₄ alkylthio, C₁ -C₄ alkylsulfinyl, C₁ -C₄alkylsulfonyl, C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkylthio, C₁ -C₄haloalkylsulfinyl or C₁ -C₄ haloalkylsulfonyl, or is a C₂ -C₄ alkenylradical which is unsubstituted or substituted as for C₁ -C₆ alkyl, or isa phenyl radical which is unsubstituted or substituted by halogen,cyano, nitro, C₁ -C₄ alkyl, C₁ -C₄ haloalkyl, an --X--C₁ -C₄ alkyl, C₁-C₄ alkoxycarbonyl, amino, mono- or di(C₁ -C₄ alkyl)amino, carbamoyl,mono- or di-(C₁ -C₄ alkyl)carbamoyl, sulfamoyl, mono- or di-(C₁ -C₄alkyl)sulfamoyl radical;

R₁ is hydrogen, halogen, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkyl,C₁ -C₄ haloalkoxy, C₂ -C₅ alkoxyalkoxy, C₁ -C₅ alkylthio, C₁ -C₅alkylsulfinyl or C₁ -C₅ alkylsulfonyl; and

X is O, S, SO or SO₂.

U.S. Pat. No. 4,518,776 discloses a process for the preparation ofherbicidal sulfonamides of the formula ##STR22## wherein R₁, in part, isS(O)_(n) C₁ -C₄ alkyl, SO₂ di-C₁ -C₄ alkylamino or CO₂ --C₁ -C₂ alkyl:and

R₂ is H, halogen, CF₃, NO₂, C₁ -C₄ alkyl or C₁ -C₄ alkoxy.

This Patent generically discloses some, but does not claim any,compounds of the instant invention.

EP-A-101,670, published Feb. 29, 1984, discloses a process for thepreparation of herbicidal sulfonamides of the formula ##STR23## whereinR₁ is Q--C₁ -C₄ alkyl, SO₂ -di-C₁ -C₄ alkylamino or CO₂ --C₁ -C₄ alkyl;

Q is S or S(O)_(n) ; and

R₂ is H, halogen, CF₃, NO₂, C₁ -C₄ alkyl or C₁ -C₄ alkoxy.

This application generically discloses some of the compounds of theinstant invention.

U.S. Pat. No. 4,521,597 discloses a process for the preparation ofherbicidal sulfonamides of the formula ##STR24## wherein R₃ is H, F, Cl,Br, NO₂, OCH₃ or CF₃ ;

R₅ is S(O)_(m) C₁ -C₅ alkyl, SO₂ NR₈ R₉ or COR₇ ; and

R₆ is H, F, CH₃ or OCH₃.

This patent generically discloses some, but does not claim any,compounds of the instant invention.

EP-A-184,385, published Jun. 11, 1986, discloses the following compoundfor selective weed control in tomatoes and turf. ##STR25##

U.S. Ser. No. 874,307 discloses herbicidalo-alkylcarbonyl-pyridinesulfonylureas.

U.S. Ser. No. 943,137 discloses herbicidalo-substituted-pyridinesulfonylureas.

SUMMARY OF THE INVENTION

This application pertains to novel compounds of Formula I,agriculturally suitable compositions containing them and theirmethod-of-use as preemergent and/or postemergent herbicides or plantgrowth regulants. ##STR26## where J is ##STR27## R is H or CH₃ ; W is Oor S;

R₁ is R_(f) or R_(g) ;

R_(f) is H, C₁ -C₃ alkyl, C₁ -C₃ haloalkyl, halogen, NO₂, C₁ -C₃ alkoxy,C₁ -C₃ alkylthio or CN;

R_(g) is C₁ -C₃ haloalkyl, C₂ -C₃ alkyl, cyclopropyl, C₁ -C₃ alkylsubstituted by C₁ -C₃ alkoxy, OH, C₁ -C₂ alkylthio or CN, CN, W₂ R₁₁,amino, C₁ -C₃ alkylamino or C₁ -C₃ dialkylamino;

R₂ is C₁ -C₄ alkylsulfinyl, C₁ -C₄ alkylsulfonyl, C₃ -C₅ cycloalkylthio,C₃ -C₅ cycloalkylsulfinyl, C₃ -C₅ cycloalkylsulfonyl, SO₂ NH₂, SO₂NR_(d) R_(e), SO₂ NR'₇ R₈, SO₂ NR₇ R₈, OSO₂ R₈, SO₂ OR₈, N₃, P(W₁)(OC₁-C₂ alkyl)₂, CN, CO₂ R₉, CO₂ R'₉, CH₂ F, CF₂ H, CH₂ Cl, CCl₂ H or C₂ -C₄haloalkyl;

R₃ is C₁ -C₄ alkylsulfinyl, C₃ -C₅ cycloalkylthio, C₃ -C₅cycloalkylsulfinyl, C₃ -C₄ cycloalkylsulfonyl, SO₂ NH₂, SO₂ NR_(d)R_(e), SO₂ NR₇ R₈, SO₂ NR'₇ R₈, OSO₂ R₈, SO₂ OR₈, N₃, P(W₁)(OC₁ -C₂alkyl)₂, CN, CO₂ R₉, CO₂ R'₉ or C₁ -C₄ haloalkyl;

R₄ is C₁ -C₄ alkylsulfinyl, C₃ -C₅ cycloalkylthio, C₃ -C₅cycloalkylsulfinyl, C₃ -C₄ cycloalkylsulfonyl, SO₂ NH₂, SO₂ NR_(d)R_(e), SO₂ NR₇ R₈, OSO₂ R₈, SO₂ OR₈, N₃, P(W₁)(OC₁ -C₂ alkyl)₂, CN, CO₂R₉ or C₁ -C₄ haloalkyl;

R₅ is C₁ -C₄ alkylsulfinyl, C₁ -C₄ alkylsulfonyl, C₃ -C₅ cycloalkylthio,C₃ -C₅ cycloalkylsulfinyl, C₃ -C₅ cycloalkylsulfonyl, SO₂ NH₂, SO₂NR_(d) R_(e), SO₂ NR₇ R₈, OSO₂ R₈, SO₂ OR₈, N₃, P(W₁)(OC₁ -C₂ alkyl)₂,CN, CO₂ R₉ or C₁ -C₄ haloalkyl;

R₆ is C₁ -C₄ alkylthio, C₁ -C₄ alkylsulfinyl, C₁ -C₄ haloalkylthio, C₁-C₄ haloalkylsulfinyl, C₁ -C₄ haloalkylsulfonyl, C₃ -C₄ alkenylthio, C₃-C₄ alkenylsulfinyl, C₃ -C₄ alkenylsulfonyl, C₃ -C₄ alkynylthio, C₃ -C₄alkynylsulfinyl, C₃ -C₄ alkynylsulfonyl, C₃ -C₅ cycloalkylthio, C₃ -C₅cycloalkylsulfinyl, C₃ -C₅ cycloalkylsulfonyl, SO₂ NR_(d) R_(e), SO₂ NR₇R₈, OSO₂ R₈, SO₂ OR₈, N₃, P(W₁)(OC₁ -C₂ alkyl)₂, CN, CO₂ R₉ or C₁ -C₄haloalkyl;

R₇ is H, C₂ -C₃ cyanoalkyl, C₃ -C₄ alkenyl or C₃ -C₄ alkynyl;

R'₇ is C₁ -C₄ alkyl;

R₈ is C₁ -C₄ alkyl, C₁ -C₄ haloalkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₂-C₄ alkoxyalkyl or cyclopropyl; or

R₇ and R₈ may be taken together as --(CH₂)₃ --, --(CH₂)₄ --, --(CH₂)₅ --or --CH₂ CH₂ OCH₂ CH₂ --;

R₉ is CH₂ CH₂ R₁₀, CH₂ CF₃, C₃ -C₄ haloalkyl, C₃ -C₄ alkynyl, C₂ -C₄alkylthioalkyl, C₃ -C₅ cycloalkyl or C₄ -C₇ cycloalkylalkyl;

R'₉ is C₁ -C₄ alkyl, C₃ -C₄ alkenyl, CH₂ CH₂ Cl, CH₂ CH₂ Br, CH₂ CH₂OCH₃ or CH₂ CH₂ OC₂ H₅ ;

R₁₀ is OH, F, CN, OSO₂ (C₁ -C₃ alkyl) or OSO₂ (C₁ -C₃ haloalkyl);

R₁₁ is C₁ -C₃ alkyl, C₁ -C₃ haloalkyl, C₃ -C₄ alkenyl or C₃ -C₄ alkynyl;

W₁ is O or S;

W₂ is O or S;

A is ##STR28## X is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₂ -C₄ haloalkyl, C₁-C₄ haloalkyl, C₂ -C₄ haloalkylthio, C₁ -C₄ alkylthio, halogen, C₂ -C₅alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino or di(C₁ -C₃alkyl)amino;

Y is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₂ -C₄ haloalkoxy, C₂ -C₄haloalkylthio, C₁ -C₄ alkylthio, C₂ -C₅ alkoxyalkyl, C₂ -C₅alkoxyalkoxy, amino, C₁ -C₃ alkylamino, di(C₁ -C₃ alkyl)amino, C₃ -C₄alkenyloxy, C₃ -C₄ alkynyloxy, C₂ -C₅ alkylthioalkyl, C₂ -C₅alkylsulfinylalkyl, C₂ -C₅ alkylsulfonylalkyl, C₁ -C₄ haloalkyl, C₂ -C₄alkynyl, C₃ -C₅ cycloalkyl, azido, ##STR29## or N(OCH₃)CH₃ ;

m is 2 or 3;

Q₁ and Q₂ are independently O or S;

R_(a) is H or C₁ -C₃ alkyl;

R_(b) and R_(c) are independently C₁ -C₃ alkyl;

R_(d) is H or C₁ -C₂ alkyl;

R_(e) is C₁ -C₂ alkoxy;

Z is CH, N, CCH₃, CC₂ H₅, CCl or CBr;

Y₁ is O or CH₂ ;

X₁ is CH₃, OCH₃, OC₂ H₅ or OCF₂ H;

X₂ is CH₃, C₂ H₅ or CH₂ CF₃ ;

Y₂ is OCH₃, OC₂ H₅, SCH₃, SC₂ H₅, CH₃ or CH₂ CH₃ ;

X₃ is CH₃ or OCH₃ ;

Y₃ is H or CH₃ ;

X₄ is CH₃, OCH₃, OC₂ H₅, CH₂ OCH₃ or Cl;

Y₄ is CH₃, OCH₃, OC₂ H₅ or Cl;

and their agriculturally suitable salts; provided that

1) when X is halogen, then Z is CH and Y is OCH₃, OC₂ H₅, NH₂, NHCH₃,N(CH₃)₂ or N(OCH₃)CH₃ ;

2) when W is S, then R is H, A is A-1, Z is CH or N, and Y is CH₃, OCH₃,OC₂ H₅, CH₂ OCH₃, C₂ H₅, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C═CH, OCH₂ CH₂OCH₃, CH(OCH₃)₂ or ##STR30## 3) when the total number of carbon atoms ofX and Y is greater than four, then the combined number of carbons of R₁,R₂, R₃, R₄, R₅ or R₆ is less than or equal to six;

4) when J is J-1 and R₂ is C₁ -C₄ alkylsulfinyl, C₁ -C₄ alkylsulfonyl,SO₂ NR_(d) R_(e), SO₂ NR'₇ R₈ or CO₂ R'₉, or when J is J-2 and R₃ is C₁-C₄ alkylsulfinyl, CF₃, SO₂ NR_(d) R_(e), SO₂ NR'₇ R₈ or CO₂ R'₉, then Yis other than C₂ -C₅ alkylthioalkyl, C₂ -C₅ alkylsulfinylalkyl, C₂ -C₅alkylsulfonylalkyl, ##STR31## 5) when J is J-2 or J-3 and R₃ or R₄ is C₁-C₄ alkylsulfinyl, then X and Y are other than NH₂ or NHCH₃ ;

6) when J is J-2 and R₃ is C₁ -C₄ alkylsulfinyl or SO₂ NR_(d) R_(e), orR₇ is H, then X and Y are other than C₂ -C₄ haloalkoxy;

7) when J is J-5, then R₇ is other than H and R₆ is other than SO₂NR_(d) R_(e) ;

8) when J is J-2 and R₃ is SO₂ NH₂ or SO₂ NR_(d) R_(e), or R₇ is H, thenX is other than iodine;

9) when J is J-2 and R₇ is H or R₃ is SO₂ NR_(d) R_(e), then Y is otherthan C₂ -C₄ alkynyl;

10) X₄ and Y₄ are not simultaneously Cl;

11) when J is J-1, J-2, J-3, J-4 and A is A-5, then R_(f) is other thanH;

12) when J is J-1 or J-2, then A is other than A-6;

13) when J is J-1 and A is A-7, then R₂ is other than C₁ -C₄alkylsulfonyl;

14) when R₂ or R₃ is CO₂ R'₉ or SO₂ NR'₇ R₈ then R₁ is R_(g) and when R₂or R₃ is other than CO₂ R'₉ or SO₂ NR'₇ R₈, then R₁ is R_(f) ; and

15) when J is J-2 and R₁ i s adjacent to the sulfonylurea bridge, thenR_(g) is C₁ -C₃ haloalkyl, C₂ -C₃ alkyl, cyclopropyl, CN, W₂ R₁₁, amino,C₁ -C₃ alkylamino or C₁ -C₃ dialkylamino.

In the above definitions, the term "alkyl", used either alone or incompound words such as "alkylthio" or "haloalkyl", denotes straightchain or branched alkyl, e.g. methyl, ethyl, n-propyl, isopropyl or thedifferent butyl isomers.

Alkoxy denotes methoxy, ethoxy, n-propyloxy or isopropyloxy.

Alkenyl denotes straight chain or branched alkenes, e.g. 1-propenyl,2-propenyl, 3-propenyl and the different butenyl isomers.

Alkynyl denotes straight chain or branched alkynes, e.g. ethynyl,1-propynyl, 2-propynyl and the different butynyl isomers.

Alkylsulfonyl denotes methylsulfonyl, ethylsulfonyl and the differentpropylsulfonyl and butylsulfonyl isomers.

Cycloalkyl denotes cyclopropyl, cyclobutyl and cyclopentyl.

The term "halogen", either alone or in compound words such as"haloalkyl", denotes fluorine, chlorine, bromine or iodine. Further,when used in compound words such as "haloalkyl" said alkyl may bepartially halogenated or fully substituted with halogen atoms which maybe the same or different. Examples of haloalkyl include CH₂ CH₂ F, CF₂CF₃ and CH₂ CHFCl. Similarly, this definition applies to haloalkoxy andhaloalkylthio.

The total number of carbon atoms in a substituent group is indicated bythe C_(i) -C_(j) prefix where i and j are numbers from 1 to 5. Forexample, C₁ -C₃ alkylsulfonyl would designate methylsulfonyl throughpropylsulfonyl, C₂ alkoxyalkoxy would designate OCH₂ OCH₃, C₂ cyanoalkylwould designate CH₂ CN and C₃ cyanoalkyl would designate CH₂ CH₂ CN andCH(CN)CH₃.

Preferred Compounds

Preferred for reasons of increased ease of synthesis and/or greaterherbicidal efficacy are:

1. Compounds of Formula I where

X is C₁ -C₂ alkyl, C₁ -C₂ alkoxy, Cl, F, Br, I, CH₂ F, CF₃, OCH₂ CH₂ F,OCH₂ CHF₂, OCH₂ CF₃, CH₂ Cl or CH₂ Br; and

Y is H, C₁ -C₂ alkyl, C₁ -C₂ alkoxy, CH₂ OCH₃, CH₂ OCH₂ CH₃, NHCH₃,N(OCH₃)CH₃, N(CH₃)₂, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, OCH₂ CH₂OCH₃, ##STR32## CH₂ SCH₃, cyclopropyl, C.tbd.CH or C.tbd.CCH₃ ; R_(a) isH or CH₃ ; and

Z is CH or N.

2. Compounds of Preferred 1 where

W is O;

R_(f) is H, CH₃, Cl haloalkyl, halogen or OCH₃ ;

R_(g) is C₁ -C₂ haloalkyl, ethyl, W₂ R₁₁, CH₂ OCH₃, CH₂ SCH₃, CH₂ CN, C₁-C₂ alkylamino or N(CH₃)₂ ;

R₂ is C₁ -C₄ alkylsulfinyl, C₁ -C₄ alkylsulfonyl, SO₂ NH₂, SO₂ NR_(d)R_(e), SO₂ NR₇ R₈, SO₂ NR'₇ R₈ OSO₂ R₈, SO₂ OR₈, N₃, P(W₁)(OC₁ -C₂alkyl)₂, CN, CO₂ R₉, CO₂ R'₉, CHF₂, CF₂ H, CH₂ Cl, CCl₂ H or C₂ -C₄haloalkyl;

R₃ is C₁ -C₄ alkylsulfinyl, SO₂ NH₂, SO₂ NR_(d) R_(e), SO₂ R₇ R₈, SO₂NR'₇ R₈, OSO₂ R₈, SO₂ OR₈, N₃, P(W₁)(OC₁ -C₂ alkyl)₂, CN, CO₂ R₉, CO₂R'₉ or C₁ -C₄ haloalkyl;

R₄ is C₁ -C₄ alkylsulfinyl, SO₂ NH₂, SO₂ N(OCH₃)CH₃, SO₂ NR₇ R₈, OSO₂R₈, SO₂ OR₈, N₃, P(W₁)(OC₁ -C₂ alkyl)₂, CN, CO₂ R₉ or C₁ -C₄ haloalkyl;

R₅ is C₁ -C₄ alkylsulfinyl, C₁ -C₄ alkylsulfonyl, SO₂ NH₂, SO₂N(OCH₃)CH₃, SO₂ NR₇ R₈, OSO₂ R₈, SO₂ OR₈, N₃, P(W₁)(OC₁ -C₂ alkyl)₂, CN,CO₂ R₉ or C₁ -C₄ haloalkyl;

R₆ is C₁ -C₄ alkylthio, C₁ -C₄ alkylsulfinyl, C₁ -C₄ haloalkylthio, C₁-C₄ haloalkylsulfinyl, C₁ -C₄ haloalkylsulfonyl, C₃ -C₄ alkenylthio, C₃-C₄ alkenylsulfinyl, C₃ -C₄ alkenylsulfonyl, C₃ -C₄ alkynylthio, C₃ -C₄alkynylsulfinyl, C₃ -C₄ alkynylsulfonyl, SO₂ N(OCH₃)CH₃, SO₂ NR₇ R₈,OSO₂ R₈, SO₂ OR₈, N₃, P(W₁)(OC₁ -C₂ alkyl)₂, CN, CO₂ R₉ or C₁ -C₄haloalkyl;

R₇ is H, C₂ -C₃ cyanoalkyl, C₃ -C₄ alkenyl or C₃ -C₄ alkynyl;

R₈ is C₁ -C₄ alkyl, C₁ -C₄ haloalkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₂-C₄ alkoxyalkyl or cyclopropyl; and

R₁₁ is C₁ -C₃ alkyl, C₁ -C₂ haloalkyl, allyl or propargyl.

3. Compounds of Preferred 2 where J is J-1.

4. Compounds of Preferred 2 where J is J-2.

5. Compounds of Preferred 2 where J is J-3.

6. Compounds of Preferred 2 where J is J-4.

7. Compounds of Preferred 2 where J is J-5.

8. Compounds of Preferred 3 where

R₇ is H, C₂ -C₃ cyanoalkyl, allyl or propargyl;

R'₇ is C₁ -C₃ alkyl;

R₈ is C₁ -C₃ alkyl, allyl, propargyl or cyclopropyl;

R₉ is CH₂ CH₂ R₁₀, CH₂ CH₂ SCH₃, Propargyl or cyclopropylmethyl;

R'₉ is C₁ -C₃ alkyl, allyl, CH₂ CH₂ OCH₃ or CH₂ CH₂ Cl; and

R₁₀ is OH, CN or OSO₂ CH₃.

9. Compounds of Preferred 8 where

A is A-1;

X is CH₃, OCH₃, OCH₂ CH₃, Cl or OCH₂ CF₃ ; and

Y is CH₃, OCH₃, CH₂ CH₃, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.

10. Compounds of Preferred 9 where Z is CH.

11. Compounds of Preferred 9 where Z is N.

12. Compounds of Preferred 4 where

R₇ is H, C₂ -C₃ cyanoalkyl, allyl or propargyl; and

R₈ is C₁ -C₃ alkyl, allyl, propargyl or cyclopropyl.

13. Compounds of Preferred 12 where

A is A-1;

X is CH₃, OCH₃, OCH₂ CH₃, Cl or OCH₂ CF₃ ; and

Y is CH₃, OCH₃, CH₂ CH₃, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.

14. Compounds of Preferred 13 where Z is CH.

15. Compounds of Preferred 13 where Z is N.

16. Compounds of Preferred 5 where

R₇ is H, C₂ -C₃ cyanoalkyl, allyl or propargyl; and

R₈ is C₁ -C₃ alkyl, allyl, propargyl or cyclopropyl.

17. Compounds of Preferred 16 where

A is A-1;

X is CH₃, OCH₃, OCH₂ CH₃, Cl or OCH₂ CF₃ ; and

Y is CH₃, OCH₃, CH₂ CH₃, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.

18. Compounds of Preferred 17 where Z is CH.

19. Compounds of Preferred 17 where Z is N.

20. Compounds of Preferred 6 where

R₇ is H, C₂ -C₃ cyanoalkyl, allyl or propargyl; and

R₈ is C₁ -C₃ alkyl, allyl, propargyl or cyclopropyl.

21. Compounds of Preferred 20 where

A is A-1;

X is CH₃, OCH₃, OCH₂ CH₃, Cl or OCH₂ CF₃ ; and

Y is CH₃, OCH₃, CH₂ CH₃, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.

22. Compounds of Preferred 21 where Z is CH.

23. Compounds of Preferred 22 where Z is N.

24. Compounds of Preferred 7 where

R₆ is C₁ -C₂ alkylthio, C₁ -C₂ alkylsulfinyl,

C₁ -C₂ haloalkylthio, C₁ -C₂ haloalkylsulfinyl, C₁ -C₂haloalkylsulfonyl, SO₂ N(OCH₃)CH₃ or SO₂ NR₇ R₈ ;

R₇ is H, C₂ -C₃ cyanoalkyl, allyl or propargyl;

R₈ is C₁ -C₃ alkyl, allyl, propargyl or cyclopropyl.

25. Compounds of Preferred 24 where

A is A-1;

X is CH₃, OCH₃, OCH₂ CH₃, Cl or OCH₂ CF₃ ; and

Y is CH₃, OCH₃, CH₂ CH₃, CH₂ OCH₃, NHCH₃ or CH(OCH₃)₂.

26. Compounds of Preferred 25 where Z is CH.

27. Compounds of Preferred 25 where Z is N.

28. Compounds of Preferred 1 where

J is J-1;

A is A-1;

Z is CH;

W is O;

R₂ is C₁ -C₄ alkylsulfinyl or C₁ -C₄ alkylsulfonyl; and

R_(f) is H, C₁ -C₂ alkyl, C₁ haloalkyl, C₁ -C₂ alkoxy or C₁ -C₂thioalkyl.

29. Compounds of Preferred 28 where

R_(f) is H;

R₂ C₁ -C₄ alkylsulfonyl;

X is OCH₃ ; and

Y is OCH₃.

Specifically Preferred for reasons of greatest ease of synthesis and/orgreatest herbicidal efficacy are:

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3-(1-propylsulfonyl)-2-pyridinesulfonamide;

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3-(1-propylsulfinyl)-2-pyridinesulfonamide;

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3-(ethylsulfonyl)-2-pyridinesulfonamide;

N2-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-N3-ethyl-2,3-pyridinedisulfonamide;

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3-(methylsulfonyloxy)-2-pyridinesulfonamide;and

N2-[(4,6-dimethoxypyrimidin-2-yl)-aminocarbonyl]-N3-methyl-2,3-pyridinedisulfonamide.

This invention also pertains to novel compounds of the followingformulas ##STR33## wherein X_(a) is Cl, NH₂, HNC(CH₃)3 and ##STR34##which are useful as intermediates to herbicidal sulfonylureas.

Specifically preferred are:

3-ethylsulfonyl-2-pyridinesulfonamide and

N3-methyl-2,3-pyridinedisulfonamide.

DETAILED DESCRIPTION OF THE INVENTION Synthesis

Compounds of Formula I can be synthesized either by one or more of themethods described in U.S. Pat. No. 4,456,469, or by the reaction ofsulfonamides II with the phenyl ester of the appropriate carbamic acidIII in the presence of an equimolar quantity of a tertiary amine basesuch as 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) as shown in Equation 1.##STR35## wherein J, R, and A are as previously defined.

The reaction shown in Equation 1 is best carried out at 25° C. in asolvent such as dioxane or acetonitrile for 1-2 hours under an inertatmosphere as described in European Patent Application No. 70,804(Published Jan. 26, 1983). The desired products of Formula I can beconveniently isolated by acidifying the reaction solution with aqueoushydrochloric acid. Alternatively, the aqueous layer can be extractedwith a solvent such as methylene chloride or ethyl acetate. Drying andevaporation of the solvent affords the desired products. The phenylcarbamates can be synthesized by treatment of the correspondingheterocyclic amines of Formula A-NHR with diphenyl carbonate or phenylchloroformate in the presence of a base such as sodium hydride,pyridine, or potassium carbonate with a catalytic amount of4-dimethylaminopyridine. The mixture is stirred at temperatures between25° and 65° C. in a suitable solvent such as tetrahydrofuran for 12-36hours.

The required sulfonamides of Formula II can be synthesized by either oneof the methods shown below in Equations 2 and 3.

Equation 2 depicts the reaction of sulfonyl chlorides of Formula IV withammonia to give sulfonamides of Formula II. ##STR36## wherein

J is as previously defined.

The amination of Equation 2 is conveniently effected by adding at leasttwo molar equivalents of either anhydrous ammonia or concentratedammonium hydroxide to a solution of the sulfonyl chloride IV in asuitable solvent such as diethyl ether, tetrahydrofuran or methylenechloride at temperatures between -30° and 25° C. The desiredsulfonamides of Formula II are isolated either by filtration, in whichcase the by-product ammonium chloride is removed by washing with water,or extraction into a suitable organic solvent such as methylene chlorideor ethyl acetate. Drying and evaporation of the solvent then affords theproducts II which are usually sufficiently pure to be carried directlyon to the next step.

Sulfonamides of Formula II can also be prepared as shown in Equation 3by treatment of the corresponding N-t-butylsulfonamides VI with anappropriate acid such as trifluoroacetic (TFA), polyphosphoric (PPA), orp-toluenesulfonic acid (p-TSA). ##STR37## wherein J is as previouslydefined.

The reaction of Equation 3 is conveniently carried out by stirring asolution of the compound of Formula VI in excess trifluoroacetic acid(approximately 0.3M) at about 25° C. for 1-72 hours. The desiredsulfonamides of Formula II are then isolated by removal of the volatilesin vacuo and crystallization from a suitable solvent such as diethylether, 1-chlorobutane, or ethyl acetate. Alternatively, theN-t-butylsulfonamides of Formula VI can be treated with a catalyticamount of p-toluenesulfonic acid monohydrate in a solvent such astoluene or xylenes at reflux temperature for 1-6 hours. The desiredproducts are then isolated in a manner analogous to the one describedabove. For use of polyphosphoric acid in the deprotection ofN-t-butylsulfonamides, see J. G. Lombardino, J. Org. Chem. 36, 1843(1971); for use of trifluoroacetic acid, see J. D. Catt and W. L.Matier, J. Org. Chem. 38, 1974 (1973).

Sulfonamides of Formula VI can be prepared by the reaction of sulfonylchlorides of Formula IV with excess t-butyl amine as shown in Equation4. ##STR38## wherein J is as previously defined.

Sulfonyl chlorides of Formula IV can be prepared according to theprocedures described in U.S. Pat. No. 4,456,469. Alternatively, theprocedures of South African Patent Application 84/8844 may be utilizedwhich describe the conversion of mercapto or arylmethylthio compounds tosulfonyl chlorides via treatment with hypochlorite solution.

Sulfonyl chlorides of Formula IVa may also be prepared via metallationof 2-fluoropyridine derivatives with lithium diisopropyl amide (LDA)according to the procedure of T. Gungor, F. Marsais and G. Queguiner, J.Organomet. Chem. 1981, 215, 139-150, followed by treatment with sulfurdioxide and N-chlorosuccinimide (NCS) as shown in Equation 5. ##STR39##wherein R₁ is as previously defined.

Sulfonyl chlorides of Formula IVb can be Prepared from compounds ofFormula VII as shown in Equation 6 and described in U.S. Pat. No.4,420,325. ##STR40## wherein J is as previously defined; and

[X] is a suitable halogenating reagent which would be obvious to oneskilled in the art.

The sulfides of Formula VIII can be prepared by the reaction of a halopyridine compound of Formula IX with an appropriate mercaptan in thepresence of a base as described in U.S. Pat. No. 4,456,469 and shown inEquation 7. ##STR41## wherein X' is F, Cl, or Br; and

R' is C₁ -C₄ alkyl or benzyl.

The sulfides of Formula VIIIa can be prepared by metallation of thepyridine compound of Formula X with two equivalents of a strong basesuch as n-butyllithium or lithium diisopropylamide (LDA) as described byP. Breant, F. Marsais, and G. Queguiner, Synthesis, 1983, 822-824,followed by treatment with the appropriate disulfide as shown inEquation 8. ##STR42## R' is C₁ -C₄ alkyl, C₃ -C₅ cycloalkyl or benzyl;and

R₁ is as previously defined.

In an analogous manner, sulfides of Formula VIIIb can be prepared asshown in Equation 9. ##STR43## wherein R' is C₁ -C₄ alkyl, C₃ -C₅cycloalkyl, or benzyl; and

R₁ is as previously defined.

Sulfides of Formula VIIIc can be prepared by the metallation of a2-fluoropyridine derivative as described previously and again followedby treatment with an appropriate disulfide as shown in Equation 10.##STR44## wherein R' is C₁ -C₄ alkyl, C₃ -C₅ cycloalkyl, or benzyl; and

R₁ is as previously defined.

The sulfones and sulfoxides of General Formula XI can be prepared fromthe corresponding sulfides of Formula VIIId by any one of the numerousoxidation reagents [O] known in the art such as hydrogen peroxide orperacids, as shown in Equation 11. ##STR45## wherein R' is C₁ -C₄ alkylor C₃ -C₅ cycloalkyl; and

n is 1 or 2.

The chloropyridine of Formula IXa can be prepared by diazotization of3-amino-2-chloropyridine followed by displacement with cuprous cyanideas shown in Equation 12. The diazonium group can also be replaced byother groups such as SO₂ Cl and N₃ by those skilled in the art viamethods known in the literature. ##STR46## wherein R₁ is as previouslydefined.

The sulfides of General Formula VIIIf can be prepared as shown inEquation 13. Alkylation of a 3-hydroxy-2-mercaptopyridine derivativewith alkyl halides utilizing a variety of bases such as potassiumcarbonate or potassium t-butoxide afforded the sulfides of Formula VIIIewhich were then treated with the appropriate sulfonyl chlorides in thepresence of an acid acceptor such as triethylamine to afford sulfides ofFormula VIIIf. ##STR47## wherein R' is C₁ -C₄ alkyl or benzyl;

X' is Cl, Br, or I; and

R₁ and R₈ are as previously defined.

The esters of Formula VIIIg, VIIIh, and VIIIj can be prepared by eitherof the two methods shown in Equation 14. The first method involvesmetallation of a 2-fluoropyridine derivative as previously described inEquation 5, followed by treatment with ethyl or methyl chloroformatewhich afforded esters of Formula XIII. Mercaptide displacement asdescribed in Equation 7 resulted in esters of Formula VIIIg. Acidcatalyzed transesterification using the appropriate alcohol as thesolvent afforded esters of Formula VIIIh.

The second method involves the alkylation of a 2-mercaptonicotinic acidderivative VIIIi with alkyl halides utilizing a variety of bases such aspotassium carbonate or potassium t-butoxide, followed by conversion tothe acid halides by any number of standard reagents such as thionylchloride, phosphorous trichloride or pentachloride, or oxalyl chloride.The acid chlorides were then treated with the appropriate alcohols inthe presence of an acid acceptor such as triethylamine, to afford estersof Formula VIIIh. Conversion of the sulfides VIIIh to the sulfonamidesVIIIj was carried out as previously described. ##STR48## wherein R₉ canalso be R'₉ ; and

X', R', R₁, R₉ and R'₉ are as previously defined.

The sulfonamides of General Formula XIIa can be prepared as shown inEquation 15. However, for the preparation of primary or unhinderedsecondary sulfonamides, a protective group is needed for a later stagein the synthetic sequence. A representative example is shown in Equation16 where a t-butyl protective group is utilized for the synthesis ofsulfonamide IIa. ##STR49## wherein [D] is R_(d) R_(e), R₇ R₈, R'₇ R₈, orH₂ ; and R₁, R_(d), R_(e), R₇, R₈ and R'₇ are as previously defined.##STR50## wherein R₁ is as previously defined.

The difluoro compounds of Formula XIVa in Equation 17 can be preparedusing the reactions previously described. Treatment with one equivalentof various R₁ nucleophiles (those that are available in the art) resultsin a mixture of products which can be separated. An example of the useof sodium methoxide as the reactive nucleophile is shown. IntermediatesXIVb and XIVc can be separated and further derivatized as previouslydescribed. ##STR51## wherein R₂ is as previously defined.

An alternative method to prepare esters of Formula XVd is shown inEquation 18. Mercaptide displacement of a 2,6-dihalopyridine can beachieved followed by conversion to the sulfonamide XVa as previouslydescribed. Treatment with two equivalents of a strong base such asn-butyllithium in a similar manner to that described by P. Breant, F.Marsalis, and G. Queguiner, Synthesis, 1983, 822-824, followed bytreatment with carbon dioxide affords the acids of Formula XVb. Theacids can then be treated with various R₁ nucleophiles such asalkoxides, mercaptides or amines to afford the acids of Formula XVc(using sodium methoxide as an example) which can then be esterified withthe appropriate alcohols utilizing standard 1,3-dicyclohexylcarbodiimide(DCC) coupling conditions to afford esters of Formula XVd. ##STR52##wherein R₉ can also be R'₉ ;

X' is F or Cl; and

R', R₉ and R'₉ are as previously defined.

In an analogous manner, sulfonamides of General Formula XVIb can beprepared as shown in Equation 19. Treatment of XVa with strong basefollowed by an appropriate disulfide affords sulfides of Formula XVIa.Further elaboration utilizing chemistry previously described affordssulfonamides of Formula XVIb. ##STR53## wherein X' is F or Cl; and

R' and [D] are as previously defined.

A choice by one skilled in the art of the appropriate methods forpreparing compounds of Formula I must take into account the nature ofthe substituents R₁ through R₁₁, and R_(d) through R_(g), and theirchemical compatibility with the reaction conditions of Equations 1through 19.

The heterocyclic amines of Formula A-NHR in Equation 1 above can beprepared by methods known in the literature, or simple modificationsthereof, by those skilled in the art. For instance, EP-A No. 84,224(published Jul. 27, 1983) and W. Braker et al., J. Chem. Soc., 69, 3072(1947) describes methods for preparing aminopyridines and triazinessubstituted by acetal groups such as dialkoxymethyl or1,3-dioxolan-2-yl, among other groups. Also, for example, South Africanpatent application Nos. 82/5045 and 82/5671 describe methods forpreparing aminopyrimidines and triazines substituted by haloalkyl orhaloalkylthio groups such as OCH₂ CH₂ F, OCH₂ CF₃, SCF₂ H, or OCF₂ H,among other groups. South African patent application No. 83/7434(published Oct. 5, 1983) describes methods for the synthesis ofcyclopropylpyrimidines and triazines substituted by such groups asalkyl, haloalkyl, alkoxy, haloalkoxy, alkylamino, dialkylamino oralkoxyalkyl.

The 5,6-dihydrofuro[2.3-d]pyrimidine-2-amines, thecyclopenta[d]pyrimidine-2-amines (A is A-2) and the6,7-dihydro-5H-pyrano[2.3-d]pyrimidin-2-amines (A is A-3) can beprepared as described in EP-A No. 15,683. Thefuro[2.3-d]pyrimidin-2-amines (A is A-4) are described in EP-A No.46,677.

Compounds of Formula A-NHR where A is A-5 are described in EP-A-73,562.Compounds where A is A-6 are described in EP-A-94,260.

In addition, general methods for preparing aminopyrimidines andtriazines have been reviewed in the following publications:

"The Chemistry of Heterocyclic Compounds", a series published byInterscience Publishers, Inc., New York and London;

"Pyrimidines", Vol. 16 of the same series by D. J. Brown;

"s-Triazines and Derivatives", Vol. 13 of the same series by E. M.Smolin and L. Rappoport; and

F. C. Schaefer, U.S. Pat. No. 3,154,547 and K. R. Huffman and F. C.Schaefer, J. Org. Chem., 28, 1812 (1963), which describes the synthesisof triazines.

Preparation in view of the above would be obvious to one skilled in theart. Agriculturally suitable salts of compounds of Formula I are alsouseful herbicides and can be prepared in a number of ways known to theart. For example, metal salts can be made by contacting compounds ofFormula I with a solution of an alkali or alkaline earth metal salthaving a sufficiently basic anion (e.g., hydroxide, alkoxide, carbonateor hydroxide). Quaternary amine salts can be made by similar techniques.

Salts of compounds of Formula I can also be prepared by exchange of onecation for another. Cationic exchange can be effected by direct contactof an aqueous solution of a salt of a compound of Formula I (e.g.,alkali or quaternary amine salt) with a solution containing the cationto be exchanged. This method is most effective when the desired saltcontaining the exchanged cation is insoluble in water and can beseparated by filtration.

Exchange may also be effected by passing an aqueous solution of a saltof a compound of Formula I (e.g., an alkali metal or quaternary aminesalt) through a column packed with a cation exchange resin containingthe cation to be exchanged for that of the original salt and the desiredproduct is eluted from the column. This method is particularly usefulwhen the desired salt is water-soluble, e.g., a potassium, sodium orcalcium salt.

Acid addition salts, useful in this invention, can be obtained byreacting a compound of Formula I with a suitable acid, e.g.,p-toluenesulfonic acid, trichloroacetic acid or the like.

The preparation of the compounds of this invention is furtherillustrated by the following specific examples. Temperatures arereported in degrees Celsius; abbreviations for nuclear magneticresonance (NMR) are: s=singlet, d=doublet, t=triplet, m=multiplet, andpeak positions are reported as parts per million downfield from internaltetramethylsilane. Infrared (IR) peak positions are given in reciprocalcentimeters (cm⁻¹)

EXAMPLE 1

Preparation of 2-Fluoro-3-(propylthio)pyridine

To a stirred solution of 59 ml (0.113 mol) of 1.9 molar lithiumdiisopropyl amide (in hexanes) in 150 mls dry tetrahydrofuran cooled to-70° under nitrogen was added dropwise a solution of 10.0 g of2-fluoropyridine (0.103 mol) in 30 mls dry tetrahydrofuran such that thetemperature was maintained below -65°. The solution was stirred at -70°for 4 hours and a solution 17 g of n-propyldisulfide (0.113 mol) in 45mls dry tetrahydrofuran was added dropwise while maintaining thetemperature below -65°. After stirring another hour at -70°, thesolution was poured into water and extracted with ether. The combinedorganic phases were washed with brine, dried over magnesium sulfate, andevaporated to afford 14.5 g (82%) of a red oil: NMR (CDCl₃, 200 MHz),1.0 (3H, m), 1.7 (2H, m), 2.9 (2H, m), 7.1 (1H, m), 7.7 (1H, m), 8.0(1H, m); IR (neat) 1585, 1560, 1410, 1245 cm⁻¹.

EXAMPLE 2 Preparation of 2-(Phenylmethylthio)-3-(propylthio)pyridine

To a stirred suspension of 0.62 g (0.013 mol) of 50% sodium hydride (inmineral oil), which had been washed with hexanes, in 20 mls drydimethylformamide cooled to -5° under nitrogen was added dropwise 1.6 g(0.013 mol) benzyl mercaptan such that the temperature was maintainedbelow 5°. The suspension was stirred at room temperature for 1 hour,cooled to 0°, and a solution of 2.0 g (0.012 mol) of the product fromExample 1 was added dropwise while maintaining the temperature between0° and 5°. After warming to room temperature, the solution was pouredinto water and extracted with ether. The combined organic layers werewashed with water and with brine, dried over magnesium sulfate, andevaporated to an oil which was purified by flash chromatography toafford 0.9 g (27%) oil: NMR (CDCl₃, 200 Mhz), 1.02 (3H, t, J=7 Hz), 1.6(2H, m), 2.9 (2H, t, J=7 Hz), 4.45 (2H, s), 6.9-7.6 (7H, m), 8.3 (1H,m); IR (neat) 1560, 1370 cm⁻¹.

EXAMPLE 3 Preparation ofN-(1,1-Dimethylethyl)-3-(propylsulfinyl)-2-pyridinesulfonamide

To a vigorously stirred mixture of 0.5 g (0.0018 mol) of the productfrom Example 2 in 9 mls methylene chloride and 4 mls water cooled to 0°was added 0.7 mls (0.008 mol) concentrated hydrochloric acid followed bythe dropwise addition of 8.9 mls (0.006 mol) of a 5% sodium hypochloritesolution such that the temperature was maintained between 0° and 5°.After the mixture was stirred for an additional 30 minutes at 0° thereaction was poured into water and extracted with methylene chloride.The combined organic layers were washed with brine, dried over magnesiumsulfate, and filtered. The filtrate was stirred and cooled to -70° undernitrogen and 0.53 g (0.0072 mol) of t-butyl amine was added dropwise andthe mixture was allowed to warm to room temperature. The reaction waspoured into water and extracted with methylene chloride. The organiclayers were combined and washed with brine, dried over magnesiumsulfate, and evaporated to a mixture which was purified by flashchromatography to afford 0.4 g (69%) white solid: m.p. 138°-140°; NMR(CDCl₃, 200 Mhz) 1.09 (3H, m), 1.7 (1H, m), 2.0 (1H, m), 2.8 (1H, m),3.3 (1H, m), 5.2 (NH), 7.7 (1H, m), 8.6 (1H, m), 8.8 (1H, m); IR (nujol)3400, 1375, 1325, 1160, 1065, 1015 cm⁻¹.

EXAMPLE 4 Preparation of 3-(Propylsulfonyl)-2-pyridinesulfonamide

To a stirred solution of 8.8 g (0.029 mol) of the product from Example 3in 400 mls methylene chloride cooled to -5°, under nitrogen, was added6.6 g (0.038 mol) of 3-chloroperbenzoic acid and stirred at roomtemperature for 20 hours. The reaction mixture was poured into water andextracted with methylene chloride. The organic layers were combined andwashed with saturated sodium bisulfite and brine, dried over magnesiumsulfate, and evaporated to a solid mixture which was washed with hexanesto afford a white solid. The solid was dissolved and stirred in 150 mlstrifluoroacetic acid for 72 hours. The solution was evaporated andtriturated with ether to afford 5.3 g (46%) white solid: m.p. 153°-157°;NMR (CDCl₃, 200 MHz) 1.06 (3H, t, J=7 Hz), 1.8 (2H, m), 3.7 (2H, m) 5.8(NH₂), 7.8 (1H, m), 8.6 (1H, m), 8.95 (1H, m); IR (nujol) 3390, 3180,1360, 1310, 1175, 1150 cm⁻¹.

EXAMPLE 5 Preparation ofN-[(4,6-Dimethoxypyrimidin-2-yl)aminocarbonyl]-3-(propylsulfonyl)-2-pyridinesulfonamide

To a stirred suspension of 0.4 g (0.0015 mol) of the product fromExample 4 and 0.63 g (0.0023 mol) of phenyl(4,6-dimethoxypyrimidin-2-yl)carbamate in 4 mls acetonitrile was added0.35 g (0.0023 mol) of 1,8-diazabicyclo[5.4.0]undec-7-ene and stirredfor 30 minutes. The solution was diluted with water and acidified with 1normal hydrochloric acid. The resulting precipitate was collected andwashed with water and ether to afford 0.45 g (67%) white solid: m.p.168°-170°; NMR (CDCl₃, 200 Mhz), 1.07 (3H, t, J=7 Hz), 1.85 (2H, m), 3.7(2H, m), 3.97 (6H, s), 5.8 (1H, s), 7.26 (NH), 7.8 (1H, m), 8.6 (1H, m),8.9 (1H, m), 12.9 (NH); IR (nujol) 3320, 1740, 1610, 1580, 1375, 1195,1170 cm⁻¹.

EXAMPLE 6 Preparation of 3-ethylthio-2-fluoropyridine

Using the procedure of Example 1, 40.0 g of 2-fluoropyridine (0.412 mol)was converted to 46.5 g (72%) of the title compound as an oil:NMR(CDCl₃, 200 MHz) 1.3 (3H, t, J=7 Hz), 2.95 (2H, q, J=7 Hz), 7.1 (1H,m), 7.7 (1H, m), 8.0 (1H, m); lR (neat) 1585, 1565, 1410, 1230 cm⁻¹.

EXAMPLE 7 Preparation of 3-ethylthio-2-(phenylmethylthio)pyridine

Using the procedure of Example 2, 25.0 g (0.160 mol) of the product fromExample 6 was converted to 44.8 g (100%) of the title compound as ayellow liquid: NMR (CDCl₃, 200 Mhz) 1.28 (3H, t, J=7 Hz), 2.9 (2H, q,J=7 Hz), 4.45 (2H, s), 7.0-7.6 (7H, m), 8.35 (1H, m); lR (neat) 1610,1405 cm⁻¹.

EXAMPLE 8 Preparation ofN-(1,1-Dimethylethyl)-3-ethylsulfinyl-2-pyridinesulfonamide

Using the procedure of Example 3, 35.0 g (0.134 mol) of the product fromExample 7 was converted to 21.2 g (56%) of the title compound: m.p.129°-131°; NMR (CDCl₃, 200 Mhz) 1.23 (9H, s), 1.28 (3H, t, J=7 Hz), 2.9(1H, m), 3.3 (1H, m), 5.2 (NH), 7.7 (1H, m), 8.55 (1H, m), 8.75 (1H, m);lR (nujol) 3100, 1320, 1155 cm⁻¹.

EXAMPLE 9 Preparation ofN-(1,1-Dimethylethyl)-3-ethylsulfonyl-2-pyridinesulfonamide

Using the first half of the procedure of Example 4 (i.e., the3-chloroperbenzoic acid reaction), 9.0 g (0.033 mol) of the product fromExample 9 was converted to 10.1 g (100%) of the title compound: m.p.58°-63°; NMR (CDCl₃, 200 Mhz) 1.2 (3H, t. J=7 Hz), 1.2 (9H, s), 3.7 (2H,q, J=7 Hz), 6.1 (NH), 7.7 (1H, m), 8.55 (1H, m), 8.95 (1H, m); lR(nujol) 3300, 1560, 1350, 1300, 1170, 1140 cm⁻¹.

Using the second half of the procedure of Example 4 (i.e., thetrifluoroacetic acid reaction), 9.0 g (0.029 mol) of the product fromExample 9 was converted to 4.2 g (58%) of the title compound: m.p.211°-212.5°; NMR (DMSO-d₆, 200 Mhz) 1.15 (3H, t, J =7 Hz), 3.4 (NH₂),3.7 (2H, q, J=7 Hz), 7.9 (1H, m), 8.5 (1H, m), 8.95 (1H, m); IR (nujol)3370, 3190, 1350, 1310, 1180 cm⁻¹.

EXAMPLE 11 Preparation ofN-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3-ethylsulfonyl-2-pyridinesulfonamide

Using the procedure of Example 5, 0.60 g (0.0024 mol) of the productfrom Example 10 was converted to 0.70 g (70%) of the title compound:m.p. 160°-162°; NMR (CDCl₃, 200 Mhz) 1.35 (3H, t, J=7 Hz), 3.7 (2H, q,J=7 Hz), 3.97 (6H, s), 5.8 (1H, s), 7.3 (NH), 7.75 (1H, m), 8.6 (1H, m),8.9 (1H, m), 12.95 (NH); IR (nujol) 3260, 1740, 1610, 1360, 1195, 1175cm⁻¹.

EXAMPLE 12 Preparation of 2,6-Difluoro-3-pyridinecarboxylic acid, methylester

To a stirred solution of 91 ml (0.182 mol) of 2.0 molar lithiumdiisopropylamide (in hexanes) in 200 mL dry tetrahydrofuran cooled to-70° under nitrogen was added dropwise a solution of 20.0 g of2,6-difluoropyridine (0.174 mol) in 75 mL dry tetrahydrofuran such thatthe temperature was maintained below -60°. The solution was stirred at-70° for 3 hours and was then added via a cannula to a solution 21.7 g(0.230 mol) of methyl chloroformate in 100 mL dry tetrahydrofuran cooledto -70° under nitrogen. After stirring another hour at -70°, the mixturewas poured into water and extracted with ether. The combined organiclayers were washed with brine, dried over magnesium sulfate, andevaporated to a semisolid which was purified by flash chromatography toafford 13.0 g (43%) orange oil: NMR (CDCl₃, 200 Mhz) 3.95 (3H, s), 6.9(1H, m), 8.5 (1H, m); IR (neat) 1745, 1730, 1610, 1415, 1290 cm⁻¹.

EXAMPLE 13 Preparation of 2-Fluoro-6-Methoxy-3-Pyridinecarboxylic Acid,Methyl Ester

To a stirred solution of 15.0 g (0.0867 mol) of the product from Example12 in 240 mL dry tetrahydrofuran cooled to -78° was added dropwise 22.7mL (0.0993 mol) of 25% sodium methoxide in methanol solution over 45minutes. After warming to -20°, the mixture was poured into ice water,acidified with 1 normal hydrochloric acid and extracted with ether. Thecombined organic layers were washed with brine, dried over magnesiumsulfate, and evaporated to a semisolid which was purified by flashchromatography to afford 3.2 g (17%) light yellow solid: m.p. 81°-82°;NMR (CDCl₃, 200 Mhz) 3.9 (3H, s), 3.95 (3H, s), 6.67 (1H, d, J=9 Hz),8.25 (1H, m) IR (nujol) 1715, 1615, 1290 cm⁻¹.

EXAMPLE 14 Preparation of6-Methoxy-2-(Phenylmethylthio)-3-Pyridinecarboxylic Acid, Methyl Ester

To a stirred mixture of 0.8 g (0.0161 mol) of 50% sodium hydride (inmineral oil), which had been washed with hexanes, in 20 mL drydimethylformamide cooled to -5° under nitrogen was added dropwise 1.9 mL(0.0161 mol) benzyl mercaptan. The suspension was stirred at roomtemperature for 1 hour, cooled to 0°, and a solution of 3.2 g (0.0147mol) of the product of Example 13 in 20 mL dry dimethylformamide wasadded dropwise. After warming to room temperature, the solution waspoured into water and extracted with ether. The combined organic layerswere washed with water and with brine, dried over magnesium sulfate, andevaporated to an oil which was purified by flash chromatography toafford 3.0 g (64%) of a yellow solid: m.p. 67°-71°; NMR (CDCl₃, 200 Mhz)3.88 (3H, s), 3.96 (3H, s), 4.46 (2H, s), 6.44 (1H, d, J=9Hz), 7.2°-7.5(5H, m), 8.1 (1H, d, J=9 Hz); IR (nujol) 1700, 1580, 1305, 1255 cm⁻¹.

EXAMPLE 15 Preparation of2-[1,1-Dimethylethyl)Aminosulfonyl]-6-Methoxy-3-Pyridinecarboxylic Acid,Methyl Ester

To a vigorously stirred mixture of 3.7 g (0.0129 mol) of the productfrom Example 14 in 79 mL methylene chloride and 41 mL water cooled to 0°was added 6.3 mL (0.0759 mol) concentrated hydrochloric acid followed bythe dropwise addition of 79 mL (0.053 mol) of a 5% sodium hypochloritesolution such that the temperature was maintained below 5°. After themixture was stirred for an additional 30 minutes at 0° the reaction waspoured into water and extracted with methylene chloride. The combinedorganic layers were washed with brine, dried over magnesium sulfate, andfiltered. The filtrate was stirred and cooled to -70° under nitrogen,and 4.7 (0.0645 mol) of t-butyl amine was added dropwise. The reactionmixture was allowed to warm to -20°, poured into water, acidified with 1normal hydrochloric acid, and extracted with methylene chloride. Thecombined organic layers were washed with brine, dried over magnesiumsulfate, and evaporated to a semisolid which was purified by flashchromatography to afford 3.0 g (77%) yellow solid: m.p. 128°-130°; NMR(CDCl₃, 200 Mhz) 1.27 (9H, s), 3.94 (3H, s), 4.05 (3H, s) 5.75 (NH), 6.9(1H, d, J=9 Hz), 7.95 (1H, d, J=7 HZ); IR (nujol) 3260, 1740, 1605,1325, 1125 cm⁻¹.

EXAMPLE 16 Preparation of2-(Aminosulfonyl)-6-Methoxy-3-Pyridine-Carboxylic Acid, Methyl Ester

A solution of 2.9 g (0.0096 mol) of the product from Example 15 wasstirred in 50 mL trifluoroacetic acid at room temperature for 20 hours.The solution was evaporated to afford 2.4 g (100%) white solid: m.p.142.5°-144.5°; NMR (CDCl, 200 Mhz) 3.97 (3H, s), 4.1 (3H, s), 5.6 (NH₂),6.9 (1H, d, J=9 Hz), 8.1 (1H, d, J=9 Hz); IR (nujol) 3305, 3205, 1715,1590, 1355, 1320, 1175 cm⁻¹.

EXAMPLE 17 Preparation of 2-(4.6-Dimethoxypyrimidin-2-yl)aminocarbonyl]aminosulfonyl]-6-Methoxy-3-Pyridinecarboxylic Acid, MethylEster

To a stirred suspension of 0.4 g (0.0016 mol) of the product fromExample 16 and 0.54 g (0.002 mol) of phenyl(4,6-dimethoxypyrimidin-2-yl)carbamate in 4 mL acetonitrile was added dropwise 0.30 g (0.002 mol) of1,8-diazobicyclo[5.4.0]undec-7-ene and stirred for 30 minutes. Thesolution was diluted with water and acidified with 1 normal hydrochloricacid. The resulting precipitate was collected and washed with water andwith ether to afford 0.57 g (84%) white solid: m.p. 194°-196°; NMR(CDCl₃, 200 Mhz), 3.83 (3H, s), 3.95 (9H, s), 5.8 (1H, s), 6.95 (1H, d,J=9 Hz), 7.4 (NH), 8.1 (1H, d, J=9 Hz), 12.8 (NH); IR (nujol) 3140,1740, 1720, 1640, 1360, 1195, 1140 cm⁻¹.

EXAMPLE 18 Preparation ofN-(1,1-Dimethylethyl)-2-Fluoro-3-Pyridinesulfonamide

To a stirred solution of 396 mL (0.740 mol) of 1.9 molar lithiumdiisopropylamide (in hexanes) in 1.5 L dry tetrahydrofuran cooled to-70° under nitrogen was added dropwise a solution of 65 g (0.670 mol) of2-fluoropyridine in 150 mL dry tetrahydrofuran such that the temperaturewas maintained below -65°. The suspension was stirred at -70° foranother 3.5 hours and 86 g (1.34 mol) of sulfur dioxide was added whilemaintaining the temperature below -65°. After stirring another 15minutes at -70°, the reaction was allowed to warm to 0° and evaporatedto half the original volume and diluted with ether. The whiteprecipitate was collected under nitrogen, washed with ether, and dried.The solid was dissolved in 800 mL acetic acid and cooled to 10°-20°. Tothis stirred solution was added portionwise 99.4 g (0.740 mol) ofN-chlorosuccinimide while maintaining the temperature below 20°. Afterstirring another 30 minutes, the suspension was evaporated, diluted withwater and extracted with methylene chloride. The combined organic phaseswere washed with saturated aqueous sodium bicarbonate solution until nomore gas evolution, washed with brine, dried over magnesium sulfate, andfiltered. The filtrate was cooled to -70° under nitrogen and to thisstirred solution was added dropwise 199 g (2.7 mol) of t-butylamine. Thesuspension was poured into ice water, acidified with concentratedhydrochloric acid, and extracted with methylene chloride. The combinedorganic layers were washed with brine, dried over magnesium sulfate, andevaporated to an oil which was purified by flash chromatography toafford 29.1 g (19%) of a brown solid which was further washed with coldn-butylchloride to afford 22.4 g (14.5%) of a white solid: m.p. 95°-97°;NMR (CDCl₃, 200 Mhz) 1.25 (9H, s), 4.9 (NH), 7.35 (1H, m), 8.3-8.5 (2H,m).

EXAMPLE 19 Preparation ofN-(1,1-Dimethylethyl)-2-Fluoro-N-Methyl-3-Pyridinesulfonamide

To a stirred suspension of 3.4 g (0.071 mol) of 50% sodium hydride (inmineral oil), which had been washed with hexanes, in 120 mL drydimethyldormamide cooled to 0° under nitrogen was added dropwise asolution of 15.0 g (0.065 mol) of the product from Example 18 in 120 mLdry dimethylformamide. After stirring at room temperature for 1 hour,the mixture was cooled to 0° and 12.2 g (0.086 mol) of methyl iodide wasadded dropwise. After warming to room temperature the reaction waspoured into ice water and extracted with ether. The combined organiclayers were washed with brine, dried over magnesium sulfate, andevaporated to 15.9 g (99%) oil; NMR (CDCl₃, 200 MHz), 1.32 (9H, s), 3.1(3H, s), 7.3 (1H, m), 8.3-8.4 (2H, m); lR (neat) 1590, 1570, 1335, 1155cm⁻¹.

EXAMPLE 20 Preparation of N-(1,1-Dimethylethyl)-N-Methyl-2-(Phenylmethylthio)-3-Pyridinesulfonamide

Using the same procedure as in Example 14, 15.9 g (0.065 mol) of theproduct from Example 19 was converted to 19.5 g (86%) yellow solid: m.p.92°-94°; NMR (CDCl₃), 200 Mhz) 1.26 (9H, s), 3.1 (3H, s), 4.5 (2H, s),7.0-7.5 (6H, m), 8.2 (1H, m); IR (nujol) 1570, 1385, 1315, 1150, 1120cm⁻¹.

EXAMPLE 21 Preparation of N2,N3-Bis(1,1-Dimethylethyl)-N3-Methyl-2,3-Pyridinedisulfonamide

Using the same procedure as in Example 15, 19.5 g (0.056 mol) of theProduct from Example 20 was converted to a tan solid which was washedwith n-butylchloride to afford 13.1 g (66%) white solid: m.p.155°-156.5°; NMR (CDCl₃, 200 Mhz) 1.23 (9H, s), 1.33 (9H, s), 3.1 (3H,s), 6.0 (NH), 1H, m), 8.5 (1H, m), 8.8 (1H, m); lR (nujol) 3320, 1340,1325, 1160, 1120 cm⁻¹.

EXAMPLE 22 Preparation of N3-Methyl-2,3-Pyridinedisulfonamide

A stirred solution of 13.1 g (0.036 mol) of the product from Example 21in 150 mL trifluoroacetic acid was refluxed for 5 hours. After coolingto room temperature, the solution was evaporated to a solid which waswashed with ether to afford 9.6 g (100%) white solid: m.p. 220°-223°;NMR (DMSO-d₆, 200 Mhz), 2.5 (3H, d), 6.9 (NH), 7.65 (NH₂), 7.85 (1H, m),8.45 (1H, m), 8.9 (1H, m); IR (nujol) 3380, 3320, 3180, 1355, 1170 cm⁻¹.

EXAMPLE 23 Preparation ofN2-[(4,6-Dimethoxypyrimidin-2-yl)aminocarbonyl]-N3-Methyl-2,3-Pyridinedisulfonamide

To a stirred suspension of 4.15 g (0.0165 mol) of the product fromExample 22 and 5.0 g (0.018 mol) of phenyl(4,6-dimethoxypyrimidin-2-yl)carbamate in 50 mL acetonitrile was addeddropwise 2.8 g (0.018 mol) of 1,8-diazabicyclo[5.4.0]undec-4-end andstirred for 30 minutes. The solution was diluted with water andacidified with 1 normal hydrochloric acid. The resulting precipitate wascollected and washed with water and with ether to afford 6.4 g (82%)white solid: m.p. 147°-148.5°; NMR (CDCl₃, 200 MHz) 2.7 (3H, d, J=7 Hz),3.97 (6H, s), 5.8 (1H, s), 6.15 (1H, m), 7.3 (NH), 7.7 (1H, m), 8.55(1H, m), 8.8 (1H, m), 13.1 (NH); IR (nujol) 3310, 1740, 1610, 1340,1190, 1165 cm⁻¹.

By applying the procedures of Examples 1 through 23 and Equations 1through 19, the compounds in Tables I through X can be prepared by oneskilled in the art. ##STR54##

                                      TABLE I                                     __________________________________________________________________________    General Formula 1                                                             R.sub.1                                                                              R.sub.2     R  X     Y    Z  m.p. (°C.)                         __________________________________________________________________________    H      SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 170-174                                   H      SOCH.sub.3  H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 138-140                                   H      SOCH.sub.3  H  Cl    OCH.sub.3                                                                          CH 124-126                                   H      SOCH.sub.3  H  CH.sub.3                                                                            CH.sub.3                                                                           CH 126-127.5                                 H      SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      SOCH.sub.3  H  OCH.sub.3                                                                           CH.sub.3                                                                           N  165-167                                   H      SOCH.sub.3  H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SOCH.sub.3  CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N  133-137                                   4-CH.sub.3                                                                           SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 170-172                                   H      SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub. 3                                                                          CH 158-160                                   H      SO.sub.2 CH.sub.3                                                                         H  Cl    OCH.sub.3                                                                          CH 158-160                                   H      SO.sub.2 CH.sub.3                                                                         H  CH.sub.3                                                                            CH.sub.3                                                                           CH 162-164                                   H      SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  180-184                                   H      SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           N  154-156.5                                 H      SO.sub.2 CH.sub.3                                                                         H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 132-136                                   H      SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 141-144                                   H      SOCH.sub.2 CH.sub.3                                                                       H  Cl    OCH.sub.3                                                                          CH 105-107.5                                 H      SOCH.sub.2 CH.sub.3                                                                       H  CH.sub.3                                                                            CH.sub.3                                                                           CH 153- 156.5                                H      SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  154-158                                   H      SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           N  172-174                                   H      SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SOCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 160-162                                   H      SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 160-162                                   H      SO.sub.2 CH.sub.2 CH.sub.3                                                                H  Cl    OCH.sub.3                                                                          CH 163-164.5                                 H      SO.sub.2 CH.sub.2 CH.sub.3                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH 167-169                                   H      SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  155-158                                   H      SO.sub.2 CH.sub. 2 CH.sub.3                                                               H  OCH.sub.3                                                                           CH.sub.3                                                                           N  165.5-168                                 H      SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N  137-138                                   4-CH.sub.3                                                                           SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 178-180                                   6-CH.sub.3                                                                           SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 169.5-172                                 6-CH.sub.3                                                                           SO.sub.2 CH.sub.2 CH.sub.3                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH 172-173.5                                 6-CH.sub.3                                                                           SO.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N  133-135                                   6-OCH.sub.3                                                                          SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 210-213                                   6-F    SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 157-160                                   6-F    SO.sub.2 CH.sub.2 CH.sub.3                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH 176-177                                   6-Cl   SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 187-189                                   6-Cl   SO.sub.2 CH.sub. 2 CH.sub.3                                                               H  Cl    OCH.sub.3                                                                          CH 171-174                                   6-Cl   SO.sub.2 CH.sub.2 CH.sub.3                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH 181-182                                   6-SCH.sub.3                                                                          SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-SCH.sub.3                                                                          SO.sub.2 CH.sub.2 CH.sub.3                                                                H  Cl    OCH.sub.3                                                                          CH                                           5-CH.sub.3                                                                           SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 159-160                                   5-CH.sub.3                                                                           SO.sub.2 CH.sub.2 CH.sub.3                                                                H  Cl    OCH.sub.3                                                                          CH 176-177                                   5-CH.sub.3                                                                           SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  155-156                                   5-CH.sub.3                                                                           SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N  159-161                                   H      SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 111-115                                   H      SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 141-145                                   H      SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  Cl    OCH.sub.3                                                                          CH 111-113                                   H      SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  CH.sub.3                                                                            CH.sub.3                                                                           CH 173-175                                   H      SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  186-189                                   H      SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           CH.sub. 3                                                                          N  164-166                                   H      SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N  121-123                                   H      SOCH.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 168-170                                   H      SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 157-159                                   H      SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  Cl    OCH.sub.3                                                                          CH 165-167                                   H      SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  CH.sub.3                                                                            CH.sub.3                                                                           CH 158-160                                   H      SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  164- 166                                  H      SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           N  165-168                                   H      SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N  148-152                                   H      SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 144-147                                   H      SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 143-145.5                                 H      SOCH(CH.sub.3).sub.2                                                                      H  Cl    OCH.sub.3                                                                          CH 133-135                                   H      SOCH(CH.sub.3).sub.2                                                                      H  CH.sub.3                                                                            CH.sub.3                                                                           CH 150-153                                   H      SOCH(CH.sub. 3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  155-159                                   H      SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           N  150-153                                   H      SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SOCH(CH.sub.3).sub.2                                                                      CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 140-146                                   H      SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           CH   CH 159-160.5                                 H      SO.sub.2 CH(CH.sub.3).sub.2                                                               H  Cl    OCH.sub.3                                                                          CH 164-165.5                                 H      SO.sub.2 CH(CH.sub.3).sub.2                                                               H  CH.sub.3                                                                            CH.sub.3                                                                           CH 161-163                                   H      SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  164-166                                   H      SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           CH.sub.3                                                                           N  165-167                                   H      SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 CH(CH.sub.3).sub.2                                                               CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N  145-149                                   4-CH.sub.3                                                                           SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  Cl    OCH.sub.3                                                                          CH                                           H      SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      SOCH.sub.2 CH.sub.2 CH.sub. 2 CH.sub.3                                                    H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 155-157                                   H      SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 142-144                                   H      SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  Cl    OCH.sub.3                                                                          CH 151-153                                   H      SO.sub.2 CH.sub.2 CH.sub.2 CH.sub. 2 CH.sub.3                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH 142-143                                   H      SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  153.5-155                                 H      SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           N  142.5-145.5                               H      SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                          N  133-136                                   4-CH.sub.3                                                                           SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      S-cyclopropyl                                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      S-cyclopropyl                                                                             H  Cl    OCH.sub.3                                                                          CH                                           H      S-cyclopropyl                                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      S-cyclopropyl                                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      S-cyclopropyl                                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      S-cyclopropyl                                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      SO-cyclopropyl                                                                            H  Cl    OCH.sub.3                                                                          CH                                           H      SO-cyclopropyl                                                                            H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      SO-cyclopropyl                                                                            H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO-cyclopropyl                                                                            CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      SO.sub.2 -cyclopropyl                                                                     H  Cl    OCH.sub.3                                                                          CH                                           H      SO.sub.2 -cyclopropyl                                                                     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 -cyclopropyl                                                                     CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 169-171                                   H      OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 172-173.5                                 H      OSO.sub.2 CH.sub.3                                                                        H  Cl    OCH.sub.3                                                                          CH 171-173                                   H      OSO.sub.2 CH.sub.3                                                                        H  CH.sub.3                                                                            CH.sub.3                                                                           CH 161.5-165                                 H      OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           CH.sub.3                                                                           N  155-158                                   H      OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      OSO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 162-163.5                                 H      OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 160-162                                   H      OSO.sub.2 CH.sub.2 CH.sub. 3                                                              H  Cl    OCH.sub.3                                                                          CH 139-143                                   H      OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  CH.sub.3                                                                            CH.sub.3                                                                           CH 132-138                                   H      OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  171.5-173                                 H      OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           CH.sub.3                                                                           N  147-149                                   H      OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      OSO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 156-157                                   H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 131-133                                   H      OSO.sub. 2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  Cl    OCH.sub.3                                                                          CH 127-132                                   H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  CH.sub.3                                                                            CH.sub.3                                                                           CH 152-153                                   H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  154-155                                   H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      OSO.sub.2 CH(CH.sub.3).sub.2                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      OSO.sub.2 CH(CH.sub.3).sub.2                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      OSO.sub.2 CH(CH.sub.3).sub.2                                                              H  Cl    OCH.sub.3                                                                          CH                                           H      OSO.sub.2 CH(CH.sub.3).sub.2                                                              H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      OSO.sub.2 CH(CH.sub.3).sub.2                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      OSO.sub.2 CH(CH.sub.3).sub.2                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      OSO.sub.2 CH(CH.sub.3).sub.2                                                              H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      OSO.sub.2 CH(CH.sub.3).sub.2                                                              CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           OSO.sub.2 CH(CH.sub.3).sub.2                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          OSO.sub.2 CH(CH.sub.3).sub.2                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           OSO.sub.2 CH(CH.sub.3).sub.2                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          OSO.sub.2 CH(CH.sub.3).sub.2                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    OSO.sub.2 CH(CH.sub.3).sub.2                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   OSO.sub.2 CH(CH.sub.3).sub.2                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                             H  Cl    OCH.sub.3                                                                          CH                                           H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 140-142                                   H      OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      OSO.sub.2 CF.sub.3                                                                        H  Cl    OCH.sub.3                                                                          CH 154-156                                   H      OSO.sub.2 CF.sub.3                                                                        H  CH.sub.3                                                                            CH.sub.3                                                                           CH 157-160                                   H      OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  164-166                                   H      OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           CH.sub.3                                                                           N  157-159                                   H      OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      OSO.sub.2 CF.sub.3                                                                        CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      OSO.sub.2 CCl.sub.3                                                                       H  Cl    OCH.sub.3                                                                          CH                                           H      OSO.sub.2 CCl.sub.3                                                                       H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      OSO.sub.2 CCl.sub.3                                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                   H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                   H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                   H  Cl    OCH.sub.3                                                                          CH                                           H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                   H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                   H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                   H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                   H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                   CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                   H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                   H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                   H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                   H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                   H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                   H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  Cl    OCH.sub.3                                                                          CH                                           H      SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 OCH.sub.2 CF.sub.3                                                               CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 OCH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 OCH.sub.3                                                                        H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      SO.sub.2 OCH.sub.3                                                                        H  Cl    OCH.sub. 3                                                                         CH                                           H      SO.sub.2 OCH.sub.3                                                                        H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      SO.sub.2 OCH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      SO.sub.2 OCH.sub.3                                                                        H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      SO.sub.2 OCH.sub.3                                                                        H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 OCH.sub.3                                                                        CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SO.sub.2 OCH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 OCH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 OCH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 OCH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 OCH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 OCH                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 OCH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 OCH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      SO.sub.2 OCH.sub.2 CH.sub.3                                                               H  Cl    OCH.sub.3                                                                          CH                                           H      SO.sub.2 OCH.sub.2 CH.sub.3                                                               H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      SO.sub.2 OCH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      SO.sub.2 OCH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      SO.sub.2 OCH.sub.2 CH.sub.3                                                               H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 OCH.sub.2 CH.sub.3                                                               CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SO.sub.2 OCH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 OCH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 OCH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 OCH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 OCH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 OCH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      N.sub.3     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      N.sub.3     H  Cl    OCH.sub.3                                                                          CH                                           H      N.sub.3     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      N.sub.3     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      N.sub.3     H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      N.sub.3     CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CN          H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      CN          H  Cl    OCH.sub.3                                                                          CH                                           H      CN          H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      CN          H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      CN          H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      CN          CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      P(O)(OCH.sub.3).sub.2                                                                     H  Cl    OCH.sub.3                                                                          CH                                           H      P(O)(OCH.sub.3).sub.2                                                                     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      P(O)(OCH.sub.3).sub.2                                                                     CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      P(O)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 108-111                                   H      P(O)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      P(O)(OCH.sub.2 CH.sub.3).sub.2                                                            H  Cl    OCH.sub.3                                                                          CH                                           H      P(O)(OCH.sub.2 CH.sub.3).sub.2                                                            H  CH.sub.3                                                                            CH.sub.3                                                                           CH 110-114                                   H      P(O)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      P(O)(OCH.sub.2 CH.sub.3 ).sub.2                                                           H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      P(O)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      P(O)(OCH.sub.2 CH.sub.3).sub.2                                                            CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           P(O)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          P(O)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           P(O)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          P(O)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    P(O)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   P(O)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      P(S)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      P(S)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      P(S)(OCH.sub.3).sub.2                                                                     H  Cl    OCH.sub.3                                                                          CH                                           H      P(S)(OCH.sub.3).sub.2                                                                     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      P(S)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      P(S)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      P(S)(OCH.sub.3).sub.2                                                                     H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      P(S)(OCH.sub.3 ).sub.2                                                                    CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           P(S)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          P(S)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           P(S)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          P(S)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    P(S)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   P(S)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      P(S)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      P(S)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      P(S)(OCH.sub.2 CH.sub.3).sub.2                                                            H  Cl    OCH.sub.3                                                                          CH                                           H      P(S)(OCH.sub.2 CH.sub.3).sub.2                                                            H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      P(S)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      P(S)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      P(S)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      P(S)(OCH.sub.2 CH.sub.3).sub.2                                                            CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           P(S)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub. 3                                                                         P(S)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           P(S)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          P(S)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    P(S)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   P(S)(OCH.sub.2 CH.sub.3).sub.2                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CH.sub.2 F  H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      CH.sub.2 F  H  Cl    OCH.sub.3                                                                          CH                                           H      CH.sub.2 F  H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      CH.sub.2 F  H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      CH.sub.2 F  H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      CH.sub.2 F  CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CF.sub.2 H  H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      CF.sub.2 H  H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      CF.sub.2 H  H  Cl    OCH.sub.3                                                                          CH                                           H      CF.sub.2 H  H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      CF.sub.2 H  H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      CF.sub.2 H  H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      CF.sub.2 H  CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           CF.sub.2 H  H  CH.sub.3                                                                            OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CH.sub.2 Cl H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CH.sub.2 Cl H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      CH.sub.2 Cl H  Cl    OCH.sub.3                                                                          CH                                           H      CH.sub.2 Cl H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      CH.sub. 2 Cl                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      CH.sub.2 Cl H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      CH.sub.2 Cl H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      CH.sub.2 Cl CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           CH.sub.2 Cl H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          CH.sub.2 Cl H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           CH.sub.2 Cl H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          CH.sub.2 Cl H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    CH.sub.2 Cl H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   CH.sub.2 Cl H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CCl.sub.2 H H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CCl.sub.2 H H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      CCl.sub.2 H H  Cl    OCH.sub.3                                                                          CH                                           H      CCl.sub.2 H H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      CCl.sub.2 H H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      CCl.sub.2 H H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      CCl.sub.2 H H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      CCl.sub.2 H CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           CCl.sub.2 H H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          CCl.sub.2 H H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           CCl.sub.2 H H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          CCl.sub.2 H H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    CCl.sub.2 H H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   CCl.sub.2 H H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CH.sub.2 CH.sub.2 Cl                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CH.sub.2 CH.sub.2 Cl                                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      CH.sub.2 CH.sub.2 Cl                                                                      H  Cl    OCH.sub.3                                                                          CH                                           H      CH.sub.2 CH.sub.2 Cl                                                                      H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      CH.sub.2 CH.sub.2 Cl                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      CH.sub.2 CH.sub.2 Cl                                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      CH.sub.2 CH.sub.2 Cl                                                                      H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      CH.sub.2 CH.sub.2 Cl                                                                      CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           CH.sub.2 CH.sub.2 Cl                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          CH.sub.2 CH.sub.2 Cl                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           CH.sub.2 CH.sub.2 Cl                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          CH.sub.2 CH.sub.2 Cl                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    CH.sub.2 CH.sub.2 Cl                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   CH.sub.2 CH.sub.2 Cl                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CH.sub.2 CH.sub.2 Br                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CH.sub.2 CH.sub.2 Br                                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      CH.sub.2 CH.sub.2 Br                                                                      H  Cl    OCH.sub.3                                                                          CH                                           H      CH.sub.2 CH.sub.2 Br                                                                      H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      CH.sub.2 CH.sub.2 Br                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      CH.sub.2 CH.sub.2 Br                                                                      F  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      CH.sub.2 CH.sub.2 Br                                                                      H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      CH.sub.2 CH.sub.2 Br                                                                      CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           CH.sub.2 CH.sub.2 Br                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          CH.sub.2 CH.sub.2 Br                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           CH.sub.2 CH.sub.2 Br                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          CH.sub.2 CH.sub.2 Br                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    CH.sub.2 CH.sub.2 Br                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   CH.sub.2 CH.sub.2 Br                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CHFCH.sub.3 H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CHFCH.sub.3 H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      CHFCH.sub.3 H  Cl    OCH.sub.3                                                                          CH                                           H      CHFCH.sub.3 H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      CHFCH.sub.3 H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      CHFCH.sub.3 H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      CHFCH.sub.3 H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      CHFCH.sub.3 CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           CHFCH.sub.3 H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          CHFCH.sub.3 H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           CHFCH.sub.3 H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          CHFCH.sub.3 H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    CHFCH.sub.3 H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   CHFCH.sub.3 H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CHClCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CHClCH.sub.3                                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      CHClCH.sub.3                                                                              H  Cl    OCH.sub.3                                                                          CH                                           H      CHClCH.sub.3                                                                              H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      CHClCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      CHClCH.sub.3                                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      CHClCH.sub.3                                                                              H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      CHClCH.sub.3                                                                              CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           CHClCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          CHClCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           CHClCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          CHClCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    CHClCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   CHClCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CF.sub.2 CF.sub.2 H                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CF.sub.2 CF.sub.2 H                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      CF.sub.2 CF.sub.2 H                                                                       H  Cl    OCH.sub.3                                                                          CH                                           H      CF.sub.2 CF.sub.2 H                                                                       H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      CF.sub.2 CF.sub.2 H                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      CF.sub.2 CF.sub.2 H                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      CF.sub.2 CF.sub.2 H                                                                       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      CF.sub.2 CF.sub.2 H                                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           CF.sub.2 CF.sub.2 H                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          CF.sub.2 CF.sub.2 H                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           CF.sub.2 CF.sub.2 H                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          CF.sub.2 CF.sub.2 H                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    CF.sub.2 CF.sub.2 H                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   CF.sub.2 CF.sub.2 H                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.2 CH.sub.3                                                                  SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.2 CH.sub.3                                                                  SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-CH.sub.2 CH.sub.3                                                                  SO.sub.2 N(CH.sub.3).sub.2                                                                H  Cl    OCH.sub.3                                                                          CH                                           6-CH.sub.2 CH.sub.3                                                                  SO.sub.2 N(CH.sub.3).sub.2                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-CH.sub.2 CH.sub.3                                                                  SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-CH.sub.2 CH.sub.3                                                                  SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-CH.sub.2 CH.sub.3                                                                  SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-CH.sub.2 CH.sub.3                                                                  SO.sub.2 N(CH.sub.3).sub.2                                                                CH.sub.3                                                                         OCH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                           N                                            6-OCH.sub.3                                                                          SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 N(CH.sub.3).sub.2                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-OCH.sub.3                                                                          SO.sub. 2 N(CH.sub.3).sub.2                                                               H  Cl    OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 N(CH.sub.3).sub.2                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-OCH.sub.3                                                                          SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-OCH.sub.3                                                                          SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCH.sub.3                                                                          SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-OCH.sub.3                                                                          SO.sub.2 N(CH.sub.3).sub.2                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCH.sub.2 CH.sub.3                                                                 SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.2 CH.sub.3                                                                 SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-OCH.sub.2 CH.sub.3                                                                 SO.sub.2 N(CH.sub.3).sub.2                                                                H  Cl    OCH.sub.3                                                                          CH                                           6-OCH.sub.2 CH.sub.3                                                                 SO.sub.2 N(CH.sub.3).sub.2                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-OCH.sub.2 CH.sub.3                                                                 SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-OCH.sub.2 CH.sub.3                                                                 SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCH.sub.2 CH.sub.3                                                                 SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-OCH.sub.2 CH.sub.3                                                                 SO.sub.2 N(CH.sub.3).sub.2                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.2 CH.sub.3                                                                 SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-SCH.sub.2 CH.sub.3                                                                 SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-SCH.sub.2 CH.sub.3                                                                 SO.sub.2 N(CH.sub.3).sub.2                                                                H  Cl    OCH.sub.3                                                                          CH                                           6-SCH.sub.2 CH.sub.3                                                                 SO.sub.2 N(CH.sub.3).sub.2                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-SCH.sub.2 CH.sub.3                                                                 SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-SCH.sub.2 CH.sub.3                                                                 SO.sub.2 N(CH.sub.3 .sub.2                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.2 CH.sub.3                                                                 SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-SCH.sub.2 CH.sub.3                                                                 SO.sub.2 N(CH.sub.3).sub.2                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.3                                                                          SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-SCH.sub.3                                                                          SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-SCH.sub.3                                                                          SO.sub.2 N(CH.sub.3).sub.2                                                                H  Cl    OCH.sub.3                                                                          CH                                           6-SCH.sub.3                                                                          SO.sub.2 N(CH.sub.3).sub.2                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-SCH.sub.3                                                                          SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-SCH.sub.3                                                                          SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.3                                                                          SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-SCH.sub.3                                                                          SO.sub.2 N(CH.sub.3).sub.2                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-N(CH.sub.3).sub.2                                                                  SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-N(CH.sub.3).sub.2                                                                  SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-N(CH.sub.3).sub.2                                                                  SO.sub.2 N(CH.sub.3).sub.2                                                                H  Cl    OCH.sub.3                                                                          CH                                           6-N(CH.sub.3).sub.2                                                                  SO.sub.2 N(CH.sub.3).sub.2                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-N(CH.sub.3).sub.2                                                                  SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-N(CH.sub.3).sub.2                                                                  SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-N(CH.sub.3).sub.2                                                                  SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-N(CH.sub.3).sub.2                                                                  SO.sub.2 N(CH.sub.3).sub.2                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-NHCH.sub.3                                                                         SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-NHCH.sub.3                                                                         SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-NHCH.sub.3                                                                         SO.sub.2 N(CH.sub.3).sub.2                                                                H  Cl    OCH.sub.3                                                                          CH                                           6-NHCH.sub.3                                                                         SO.sub.2 N(CH.sub.3).sub.2                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-NHCH.sub.3                                                                         SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-NHCH.sub.3                                                                         SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-NHCH.sub.3                                                                         SO.sub.2 N(CH.sub.3).sub.2                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-NHCH.sub.3                                                                         SO.sub.2 N(CH.sub.3).sub.2                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCH.sub.3                                                                          SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-OCH.sub.3                                                                          SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  Cl    OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-OCH.sub.3                                                                          SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-OCH.sub.3                                                                          SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCH.sub.3                                                                          SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-OCH.sub.3                                                                          SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.3                                                                          SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-SCH.sub.3                                                                          SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-SCH.sub.3                                                                          SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  Cl    OCH.sub.3                                                                          CH                                           6-SCH.sub.3                                                                          SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-SCH.sub.3                                                                          SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-SCH.sub.3                                                                          SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.3                                                                          SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-SCH.sub.3                                                                          SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-N(CH.sub.3).sub.2                                                                  SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-N(CH.sub.3).sub.2                                                                  SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-N(CH.sub.3).sub. 2                                                                 SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  Cl    OCH.sub.3                                                                          CH                                           6-N(CH.sub.3).sub.2                                                                  SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-N(CH.sub.3).sub.2                                                                  SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-N(CH.sub.3).sub.2                                                                  SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-N(CH.sub.3).sub.2                                                                  SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-N(CH.sub.3).sub.2                                                                  SO.sub.2 N(CH.sub.2 CH.sub.3).sub.2                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.3                                                                          SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-SCH.sub.3                                                                          SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-SCH.sub.3                                                                          SO.sub.2 NHOCH.sub.3                                                                      H  Cl    OCH.sub.3                                                                          CH                                           6-SCH.sub.3                                                                          SO.sub.2 NHOCH.sub.3                                                                      H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-SCH.sub.3                                                                          SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-SCH.sub.3                                                                          SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.3                                                                          SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-SCH.sub.3                                                                          SO.sub.2 NHOCH.sub.3                                                                      CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.2 CH.sub.3                                                                 SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-SCH.sub.2 CH.sub.3                                                                 SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-SCH.sub.2 CH.sub.3                                                                 SO.sub.2 NHOCH.sub.3                                                                      H  Cl    OCH.sub.3                                                                          CH                                           6-SCH.sub.2 CH.sub.3                                                                 SO.sub.2 NHOCH.sub.3                                                                      H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-SCH.sub.2 CH.sub.3                                                                 SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-SCH.sub.2 CH.sub.3                                                                 SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.2 CH.sub.3                                                                 SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-SCH.sub.2 CH.sub.3                                                                 SO.sub.2 NHOCH.sub.3                                                                      CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-N(CH.sub.3).sub.2                                                                  SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-N(CH.sub.3).sub.2                                                                  SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-N(CH.sub.3).sub.2                                                                  SO.sub.2 NHOCH.sub.3                                                                      H  Cl    OCH.sub.3                                                                          CH                                           6-N(CH.sub.3).sub.2                                                                  SO.sub.2 NHOCH.sub.3                                                                      H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-N(CH.sub.3).sub.2                                                                  SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-N(CH.sub.3).sub.2                                                                  SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.3                                                                           CH.sub. 3                                                                          N                                            6-N(CH.sub.3).sub.2                                                                  SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-N(CH.sub.3).sub.2                                                                  SO.sub.2 NHOCH.sub.3                                                                      CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCH.sub.3                                                                          SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-OCH.sub.3                                                                          SO.sub.2 NHOCH.sub.3                                                                      H  Cl    OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 NHOCH.sub.3                                                                      H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-OCH.sub.3                                                                          SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-OCH.sub.3                                                                          SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCH.sub.3                                                                          SO.sub.2 NHOCH.sub.3                                                                      H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-OCH.sub.3                                                                          SO.sub.2 NHOCH.sub.3                                                                      CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.3                                                                       H  Cl    OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.3                                                                       H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub. 3                                                                          N                                            6-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.3                                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.3                                                                          SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-SCH.sub.3                                                                          SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-SCH.sub.3                                                                          SO.sub.2 NHCH.sub.3                                                                       H  Cl    OCH.sub.3                                                                          CH                                           6-SCH.sub.3                                                                          SO.sub.2 NHCH.sub.3                                                                       H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-SCH.sub.3                                                                          SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-SCH.sub.3                                                                          SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.3                                                                          SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-SCH.sub.3                                                                          SO.sub.2 NHCH.sub.3                                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 147-148.5                                 H      SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      SO.sub.2 NHCH.sub.3                                                                       H  Cl    OCH.sub.3                                                                          CH 155-157                                   H      SO.sub.2 NHCH.sub.3                                                                       H  CH.sub.3                                                                            CH.sub.3                                                                           CH 150-152                                   H      SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           N  153.5-155                                 H      SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 NHCH.sub.3                                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 163-165.5                                 H      SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  Cl    OCH.sub.3                                                                          CH 158.5-161                                 H      SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  CH.sub.3                                                                            CH.sub.3                                                                           CH 118-121.5                                 H      SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  162-164                                   H      SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           N  158-160                                   H      SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 NHCH.sub.2 CH.sub.3                                                              CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N  122- 125.5                                4-CH.sub.3                                                                           SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 138.5-141                                 H      SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 117-120                                   H      SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  Cl    OCH.sub.3                                                                          CH 125-129                                   H      SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  132-135                                   H      SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 164-166                                   H      SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH.sub.3                                     H      SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  Cl    OCH.sub.3                                                                          CH 153.5-156                                 H      SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  149-152                                   H      SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  149-151                                   H      SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 NHCH(CH.sub.3).sub.2                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N  141-143                                   4-CH.sub.3                                                                           SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHcyclopropyl                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHcyclopropyl                                                                    H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      SO.sub.2 NHcyclopropyl                                                                    H  Cl    OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHcyclopropyl                                                                    H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      SO.sub.2 NHcyclopropyl                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      SO.sub.2 NHcyclopropyl                                                                    H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      SO.sub.2 NHcyclopropyl                                                                    H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 NHcyclopropyl                                                                    CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SO.sub.2 NHcyclopropyl                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub. 3                                                                         SO.sub.2 NHcyclopropyl                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 NHcyclopropyl                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 NHcyclopropyl                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 NHcyclopropyl                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 NHcyclopropyl                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  CL    OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 C.tbd.CH                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 C.tbd.CH                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      SO.sub.2 NHCH.sub.2 C.tbd.CH                                                              H  Cl    OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 C.tbd.CH                                                              H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      SO.sub.2 NHCH.sub.2 C.tbd.CH                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      SO.sub.2 NHCH.sub.2 C.tbd.CH                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      SO.sub.2 NHCH.sub.2 C.tbd.CH                                                              H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 NHCH.sub.2 C.tbd.CH                                                              CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SO.sub.2 NHCH.sub.2 C.tbd.CH                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.2 C.tbd.CH                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 NHCH.sub.2 C.tbd.CH                                                              H  OCH.sub.3                                                                           OCH.sub. 3                                                                         CH                                           6-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.2 C.tbd.CH                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 NHCH.sub.2 C.tbd.CH                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 NHCH.sub.2 C.tbd.CH                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 OCH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 OCH.sub.3                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      SO.sub.2 NHCH.sub.2 OCH.sub.3                                                             H  CL    OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 OCH.sub.3                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      SO.sub.2 NHCH.sub.2 OCH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      SO.sub.2 NHCH.sub.2 OCH.sub.3                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      SO.sub.2 NHCH.sub.2 OCH.sub.3                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 NHCH.sub.2 OCH.sub.3                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SO.sub.2 NHCH.sub.2 OCH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.2 OCH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 NHCH.sub.2 OCH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.2 OCH.sub.3                                                             H  OCH.sub. 3                                                                          OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 NHCH.sub.2 OCH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 NHCH.sub.2 OCH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  Cl    OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 NHCH.sub.2 CF.sub.3                                                              CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      SO.sub.2 NHCH.sub.2 CN                                                                    H  CL    OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 CN                                                                    H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 NHCH.sub.2 CN                                                                    CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub. 2                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  Cl    OCH.sub.3                                                                          CH                                           H      SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      SO.sub.2 -pyrrolidino                                                                     H  CL    OCH.sub.3                                                                          CH                                           H      SO.sub.2 -pyrrolidino                                                                     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 -pyrrolidino                                                                     CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  Cl    OCH.sub.3                                                                          CH                                           H      SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 146-149                                   H      SO.sub.2 -pyrrolidino                                                                     H  CH.sub.3                                                                            CH.sub.3                                                                           CH 169- 171                                  6-CH.sub.2 CH.sub.3                                                                  CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.2 CH.sub.3                                                                  CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-CH.sub.2 CH.sub.3                                                                  CO.sub.2 CH.sub.3                                                                         H  Cl    OCH.sub.3                                                                          CH                                           6-CH.sub.2 CH.sub.3                                                                  CO.sub.2 CH.sub.3                                                                         H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-CH.sub.2 CH.sub.3                                                                  CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-CH.sub.2 CH.sub.3                                                                  CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-CH.sub.2 CH.sub.3                                                                  CO.sub.2 CH.sub.3                                                                         H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-CH.sub.2 CH.sub.3                                                                  CO.sub.2 CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 194-196                                   6-OCH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 165-167                                   6-OCH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  Cl    OCH.sub.3                                                                          CH 173-175                                   6-OCH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  CH.sub.3                                                                            CH.sub.3                                                                           CH 138.5-145                                 6-OCH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  173-176                                   6-OCH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           N  158-161                                   6-OCH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-OCH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 154-157                                   6-OCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 160-162                                   6-OCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  Cl    OCH.sub.3                                                                          CH 130-132                                   6-OCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  CH.sub.3                                                                            CH.sub.3                                                                           CH 140-141                                   6-OCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  160-162                                   6-OCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           N  152-153                                   6-OCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-OCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCF.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCF.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-OCF.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  Cl    OCH.sub.3                                                                          CH                                           6-OCF.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-OCF.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-OCF.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCH.sub.2 CF.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 158-162                                   6-OCH.sub.2 CF.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 168-170                                   6-OCH.sub.2 CF.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  Cl    OCH.sub.3                                                                          CH 149-150                                   6-OCH.sub.2 CF.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  CH.sub.3                                                                            CH.sub.3                                                                           CH 150-152                                   6-OCH.sub.2 CF.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-OCH.sub.2 CF.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCH.sub.2 CF.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-OCH.sub.2 CF.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCF.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-OCF.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCF.sub.2 H                                                                        CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCF.sub.2 H                                                                        CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-OCF.sub.2 H                                                                        CO.sub.2 CH.sub.3                                                                         H  Cl    OCH.sub.3                                                                          CH                                           6-OCF.sub.2 H                                                                        CO.sub.2 CH.sub.3                                                                         H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-OCF.sub.2 H                                                                        CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-OCF.sub.2 H                                                                        CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCF.sub.2 H                                                                        CO.sub.2 CH.sub.3                                                                         H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-OCF.sub.2 H                                                                        CO.sub.2 CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-SCH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-SCH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  Cl    OCH.sub.3                                                                          CH                                           6-SCH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-SCH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-SCH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-SCH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-SCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-SCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  Cl    OCH.sub.3                                                                          CH                                           6-SCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-SCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-SCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-SCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-N(CH.sub.3).sub.2                                                                  CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 164-167                                   6-N(CH.sub.3).sub.2                                                                  CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 178-179                                   6-N(CH.sub.3).sub.2                                                                  CO.sub.2 CH.sub.3                                                                         H  Cl    OCH.sub.3                                                                          CH 147-150                                   6-N(CH.sub.3).sub.2                                                                  CO.sub.2 CH.sub.3                                                                         H  CH.sub.3                                                                            CH.sub.3                                                                           CH 164-165                                   6 N(CH.sub.3).sub.2                                                                  CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  171-172                                   6-N(CH.sub.3).sub.2                                                                  CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           N  132-134                                   6-N(CH.sub.3).sub.2                                                                  CO.sub.2 CH.sub.3                                                                         H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N  152-155                                   6-N(CH.sub.3).sub.2                                                                  CO.sub.2 CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-NHCH.sub.3                                                                         CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-NHCH.sub.3                                                                         CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-NHCH.sub.3                                                                         CO.sub.2 CH.sub.3                                                                         H  Cl    OCH.sub.3                                                                          CH                                           6-NHCH.sub.3                                                                         CO.sub.2 CH.sub.3                                                                         H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-NHCH.sub.3                                                                         CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-NHCH.sub.3                                                                         CO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-NHCH.sub.3                                                                         CO.sub.2 CH.sub.3                                                                         H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-NHCH.sub.3                                                                         CO.sub.2 CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-CH.sub.2 CH.sub.3                                                                  CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.2 CH.sub.3                                                                  CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-CH.sub.2 CH.sub.3                                                                  CO.sub.2 CH.sub.2 CH.sub.3                                                                H  Cl    OCH.sub.3                                                                          CH                                           6-CH.sub.2 CH.sub.3                                                                  CO.sub.2 CH.sub.2 CH.sub.3                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-CH.sub.2 CH.sub.3                                                                  CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-CH.sub.2 CH.sub.3                                                                  CO.sub. 2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-CH.sub.2 CH.sub.3                                                                  CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-CH.sub.2 CH.sub.3                                                                  CO.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 158-161                                   6-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 147-149                                   6-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  Cl    OCH.sub.3                                                                          CH 124-127                                   6-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH 149-151                                   6-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  164-165                                   6-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N  131-132                                   6-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 152-154                                   6-OCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 134-135                                   6-OCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  Cl    OCH.sub.3                                                                          CH 153-160                                   6-OCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH 159-163                                   6-OCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  320-330                                   6-OCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-OCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCH.sub.2 CF.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 173-175                                   6-OCH.sub.2 CF.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 166-167                                   6-OCH.sub.2 CF.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  Cl    OCH.sub.3                                                                          CH 150-152                                   6-OCH.sub.2 CF.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH 142-144                                   6-OCH.sub.2 CF.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  138- 141                                  6-OCH.sub.2 CF.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N  122-126                                   6-OCH.sub.2 CF.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-OCH.sub.2 CF.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCF.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCF.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-OCF.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  Cl    OCH.sub.3                                                                          CH                                           6-OCF.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-OCF.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-OCF.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCF.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-OCF.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCF.sub.2 H                                                                        CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCF.sub.2 H                                                                        CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-OCF.sub.2 H                                                                        CO.sub.2 CH.sub.2 CH.sub.3                                                                H  Cl    OCH.sub.3                                                                          CH                                           6-OCF.sub.2 H                                                                        CO.sub.2 CH.sub.2 CH.sub.3                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-OCF.sub.2 H                                                                        CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-OCF.sub.2 H                                                                        CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-OCF.sub.2 H                                                                        CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-OCF.sub.2 H                                                                        CO.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-SCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-SCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  Cl    OCH.sub.3                                                                          CH                                           6-SCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-SCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-SCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-SCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-SCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           6-SCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  Cl    OCH.sub.3                                                                          CH                                           6-SCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-SCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-SCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-SCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-SCH.sub.2 CH.sub.3                                                                 CO.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-N(CH.sub.3).sub.2                                                                  CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 147-149                                   6-N(CH.sub.3).sub.2                                                                  CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 149-150                                   6-N(CH.sub.3).sub.2                                                                  CO.sub.2 CH.sub.2 CH.sub.3                                                                H  Cl    OCH.sub.3                                                                          CH 150-151                                   6-N(CH.sub.3).sub.2                                                                  CO.sub.2 CH.sub.2 CH.sub.3                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH 172-175                                   6-N(CH.sub.3).sub.2                                                                  CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  152-153                                   6-N(CH.sub.3).sub.2                                                                  CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N  148-150                                   6-N(CH.sub.3).sub.2                                                                  CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-N(CH.sub.3).sub.2                                                                  CO.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-NHCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-NHCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH   CH                                           6-NHCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                                H  Cl    OCH.sub.3                                                                          CH                                           6-NHCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           6-NHCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            6-NHCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            6-NHCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            6-NHCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  Cl    OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  Cl    OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  Cl    OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CF.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CF.sub.3                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CF.sub.3                                             H  Cl    OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CF.sub.3                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CF.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CF.sub.3                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CF.sub.3                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CF.sub.3                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CF.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CF.sub. 3                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CF.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CF.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CF.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CF.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      CO.sub.2 CH.sub.2 CF.sub.3                                                                H  Cl    OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CF.sub.3                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      CO.sub.2 CH.sub.2 CF.sub.3                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          CO.sub. 2 CH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 C.tbd.CH                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 127-128                                   H      CO.sub.2 CH.sub.2 C.tbd.CH                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH 142-144                                   H      CO.sub.2 CH.sub.2 C.tbd.CH                                                                H  Cl    OCH.sub.3                                                                          CH 154-156                                   H      CO.sub.2 CH.sub.2 C.tbd.CH                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH 141-142                                   H      CO.sub.2 CH.sub.2 C.tbd.CH                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  137-138                                   H      CO.sub.2 CH.sub.2 C.tbd.CH                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N  136-137                                   H      CO.sub.2 CH.sub.2 C.tbd.CH                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      CO.sub.2 CH.sub.2 C.tbd.CH                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           CO.sub.2 CH.sub.2 C.tbd.CH                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          CO.sub. 2 CH.sub.2 C.tbd.CH                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           CO.sub.2 CH.sub.2 C.tbd.CH                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 C.tbd.CH                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    CO.sub.2 CH.sub.2 C.tbd.CH                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   CO.sub.2 CH.sub.2 C.tbd.CH                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                    H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                    H  Cl    OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                    H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                    H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                    H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                    CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           CO.sub.2 CH.sub. 2 CH.sub.2 CH.sub.2 Cl                                                   H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   CO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 Cl                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 SCH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 SCH.sub.3                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 SCH.sub.3                                                      H  Cl    OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 SCH.sub.3                                                      H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                           H      CO.sub.2 CH.sub.2 CH.sub.2 SCH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                            H      CO.sub.2 CH.sub.2 CH.sub.2 SCH.sub.3                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                            H      CO.sub.2 CH.sub.2 CH.sub.2 SCH.sub.3                                                      H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                            H      CO.sub.2 CH.sub.2 CH.sub.2 SCH.sub.3                                                      CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                            4-CH.sub.3                                                                           CO.sub.2 CH.sub.2 CH.sub.2 SCH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           4-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.2 SCH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-CH.sub.3                                                                           CO.sub.2 CH.sub.2 CH.sub.2 SCH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-OCH.sub.3                                                                          CO.sub.2 CH.sub.2 CH.sub.2 SCH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-F    CO.sub.2 CH.sub.2 CH.sub.2 SCH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           6-Cl   CO.sub.2 CH.sub.2 CH.sub.2 SCH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                           H      CO.sub.2 CH.sub.2 -cyclopropyl                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH 143-145                                   H      CO.sub.2 CH.sub.2 -cyclopropyl                                                            H  Cl    OCH.sub.3                                                                          CH 124-128                                   H      CO.sub.2 CH.sub.2 -cyclopropyl                                                            H  CH.sub.3                                                                            CH.sub.3                                                                           CH 134-138                                   H      CO.sub.2 CH.sub.2 -cyclopropyl                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          N  154-161                                   __________________________________________________________________________

                                      TABLE II                                    __________________________________________________________________________    General Formula 2                                                             R.sub.1                                                                            R.sub.3     R  X     Y    Z  m.p. (°C.)                           __________________________________________________________________________    H    SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.3  H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SOCH.sub.3  H  Cl    OCH.sub.3                                                                          CH                                             H    SOCH.sub.3  H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SOCH.sub.3  H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SOCH.sub.3  CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SOCH.sub.2 CH.sub.3                                                                       H  Cl    OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.3                                                                       H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SOCH.sub. 2 CH.sub.3                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SOCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  Cl    OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  Cl    OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SOCH.sub.2 CH.sub.2 CH.sub. 2 CH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SOCH(CH.sub.3).sub.2                                                                      H  Cl    OCH.sub.3                                                                          CH                                             H    SOCH(CH.sub.3).sub.2                                                                      H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SOCH(CH.sub.3).sub.2                                                                      CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    S-cyclopropyl                                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    S-cyclopropyl                                                                             H  Cl    OCH.sub.3                                                                          CH                                             H    S-cyclopropyl                                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    S-cyclopropyl                                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    S-cyclopropyl                                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    S-cyclopropyl                                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO-cyclopropyl                                                                            H  Cl    OCH.sub.3                                                                          CH                                             H    SO-cyclopropyl                                                                            H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO-cyclopropyl                                                                            H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO-cyclopropyl                                                                            CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 -cyclopropyl                                                                     H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 -cyclopropyl                                                                     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 -cyclopropyl                                                                     CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub. 3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    OSO.sub.2 CH.sub.3                                                                        H  Cl    OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.3                                                                        H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    OSO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  Cl    OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    OSO.sub.2 CF.sub.3                                                                        H  Cl    OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CF.sub.3                                                                        H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    OSO.sub.2 CF.sub. 3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    OSO.sub.2 CF.sub.3                                                                        CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl OSO.sub.2 CF.sub.3                                                                        H  OCO.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    OSO.sub.2 CCl.sub.3                                                                       H  Cl    OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CCl.sub.3                                                                       H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    OSO.sub.2 CCl.sub.3                                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  Cl    OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl OSO.sub. 2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCO.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 OCH.sub.2 CF.sub.3                                                               CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 OCH.sub.2 CF.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    P(O)(OCH.sub.3).sub.2                                                                     H  Cl    OCH.sub.3                                                                          CH                                             H    P(O)(OCH.sub.3).sub.2                                                                     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    P(O)(OCH.sub.3).sub.2                                                                     CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl P(O)(OCH.sub.3).sub.2                                                                     H  OCO.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CN          H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    CN          H  Cl    OCH.sub.3                                                                          CH                                             H    CN          H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CN          H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    CN          H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    CN          CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CH.sub.2 F  H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    CH.sub.2 F  H  Cl    OCH.sub.3                                                                          CH                                             H    CH.sub.2 F  H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CH.sub.2 F  H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    CH.sub.2 F  H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    CH.sub.2 F  CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CH.sub.2 F  H  OCO.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CH.sub.2 H  H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    CF.sub.2 H  H  Cl    OCH.sub.3                                                                          CH                                             H    CF.sub.2 H  H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CF.sub.2 H  H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    CF.sub.2 H  H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    CF.sub.2 H  CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CF.sub. 2 H H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.3                                                                       H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.3                                                                       H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 NHCH.sub.3                                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub. 3                                                                          CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           OCH.sub. 3                                                                         CH                                             H    SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 NHCH(CH.sub.3).sub.2                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  CH.sub.3                                                                            OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 NHCH(CH.sub.3).sub.2                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NH-cyclopropyl                                                                   H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NH-cyclopropyl                                                                   H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 NH-cyclopropyl                                                                   H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 NH-cyclopropyl                                                                   H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 NH-cyclopropyl                                                                   H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 NH-cyclopropyl                                                                   H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 NH-cyclopropyl                                                                   H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 NH-cyclopropyl                                                                   CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         SO.sub.2 NH-cyclopropyl                                                                   H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SO.sub.2 NH-cyclopropyl                                                                   H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 NH-cyclopropyl                                                                   H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 NH-cyclopropyl                                                                   H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 NH-cyclopropyl                                                                   H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 NH-cyclopropyl                                                                   H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub. 3                                                                          CH.sub.3                                                                           N                                              H    SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 NHCH.sub.2 CH═CH.sub.2                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 NHCH.sub.2 CF.sub.3                                                              CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 NHCH.sub.2 CF.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.2 CN                                                                    H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CN                                                                    H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 NHCH.sub.2 CN                                                                    CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 NHCH.sub.2 CN                                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 N(CH.sub.2 CH═CH.sub.2).sub.2                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 -pyrrolidino                                                                     H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 -pyrrolidino                                                                     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 -pyrrolidino                                                                     CH.sub.3                                                                         OCH.sub.3                                                                           CH   N                                              4-CH.sub.3                                                                         SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 -pyrrolidino                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NH.sub.2                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NH.sub.2                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 NH.sub.2                                                                         H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 NH.sub.2                                                                         H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 NH.sub.2                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 NH.sub.2                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 NH.sub.2                                                                         H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 NH.sub.2                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         SO.sub.2 NH.sub.2                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl SO.sub.2 NH.sub.2                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 NH.sub.2                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 NH.sub. 2                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 NH.sub.2                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 NH.sub.2                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  Cl    OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub. 3                                                                         CH                                             6-F  CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCO.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  Cl    OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  Cl    OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub. 3                                                                          OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCO.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CF.sub.3                                                                H  Cl    OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CF.sub.3                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    CO.sub.2 CH.sub.2 CF.sub.3                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              4-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             4-Cl CO.sub.2 CH.sub.2 CF.sub. 3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             __________________________________________________________________________

                                      TABLE III                                   __________________________________________________________________________    General Formula 3                                                             R.sub.f                                                                            R.sub.4     R  X     Y    Z  m.p. (°C.)                           __________________________________________________________________________    H    SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.3  H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SOCH.sub.3  H  Cl    OCH.sub.3                                                                          CH                                             H    SOCH.sub.3  H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SOCH.sub.3  H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SOCH.sub.3  CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SOCH.sub.2 CH.sub.3                                                                       H  Cl    OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.3                                                                       H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SOCH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SOCH.sub.2 CH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  Cl    OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  SOCH.sub. 2 CH.sub.2 CH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  Cl    OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub. 3                                                                          OCH.sub.3                                                                          CH                                              -6-CH.sub.3                                                                       SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SOCH(CH.sub.3).sub.2                                                                      H  Cl    OCH.sub.3                                                                          CH                                             H    SOCH(CH.sub.3).sub.2                                                                      H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SOCH(CH.sub.3).sub.2                                                                      CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    S-cyclopropyl                                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    S-cyclopropyl                                                                             H  Cl    OCH.sub.3                                                                          CH                                             H    S-cyclopropyl                                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    S-cyclopropyl                                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    S-cyclopropyl                                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    S-cyclopropyl                                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO-cyclopropyl                                                                            H  Cl    OCH.sub.3                                                                          CH                                             H    SO-cyclopropyl                                                                            H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO-cyclopropyl                                                                            H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO-cyclopropyl                                                                            CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 -cyclopropyl                                                                     H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 -cyclopropyl                                                                     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 -cyclopropyl                                                                     CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub. 2 CH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    OSO.sub.2 CH.sub.3                                                                        H  Cl    OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.3                                                                        H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    OSO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  Cl    OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    OSO.sub.2 CH.sub. 2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  Cl    OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl OSO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    OSO.sub.2 CF.sub.3                                                                        H  Cl    OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CF.sub.3                                                                        H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    OSO.sub.2 CF.sub.3                                                                        CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    OSO.sub.2 CCl.sub.3                                                                       H  Cl    OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CCl.sub.3                                                                       H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    OSO.sub.2 CCl.sub.3                                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub. 3                                                                          OCH.sub.3                                                                          CH                                             2-F  OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl OSO.sub.2 CCl.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    N.sub.3     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    N.sub.3     H  Cl    OCH.sub.3                                                                          CH                                             H    N.sub.3     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    N.sub.3     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    N.sub.3     H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    N.sub.3     CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub. 3                                                                         CH                                             H    P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    P(O)(OCH.sub.3).sub.2                                                                     H  Cl    OCH.sub.3                                                                          CH                                             H    P(O)(OCH.sub.3).sub.2                                                                     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    P(O)(OCH.sub.3).sub.2                                                                     CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl P(O)(OCH.sub.3).sub.2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CN          H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    CN          H  Cl    OCH.sub.3                                                                          CH                                             H    CN          H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CN                                             H    CN          H  OCH.sub.3                                                                           CH.sub.3                                                                           CN                                             H    CN          H  OCH.sub. 2 CH.sub.3                                                                 NHCH.sub.3                                                                         CN                                             H    CN          CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           CN                                             2-Cl CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CH.sub.2 F  H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    CH.sub.2 F  H  Cl    OCH.sub.3                                                                          CH                                             H    CH.sub.2 F  H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CH.sub.2 F  H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    CH.sub.2 F  H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    CH.sub.2 F  CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CF.sub.2 H  H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    CF.sub.2 H  H  Cl    OCH.sub.3                                                                          CH                                             H    CF.sub.2 H  H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CF.sub.2 H  H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CF.sub.2 H  CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  CH.sub.3                                                                            CH.sub. 3                                                                          CH                                             H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.3                                                                       H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.3                                                                       H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub. 3                                                                          N                                              H    SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 NHCH.sub.3                                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                    H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  Cl    OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    CO.sub.2 CH.sub.2 CH.sub. 2 OH                                                            CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  Cl    OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  Cl    OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    CO.sub.2 CH.sub.2 CH.sub. 2 OSO.sub.2 CH.sub.3                                            H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CF.sub.3                                                                H  Cl    OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CF.sub.3                                                                H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CO.sub.2 CH.sub.2 CF.sub.3                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              2-Cl CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             2-F  CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CO.sub.2 CH.sub.2 CF.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             __________________________________________________________________________

                                      TABLE IV                                    __________________________________________________________________________    General Formula 4                                                             R.sub.f                                                                            R.sub.5     R  X     Y    Z  m.p. (°C.)                           __________________________________________________________________________    H    SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.3  H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SOCH.sub.3  H  Cl    OCH.sub.3                                                                          CH                                             H    SOCH.sub.3  H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SOCH.sub.3  H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SOCH.sub.3  H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SOCH.sub.3  CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SOCH.sub.3  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 CH.sub. 3                                                                        H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 CH.sub.3                                                                         H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 CH.sub.3                                                                         H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 CH.sub.3                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  Cl    OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 CH.sub.2 CH.sub.3                                                                H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 CH.sub.2 CH.sub.3                                                                H  CH.sub.3                                                                            CH.sub. 3                                                                          CH                                             H    SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 CH.sub.2 CH.sub.3                                                                CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 CH.sub.2 CH.sub.3                                                                H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  Cl    OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  CH.sub. 3                                                                           CH.sub.3                                                                           CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SOCH.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SOCH.sub.2 CH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub. 2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  CH.sub.3                                                                            OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  Cl    OCH.sub.3                                                                          CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  CH.sub.2 CH.sub.3                                                                   NHCH.sub.3                                                                         N                                              H    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SOCH(CH.sub.3).sub.2                                                                      H  Cl    OCH.sub.3                                                                          CH                                             H    SOCH(CH.sub.3).sub.2                                                                      H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SOCH(CH.sub.3).sub.2                                                                      CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SOCH(CH.sub.3).sub. 2                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SOCH(CH.sub.3).sub.2                                                                      H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 CH(CH.sub.3).sub.2                                                               H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 CH(CH.sub.3).sub.2                                                               H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 CH(CH.sub.3).sub.2                                                               CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 CH(CH.sub.3).sub.2                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    S-cyclopropyl                                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    S-cyclopropyl                                                                             H  Cl    OCH.sub.3                                                                          CH                                             H    S-cyclopropyl                                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    S-cyclopropyl                                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    S-cyclopropyl                                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    S-cyclopropyl                                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl S-cyclopropyl                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO-cyclopropyl                                                                            H  Cl    OCH.sub.3                                                                          CH                                             H    SO-cyclopropyl                                                                            H  CH    CH.sub.3                                                                           CH                                             H    SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO-cyclopropyl                                                                            H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO-cyclopropyl                                                                            CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO-cyclopropyl                                                                            H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 -cyclopropyl                                                                     H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 -cyclopropyl                                                                     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 -cyclopropyl                                                                     CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 -cylcopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 -cyclopropyl                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub. 2 CH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    OSO.sub.2 CH.sub.3                                                                        H  Cl    OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.3                                                                        H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    OSO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl OSO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    OSO.sub.2 CF.sub.3                                                                        H  Cl    OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CF.sub.3                                                                        H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    OSO.sub.2 CF.sub.3                                                                        CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl OSO.sub.2 CF.sub.3                                                                        H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  Cl    OCH.sub.3                                                                          CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    OSO.sub. 2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl OSO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    N.sub.3     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    N.sub.3     H  Cl    OCH.sub.3                                                                          CH                                             H    N.sub.3     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    N.sub.3     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    N.sub.3     H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    N.sub.3     CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        N.sub.3     H  OCH.sub. 3                                                                          OCH.sub.3                                                                          CH                                             6-F  N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl N.sub.3     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CN          H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    CN          H  Cl    OCH.sub.3                                                                          CH                                             H    CN          H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CN          H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    CN          H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    CN          CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         CN          H  OCH.sub.3                                                                           OCH  CH                                             5-OCH.sub.3                                                                        CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CN          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CH.sub.2 F  H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    CH.sub.2 F  H  Cl    OCH.sub.3                                                                          CH                                             H    CH.sub.2 F  H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CH.sub.2 F  H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    CH.sub. 2 F H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    CH.sub.2 F  CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CH.sub.2 F  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CF.sub.2 H  H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    CF.sub.2 H  H  Cl    OCH.sub.3                                                                          CH                                             H    CF.sub.2 H  H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CF.sub.2 H  H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    CF.sub.2 H  H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    CF.sub.2 H  CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CF.sub.2 H  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub. 3                                                                          OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 N(OCH.sub.3)CH.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.3                                                                       H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.3                                                                       H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 NHCH.sub.3                                                                       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 NHCH.sub.3                                                                       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  Cl    OCH.sub.3                                                                          CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    SO.sub.2 NHCH.sub.2 CH.sub.3                                                              CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl SO.sub.2 NHCH.sub.2 CH.sub.3                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  Cl    OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           CCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CO.sub.2 CH.sub.2 CH.sub.2 OH                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  Cl    OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CO.sub.2 CH.sub.2 CH.sub.2 CN                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           CH.sub. 3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  Cl    OCH.sub.3                                                                          CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                             H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                              H    CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                              5-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             5-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-F  CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             6-Cl CO.sub.2 CH.sub.2 CH.sub.2 OSO.sub.2 CH.sub.3                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                             __________________________________________________________________________

                                      TABLE V                                     __________________________________________________________________________    General Formula 5                                                             R.sub.f                                                                            R.sub.6  R  X     Y    Z  m.p. (°C.)                              __________________________________________________________________________    H    SCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    SCH.sub.3                                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    SCH.sub.3                                                                              H  Cl    OCH.sub.3                                                                          CH                                                H    SCH.sub.3                                                                              H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    SCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                                 H    SCH.sub.3                                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 H    SCH.sub.3                                                                              H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    SCH.sub.3                                                                              CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         SCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-OCH.sub.3                                                                        SCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         SCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-OCH.sub.3                                                                        SCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  SCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-Cl SCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    SOCH.sub.3                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    SOCH.sub.3                                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    SOCH.sub.3                                                                             H  Cl    OCH.sub.3                                                                          CH                                                H    SOCH.sub.3                                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    SOCH.sub.3                                                                             H  OCH.sub. 3                                                                          OCH.sub.3                                                                          N                                                 H    SOCH.sub.3                                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 H    SOCH.sub.3                                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    SOCH.sub.3                                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         SOCH.sub.3                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-OCH.sub.3                                                                        SOCH.sub.3                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         SOCH.sub.3                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-OCH.sub.3                                                                        SOCH.sub.3                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  SOCH.sub.3                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-Cl SOCH.sub.3                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    SO-cyclopropyl                                                                         H  Cl    OCH.sub.3                                                                          CH                                                H    SO-cyclopropyl                                                                         H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                                 H    SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 H    SO-cyclopropyl                                                                         H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    SO-cyclopropyl                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-OCH.sub.3                                                                        SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-OCH.sub.3                                                                        SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           OCH.sub. 3                                                                         CH                                                6-Cl SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    SO.sub.2 -cyclopropyl                                                                  H  Cl    OCH.sub.3                                                                          CH                                                H    SO.sub.2 -cyclopropyl                                                                  H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                                 H    SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 H    SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    SO.sub.2 -cyclopropyl                                                                  CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-OCH.sub.3                                                                        SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-OCH.sub.3                                                                        SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-Cl SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    OSO.sub.2 CH.sub.3                                                                     H  Cl    OCH.sub.3                                                                          CH                                                H    OSO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                                 H    OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 H    OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    OSO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-OCH.sub.3                                                                        OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-OCH.sub.3                                                                        OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-Cl OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    CN       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    CN       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    CN       H  Cl    OCH.sub.3                                                                          CH                                                H    CN       H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    CN       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                                 H    CN       H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 H    CN       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    CN       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         CN       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-OCH.sub.3                                                                        CN       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         CN       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-OCH.sub.3                                                                        CN       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  CN       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-Cl CN       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    CH.sub.2 F                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    CH.sub.2 F                                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    CH.sub.2 F                                                                             H  Cl    OCH.sub.3                                                                          CH                                                H    CH.sub.2 F                                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    CH.sub.2 F                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                                 H    CH.sub.2 F                                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 H    CH.sub.2 F                                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    CH.sub.2 F                                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         CH.sub.2 F                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-OCH.sub.3                                                                        CH.sub.2 F                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         CH.sub.2 F                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-OCH.sub.3                                                                        CH.sub.2 F                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  CH.sub.2 F                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-Cl CH.sub.2 F                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  Cl    OCH.sub.3                                                                          CH                                                H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                                 H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-OCH.sub.3                                                                        SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-OCH.sub.3                                                                        SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-Cl SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  Cl    OCH.sub.3                                                                          CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                                 H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-Cl CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  Cl    OCH.sub.3                                                                          CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                                 H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-Cl CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    CO.sub.2 CH.sub.2 CF.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    CO.sub.2 CH.sub.2 CF.sub.3                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    CO.sub.2 CH.sub.2 CF.sub.3                                                             H  Cl    OCH.sub.3                                                                          CH                                                H    CO.sub.2 CH.sub.2 CF.sub.3                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    CO.sub.2 CH.sub.2 CF.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                                 H    CO.sub.2 CH.sub.2 CF.sub.3                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 H    CO.sub.2 CH.sub.2 CF.sub.3                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    CO.sub.2 CH.sub.2 CF.sub.3                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CF.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CF.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CF.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CF.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  CO.sub.2 CH.sub.2 CF.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-Cl CO.sub.2 CH.sub.2 CF.sub.3                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                __________________________________________________________________________

                                      TABLE VI                                    __________________________________________________________________________    General Formula 6                                                             R.sub.f                                                                            R.sub.6  R  X     Y    Z  m.p. (°C.)                              __________________________________________________________________________    H    SCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    SCH.sub.3                                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    SCH.sub.3                                                                              H  Cl    OCH.sub.3                                                                          CH                                                H    SCH.sub.3                                                                              H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    SCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                                 H    SCH.sub.3                                                                              H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 H    SCH.sub.3                                                                              H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    SCH.sub.3                                                                              CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         SCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-Cl SCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         SCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-OCH.sub.3                                                                        SCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  SCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-Cl SCH.sub.3                                                                              H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    SOCH.sub.3                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    SOCH.sub.3                                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    SOCH.sub.3                                                                             H  Cl    OCH.sub.3                                                                          CH                                                H    SOCH.sub.3                                                                             H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    SOCH.sub.3                                                                             H  OCH.sub.3                                                                           OCH.sub. 3                                                                         N                                                 H    SOCH.sub.3                                                                             H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 H    SOCH.sub.3                                                                             H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    SOCH.sub.3                                                                             CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         SOCH.sub.3                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-Cl SOCH.sub.3                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         SOCH.sub.3                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-OCH.sub.3                                                                        SOCH.sub.3                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  SOCH.sub.3                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-Cl SOCH.sub.3                                                                             H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    SO-cyclopropyl                                                                         H  Cl    OCH.sub.3                                                                          CH                                                H    SO-cyclopropyl                                                                         H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                                 H    SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 H    SO-cyclopropyl                                                                         H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    SO-cyclopropyl                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-Cl SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-OCH.sub.3                                                                        SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-Cl SO-cyclopropyl                                                                         H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    SO.sub.2 -cyclopropyl                                                                  H  Cl    OCH.sub.3                                                                          CH                                                H    SO.sub.2 -cyclopropyl                                                                  H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                                 H    SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 H    SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    SO.sub.2 -cyclopropyl                                                                  CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-Cl SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-OCH.sub.3                                                                        SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-Cl SO.sub.2 -cyclopropyl                                                                  H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    OSO.sub.2 CH.sub.3                                                                     H  Cl    OCH.sub.3                                                                          CH                                                H    OSO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                                 H    OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 H    OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    OSO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-Cl OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-OCH.sub.3                                                                        OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-Cl OSO.sub.2 CH.sub.3                                                                     H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    CN       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    CN       H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    CN       H  Cl    OCH.sub.3                                                                          CH                                                H    CN       H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    CN       H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                                 H    CN       H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 H    CN       H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    CN       CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         CN       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-Cl CN       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         CN       H  OCH.sub.3                                                                           OCH.sub. 3                                                                         CH                                                6-OCH.sub.3                                                                        CN       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  CN       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-Cl CN       H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  Cl    OCH.sub.3                                                                          CH                                                H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                                 H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-Cl SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-OCH.sub.3                                                                        SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-Cl SO.sub.2 N(OCH.sub.3)CH.sub.3                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  Cl    OCH.sub.3                                                                          CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                                 H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-Cl CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-Cl CO.sub.2 CH.sub.2 CH.sub.2 OH                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.3                                                                           CH.sub.3                                                                           CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  Cl    OCH.sub.3                                                                          CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  CH.sub.3                                                                            CH.sub.3                                                                           CH                                                H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          N                                                 H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  CH.sub.3                                                                            CH.sub.3                                                                           N                                                 H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                                 H    CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                           N                                                 4-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                4-Cl CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-CH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-OCH.sub.3                                                                        CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                6-F  CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  CH.sub.3                                                                            OCH.sub. 3                                                                         CH                                                6-Cl CO.sub.2 CH.sub.2 CH.sub.2 CN                                                          H  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                                __________________________________________________________________________

                                      TABLE VII                                   __________________________________________________________________________    General Formula 7                                                             R.sub.1                                                                             R.sub.2    A  X      Y      m.p. (°C.)                           __________________________________________________________________________    H     SOCH.sub.3 A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     SOCH.sub.3 A-3                                                                              X.sub.1 = CH.sub.3                                        H     SOCH.sub.3 A-3                                                                              x.sub.1 = OCH                                             H     SOCH.sub.3 A-4                                                                              X.sub.3 = OCH.sub.3                                       H     SO.sub.2 CH.sub.3                                                                        A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     SO.sub.2 CH.sub.3                                                                        A-3                                                                              X.sub.1 = CH.sub.3                                        H     SO.sub.2 CH.sub.3                                                                        A-3                                                                              X.sub.1 = OCH.sub.3                                       H     SO.sub.2 CH.sub.3                                                                        A-4                                                                              X.sub.3 = OCH.sub.3                                       H     SOCH.sub.2 CH.sub.3                                                                      A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     SOCH CH3   A-3                                                                              X.sub.1 = CH.sub.3                                        H     SOCH.sub.2 CH.sub.3                                                                      A-3                                                                              X.sub.1 = OCH.sub.3                                       H     SOCH.sub.2 CH.sub.3                                                                      A-4                                                                              X.sub.3 = OCH.sub.3                                       H     SO.sub.2 CH.sub.2 CH.sub.3                                                               A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     SO.sub.2 CH.sub.2 CH.sub.3                                                               A-3                                                                              X.sub.1 = CH.sub.3                                        H     SO.sub.2 CH.sub.2 CH.sub.3                                                               A-3                                                                              X.sub.1 = OCH.sub.3                                       H     SO.sub.2 CH.sub.2 CH.sub.3                                                               A-4                                                                              X.sub.3 = OCH.sub.3                                       H     SOCH.sub.2 CH.sub.2 CH.sub.3                                                             A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     SOCH.sub.2 CH.sub.2 CH.sub.3                                                             A-3                                                                              X.sub.1 = CH.sub.3                                        H     SOCH.sub.2 CH.sub.2 CH.sub.3                                                             A-3                                                                              X.sub.1 = OCH.sub.3                                       H     SOCH.sub.2 CH.sub.2 CH.sub.3                                                             A-4                                                                              X.sub.3 = OCH.sub.3                                       H     SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      A-3                                                                              X.sub.1 = CH.sub.3                                        H     SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      A-3                                                                              X.sub.1 = OCH.sub.3                                       H     SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      A-4                                                                              X.sub.3 = OCH.sub. 3                                      H     SOCH(CH.sub.3 ).sub.2                                                                    A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     SOCH(CH.sub.3 ).sub.2                                                                    A-3                                                                              X.sub.1 = CH.sub.3                                        H     SOCH(CH.sub.3 ).sub.2                                                                    A-3                                                                              X.sub.1 = OCH.sub.3                                       H     SOCH(CH.sub.3 ).sub.2                                                                    A-4                                                                              X.sub.3 = OCH.sub.3                                       H     SO.sub.2 CH(CH.sub.3 ).sub.2                                                             A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     SO.sub.2 CH(CH.sub.3 ).sub.2                                                             A-3                                                                              X.sub.1 = CH.sub.3                                        H     SO.sub.2 CH(CH.sub.3 ).sub.2                                                             A-3                                                                              X.sub.1 = OCH.sub.3                                       H     SO.sub.2 CH(CH.sub.3 ).sub.2                                                             A-4                                                                              X.sub.3 = OCH.sub.3                                       H     SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    A-3                                                                              X.sub.1 = CH.sub.3                                        H     SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    A-3                                                                              X.sub.1 = OCH.sub.3                                       H     SOCH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                    A-4                                                                              X.sub.3 = OCH.sub.3                                       H     SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                             A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                             A-3                                                                              X.sub.1 = CH.sub.3                                        H     SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                             A-3                                                                              X.sub.1 = OCH.sub.3                                       H     SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                             A-4                                                                              X.sub.1 = OCH.sub.3                                       H     S-cyclopropyl                                                                            A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     S-cyclopropyl                                                                            A-3                                                                              X.sub.1 = CH.sub.3                                        H     S-cyclopropyl                                                                            A-3                                                                              X.sub.1 = OCH.sub.3                                       H     S-cyclopropyl                                                                            A-4                                                                              X.sub.3 = OCH.sub.3                                       H     SO.sub.2 -cyclopropyl                                                                    A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     SO.sub.2 -cyclopropyl                                                                    A-3                                                                              X.sub.1 = CH.sub.3                                        H     SO.sub.2 -cyclopropyl                                                                    A-3                                                                              X.sub.1 = OCH.sub.3                                       H     SO.sub.2 -cyclopropyl                                                                    A-4                                                                              X.sub.3 = OCH.sub.3                                       H     OSO.sub.2 CH.sub.3                                                                       A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     OSO.sub.2 CH.sub.3                                                                       A-3                                                                              X.sub.1 = CH.sub.3                                        H     OSO.sub.2 CH.sub.3                                                                       A-3                                                                              X.sub.1 = OCH.sub.3                                       H     OSO.sub.2 CH.sub.3                                                                       A-4                                                                              X.sub.3 = OCH.sub.3                                       H     OSO.sub.2 CH.sub.3                                                                       A-7                                                                              X.sub.4 = OCH.sub.3                                                                  Y.sub.4 = OCH.sub.3                                H     OSO.sub.2 CH.sub.2 CH.sub.3                                                              A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     OSO.sub.2 CH.sub.2 CH.sub.3                                                              A-3                                                                              X.sub.1 = CH.sub.3                                        H     OSO.sub.2 CH.sub.2 CH.sub.3                                                              A-3                                                                              X.sub.1 = OCH.sub.3                                       H     OSO.sub.2 CH.sub.2 CH.sub.3                                                              A-4                                                                              X.sub.3 = OCH.sub.3                                       H     OSO.sub.2 CF.sub.3                                                                       A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     OSO.sub.2 CF.sub.3                                                                       A-3                                                                              X.sub.1 = CH.sub.3                                        H     OSO.sub.2 CF.sub.3                                                                       A-3                                                                              X.sub.1 = OCH.sub.3                                       H     OSO.sub.2 CF.sub.3                                                                       A-4                                                                              X.sub.3 = OCH.sub.3                                       H     OSO.sub.2 CCl.sub.3                                                                      A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     OSO.sub.2 CCl.sub.3                                                                      A-3                                                                              X.sub.1 = CH.sub.3                                        H     OSO.sub.2 CCl.sub.3                                                                      A-3                                                                              X.sub.1 = OCH.sub.3                                       H     OSO.sub.2 CCl.sub.3                                                                      A-4                                                                              X.sub.3 = OCH.sub.3                                       H     CN         A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     CN         A-3                                                                              X.sub.1 = CH.sub.3                                        H     CN         A-3                                                                              X.sub.1 = OCH.sub.3                                       H     CN         A-4                                                                              X.sub.3 = OCH.sub.3                                       H     CH.sub.2 F A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     CH.sub.2 F A-3                                                                              X.sub.1 = CH.sub.3                                        H     CH.sub.2 F A-3                                                                              X.sub.1 = OCH.sub.3                                       H     CH.sub.2 F A-4                                                                              X.sub.3 = OCH.sub.3                                       H     CF.sub.2 H A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     CF.sub.2 H A-3                                                                              X.sub.1 = CH.sub.3                                        H     CF.sub.2 H A-3                                                                              X.sub.1 = OCH.sub. 3                                      H     CF.sub.2 H A-4                                                                              X.sub.3 = OCH.sub.3                                       H     SO.sub.2 NHCH.sub.3                                                                      A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     SO.sub.2 NHCH.sub.3                                                                      A-3                                                                              X.sub.1 = CH.sub.3                                        H     SO.sub.2 NHCH.sub.3                                                                      A-3                                                                              X.sub.1 = OCH.sub.3                                       H     SO.sub.2 NHCH.sub.3                                                                      A-4                                                                              X.sub.3 = OCH.sub.3                                       H     SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                   A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                   A-3                                                                              X.sub.1 = CH.sub.3                                        H     SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                   A-3                                                                              X.sub.1 = OCH.sub.3                                       H     SO.sub.2 NHCH.sub.2 CH.sub.2 OCH.sub.3                                                   A-4                                                                              X.sub.3 = OCH.sub.3                                       H     CO.sub.2 CH.sub.2 CH.sub.2 OH                                                            A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     CO.sub.2 CH.sub.2 CH.sub.2 OH                                                            A-3                                                                              X.sub.1 = CH.sub.3                                        H     CO.sub.2 CH.sub.2 CH.sub.2 OH                                                            A-3                                                                              X.sub.1 =  OCH.sub.3                                      H     CO.sub.2 CH.sub.2 CH.sub.2 OH                                                            A-4                                                                              X.sub.3 = OCH.sub.3                                       H     CO.sub.2 CH.sub.2 CH.sub.2 CN                                                            A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     CO.sub.2 CH.sub.2 CH.sub.2 CN                                                            A-3                                                                              X.sub.1 = CH.sub.3                                        H     CO.sub.2 CH.sub.2 CH.sub.2 CN                                                            A-3                                                                              X.sub.1 = OCH.sub.3                                       H     CO.sub.2 CH.sub.2 CH.sub.2 CN                                                            A-4                                                                              X.sub.3 = OCH.sub.3                                       H     CO.sub.2 CH.sub.2 CF.sub.2                                                               A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 H     CO.sub.2 CH.sub.2 CF.sub.2                                                               A-3                                                                              X.sub.1 = CH.sub.3                                        H     CO.sub.2 CH.sub.2 CF.sub.2                                                               A-3                                                                              X.sub.1 = OCH.sub.3                                       6-OCH.sub.3                                                                         SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 6-OCH.sub.3                                                                         SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-3                                                                              X.sub.1 = CH.sub.3                                        6-OCH.sub.3                                                                         SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-3                                                                              X.sub.1 = OCH.sub.3                                       6-OCH.sub. 3                                                                        SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-4                                                                              X.sub.3 = OCH.sub.3                                       6-SCH.sub.3                                                                         SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 6-SCH.sub.3                                                                         SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-3                                                                              X.sub.1 l = CH.sub.3                                      6-SCH.sub.3                                                                         SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-3                                                                              X.sub.1 = OCH.sub.3                                       6-SCH.sub.3                                                                         SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-4                                                                              X.sub.3 = OCH.sub.3                                       6-N(CH.sub.3 ).sub.2                                                                SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 6-N(CH.sub.3 ).sub.2                                                                SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-3                                                                              X.sub.1 = CH.sub.3                                        6-N(CH.sub.3 ).sub.2                                                                SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-3                                                                              X.sub.1 = OCH.sub.3                                       6-N(CH.sub.3 ).sub.2                                                                SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-4                                                                              X.sub.3 = OCH.sub.3                                       6-NHCH.sub.3                                                                        SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 =  CH.sub.2                                6-NHCH.sub.3                                                                        SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-3                                                                              X.sub.1 = CH.sub.3                                        6-NHCH.sub.3                                                                        SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-3                                                                              X.sub.1 = OCH.sub.3                                       6-NHCH.sub.3                                                                        SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-4                                                                              X.sub.3 = OCH.sub.3                                       6-OCH.sub.3                                                                         CO.sub.2 CH.sub.3                                                                        A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 6-OCH.sub.3                                                                         CO.sub.2 CH.sub.3                                                                        A-3                                                                              X.sub.1 = CH.sub.3                                        6-OCH.sub.3                                                                         CO.sub.2 CH.sub.3                                                                        A-3                                                                              X.sub.1 = OCH.sub.3                                       6-OCH.sub.3                                                                         CO.sub.2 CH.sub.3                                                                        A-4                                                                              X.sub.3 = OCH.sub.3                                       6-SCH.sub.3                                                                         CO.sub.2 CH.sub.3                                                                        A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 6-SCH.sub.3                                                                         CO.sub.2 CH.sub.3                                                                        A-3                                                                              X.sub.1 = CH.sub.3                                        6-SCH.sub.3                                                                         CO.sub.2 CH.sub.3                                                                        A-3                                                                              X.sub.1 = OCH.sub.3                                       6-SCH.sub.3                                                                         CO.sub.2 CH.sub.3                                                                        A-4                                                                              X.sub.3 = OCH.sub.3                                       6-N(CH.sub.3 ).sub.2                                                                CO.sub.2 CH.sub.3                                                                        A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 =  CH.sub.2                                6-N(CH.sub.3 ).sub.2                                                                CO.sub.2 CH.sub.3                                                                        A-3                                                                              X.sub.1 = CH.sub.3                                        6-N(CH.sub.3 ).sub.2                                                                CO.sub.2 CH.sub.3                                                                        A-3                                                                              X.sub.1 = OCH.sub.3                                       6-N(CH.sub.3 ).sub.2                                                                CO.sub.2 CH.sub.3                                                                        A-4                                                                              X.sub.3 = OCH.sub.3                                       6-NHCH.sub.3                                                                        SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 6-NHCH.sub.3                                                                        SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-3                                                                              X.sub.1 = CH.sub.3                                        6-NHCH.sub.3                                                                        SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-3                                                                              X.sub.1 = OCH.sub.3                                       6-OCH.sub.3                                                                         SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-4                                                                              X.sub.3 = OCH.sub.3                                       6-OCH.sub.3                                                                         SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 6-OCH.sub.3                                                                         SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-3                                                                              X.sub.1 = CH.sub.3                                        6-OCH.sub.3                                                                         SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-3                                                                              X.sub.1 = OCH.sub.3                                       6-OCH.sub.3                                                                         SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-4                                                                              X.sub.3  = OCH.sub.3                                      6-SCH.sub.3                                                                         SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 6-SCH.sub.3                                                                         SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-3                                                                              X.sub.1 = CH.sub.3                                        6-SCH.sub.3                                                                         SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-3                                                                              X.sub.1 = OCH.sub.3                                       6-SCH.sub.3                                                                         SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-4                                                                              X.sub.3 = OCH.sub.3                                       6-N(CH.sub.3 ).sub.2                                                                SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 6-N(CH.sub.3 ).sub.2                                                                SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-3                                                                              X.sub.1 = CH.sub.3                                        6-N(CH.sub.3 ).sub.2                                                                SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-3                                                                              X.sub.1 = OCH.sub.3                                       6-N(CH.sub.3 ).sub.2                                                                SO.sub.2 N(CH.sub.3 ).sub.2                                                              A-4                                                                              X.sub.3 = OCH.sub.3                                       6-NHCH.sub.3                                                                        CO.sub.2 CH.sub.3                                                                        A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 6-NHCH.sub.3                                                                        CO.sub.2 CH.sub.3                                                                        A-3                                                                              X.sub.1 = CH.sub.3                                        6-NHCH.sub.3                                                                        CO.sub.2 CH.sub.3                                                                        A-3                                                                              X.sub.1 = OCH.sub.3                                       6-NHCH.sub.3                                                                        CO.sub.2 CH.sub.3                                                                        A-4                                                                              X.sub.3 = OCH.sub.3                                       6-OCH.sub.3                                                                         SO.sub.2 NHOCH.sub.3                                                                     A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 6-OCH.sub.3                                                                         SO.sub.2 NHOCH.sub.3                                                                     A-3                                                                              X.sub.1 = CH.sub.3                                        6-OCH.sub.3                                                                         SO.sub.2 NHOCH.sub.3                                                                     A-3                                                                              X.sub.1 = OCH.sub.3                                       6-OCH.sub.3                                                                         SO.sub.2 NHOCH.sub.3                                                                     A-4                                                                              X.sub.3 = OCH.sub.3                                       6-SCH.sub.3                                                                         SO.sub.2 NHOCH.sub.3                                                                     A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 6-SCH.sub.3                                                                         SO.sub.2 NHOCH.sub.3                                                                     A-3                                                                              X.sub.1 = CH.sub.3                                        6-SCH.sub.3                                                                         SO.sub.2 NHOCH.sub.3                                                                     A-3                                                                              X.sub.1 = OCH.sub.3                                       6-SCH.sub.3                                                                         SO.sub.2 NHOCH.sub.3                                                                     A-4                                                                              X.sub.3 = OCH.sub.3                                       6-N(CH.sub.3 ).sub.2                                                                SO.sub.2 NHOCH.sub.3                                                                     A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 6-N(CH.sub.3 ).sub.2                                                                SO.sub.2 NHOCH.sub.3                                                                     A-3                                                                              X.sub.1 = CH.sub.3                                        6-N(CH.sub.3 ).sub.2                                                                SO.sub.2 NHOCH.sub.3                                                                     A-3                                                                              X.sub.1 = OCH.sub.3                                       6-N(CH.sub.3 ).sub.2                                                                SO.sub.2 NHOCH.sub.3                                                                     A-4                                                                              X.sub.3 = OCH.sub.3                                       6-NHCH.sub.3                                                                        SO.sub.2 NHOCH.sub.3                                                                     A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 6-NHCH.sub.3                                                                        SO.sub.2 NHOCH.sub.3                                                                     A-3                                                                              X.sub.1 = CH.sub.3                                        6-NHCH.sub.3                                                                        SO.sub.2 NHOCH.sub.3                                                                     A-3                                                                              X.sub.1 = OCH.sub.3                                       6-NHCH.sub.3                                                                        SO.sub.2 NHOCH.sub.3                                                                     A-4                                                                              X.sub.3 = OCH.sub.3                                       6-OCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                               A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 6-OCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                               A-3                                                                              X.sub.1 = CH.sub.3                                        6-OCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                               A-3                                                                              X.sub.1 = OCH.sub.3                                       6-OCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                               A-4                                                                              X.sub.3 = OCH.sub.3                                       6-OCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                               A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 6-OCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                               A-3                                                                              X.sub.1 = CH.sub.3                                        6-OCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                               A-3                                                                              X.sub.1 = OCH.sub.3                                       6-OCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                               A-4                                                                              X.sub.3 = OCH.sub.3                                       6-OCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                               A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 6-OCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                               A-3                                                                              X.sub.1 = CH.sub.3                                        6-OCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                               A-3                                                                              X.sub.1 = OCH.sub.3                                       6-OCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                               A-4                                                                              X.sub.3 = OCH.sub.3                                       6-OCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                               A-2                                                                              X.sub.1 = CH.sub.3                                                                   Y.sub.1 = CH.sub.2                                 6-OCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                               A-3                                                                              X.sub.1 = CH.sub.3                                        6-OCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                               A-3                                                                              X.sub.1 = OCH.sub.3                                       6-OCH.sub.3                                                                         CO.sub.2 CH.sub.2 CH.sub.3                                                               A-4                                                                              X.sub.3 = OCH.sub.3                                       __________________________________________________________________________

                  TABLE VIII                                                      ______________________________________                                        General Formula 8                                                                                                       m.p.                                R.sub.1                                                                           R.sub.3      A      X        Y        (°C.)                        ______________________________________                                        H   SOCH.sub.3   A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SOCH.sub.3   A-3    X.sub.1 = CH.sub.3                                    H   SOCH.sub.3   A-3    X.sub.1 = OCH.sub.3                                   H   SOCH.sub.3   A-4    X.sub.3 = OCH.sub.3                                   H   SOCH.sub.2 CH.sub.3                                                                        A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SOCH.sub.2 CH.sub.3                                                                        A-3    X.sub.1 = CH.sub.3                                    H   SOCH.sub.2 CH.sub.3                                                                        A-3    X.sub.1 = OCH.sub.3                                   H   SOCH.sub.2 CH.sub.3                                                                        A-4    X.sub.3 = OCH.sub.3                                   H   SOCH.sub.2 CH.sub.2 CH.sub.3                                                               A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SOCH.sub.2 CH.sub.2 CH.sub.3                                                               A-3    X.sub.1 = CH.sub.3                                    H   SOCH.sub.2 CH.sub.2 CH.sub.3                                                               A-3    X.sub.1 = OCH.sub.3                                   H   SOCH.sub.2 CH.sub.2 CH.sub.3                                                               A-4    X.sub.3 = OCH.sub.3                                   H   S-cyclopropyl                                                                              A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   S-cyclopropyl                                                                              A-3    X.sub.1 = CH.sub.3                                    H   S-cyclopropyl                                                                              A-3    X.sub.1 = OCH.sub.3                                   H   S-cyclopropyl                                                                              A-4    X.sub.3 = OCH.sub.3                                   H   SO.sub.2 -cyclopropyl                                                                      A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SO.sub.2 -cyclopropyl                                                                      A-3    X.sub.1 = CH.sub.3                                    H   SO.sub.2 -cyclopropyl                                                                      A-3    X.sub.1 = OCH.sub.3                                   H   SO.sub.2 -cyclopropyl                                                                      A-4    X.sub.3 = OCH.sub.3                                   H   OSO.sub.2 CH.sub.3                                                                         A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   OSO.sub.2 CH.sub.3                                                                         A-3    X.sub.1 = CH.sub.3                                    H   OSO.sub.2 CH.sub.3                                                                         A-3    X.sub.1 = OCH.sub.3                                   H   OSO.sub.2 CH.sub.3                                                                         A-4    X.sub.3 = OCH.sub.3                                   H   OSO.sub.2 CH.sub.2 CH.sub.3                                                                A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   OSO.sub.2 CH.sub.2 CH.sub.3                                                                A-3    X.sub.1 = CH.sub.3                                    H   OSO.sub.2 CH.sub.2 CH.sub.3                                                                A-3    X.sub.1 = OCH.sub.3                                   H   OSO.sub.2 CH.sub.2 CH.sub.3                                                                A-4    X.sub.3 = OCH.sub.3                                   H   OSO.sub.2 CF.sub.3                                                                         A-2    x.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   OSO.sub.2 CF.sub.3                                                                         A-3    X.sub.1 = CH.sub.3                                    H   OSO.sub.2 CF.sub.3                                                                         A-3    X.sub.1 = OCH.sub.3                                   H   OSO.sub.2 CF.sub.3                                                                         A-4    X.sub.3 = OCH.sub.3                                   H   OSO.sub.2 CCl.sub.3                                                                        A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   OSO.sub.2 CCl.sub.3                                                                        A-3    X.sub.1 = CH.sub.3                                    H   OSO.sub.2 CCl.sub.3                                                                        A-3    X.sub.1 = OCH.sub.3                                   H   OSO.sub.2 CCl.sub.3                                                                        A-4    x.sub.3 = CH.sub.3                                                                     CH3                                          H   CH.sub.2 F   A-2    X.sub.1 = CH.sub.3                                    H   CH.sub.2 F   A-3    X.sub.1 = CH.sub.3                                    H   CH.sub.2 F   A-3    X.sub.1 = OCH.sub.3                                   H   CH.sub.2 F   A-4    X.sub.3 = OCH.sub.3                                   H   SO.sub.2 NHCH.sub. 3                                                                       A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SO.sub.2 NHCH.sub.3                                                                        A-3    X.sub.1 = CH.sub.3                                    H   SO.sub.2 NHCH.sub.3                                                                        A-3    X.sub.1 = OCH.sub.3                                   H   SO.sub.2 NHCH.sub.3                                                                        A-4    X.sub.3 = OCH.sub.3                                   H   CO.sub.2 CH.sub.2 CH.sub.2 OH                                                              A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   CO.sub.2 CH.sub.2 CH.sub.2 OH                                                              A-3    X.sub.1 = CH.sub.3                                    H   CO.sub.2 CH.sub.2 CH.sub.2 OH                                                              A-3    X.sub.1 = OCH.sub.3                                   H   CO.sub.2 CH.sub.2 CH.sub.2 OH                                                              A-4    X.sub.3 = OCH.sub.3                                   H   CO.sub.2 CH.sub.2 CH.sub.2 CN                                                              A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   CO.sub.2 CH.sub.2 CH.sub.2 CN                                                              A-3    X.sub.1 = CH.sub.3                                    H   CO.sub.2 CH.sub.2 CH.sub.2 CN                                                              A-3    X.sub.1 = OCH.sub.3                                   H   CO.sub.2 CH.sub.2 CF.sub.3                                                                 A-4    X.sub.3 = OCH.sub.3                                   H   CO.sub.2 CH.sub. 2 CF.sub.3                                                                A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   CO.sub.2 CH.sub.2 CF.sub.3                                                                 A-3    X.sub.1 = CH.sub.3                                    H   CO.sub.2 CH.sub.2 CF.sub.3                                                                 A-3    X.sub.1 = OCH.sub.3                                   H   CO.sub.2 CH.sub.2 CF.sub.3                                                                 A-4    X.sub.3 = OCH.sub.3                                   ______________________________________                                    

                  TABLE IX                                                        ______________________________________                                        General Formula 9                                                                                                       m.p.                                R.sub.f                                                                           R.sub.4      A      X        Y        (°C.)                        ______________________________________                                        H   SOCH.sub.3   A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SOCH.sub.3   A-3    X.sub.1 = CH.sub.3                                    H   SOCH.sub.3   A-3    X.sub.1 = OCH.sub.3                                   H   SOCH.sub.3   A-4    X.sub.3 = OCH.sub.3                                   H   SOCH.sub.2 CH.sub.3                                                                        A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SOCH.sub.2 CH.sub.3                                                                        A-3    X.sub.1 = CH.sub.3                                    H   SOCH.sub.2 CH.sub.3                                                                        A-3    X.sub.1 = OCH.sub.3                                   H   SOCH.sub.2 CH.sub.3                                                                        A-4    X.sub.3 = OCH.sub.3                                   H   SOCH.sub.2 CH.sub.2 CH.sub.3                                                               A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SOCH.sub.2 CH.sub.2 CH.sub.3                                                               A-3    X.sub.1 = CH.sub.3                                    H   SOCH.sub.2 CH.sub.2 CH.sub.3                                                               A-3    X.sub.1 = OCH.sub.3                                   H   SOCH.sub.2 CH.sub.2 CH.sub.3                                                               A-4    X.sub.3 = OCH.sub.3                                   H   S-cyclopropyl                                                                              A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   S-cyclopropyl                                                                              A-3    X.sub.1 = CH.sub.3                                    H   S-cyclopropyl                                                                              A-3    x.sub.1 = OCH.sub.3                                   H   S-cyclopropyl                                                                              A-4    X.sub.3 = OCH.sub.3                                   H   SO-cyclopropyl                                                                             A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SO-cyclopropyl                                                                             A-3    X.sub.1 = CH.sub.3                                    H   SO-cyclopropyl                                                                             A-3    X.sub.1 = OCH.sub.3                                   H   SO-cyclopropyl                                                                             A-4    X.sub.3 = OCH.sub.3                                   H   SO.sub.2 -cyclopropyl                                                                      A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SO.sub.2 -cyclopropyl                                                                      A-3    X.sub.1 = CH.sub.3                                    H   SO.sub.2 -cyclopropyl                                                                      A-3    X.sub.1 = OCH.sub.3                                   H   SO.sub.2 -cyclopropyl                                                                      A-4    X.sub.3 = OCH.sub.3                                   H   OSO.sub.2 CH.sub.3                                                                         A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   OSO.sub.2 CH.sub.3                                                                         A-3    X.sub.1 = CH.sub.3                                    H   OSO.sub.2 CH.sub.3                                                                         A-3    X.sub.1 = OCH.sub.3                                   H   OSO.sub.2 CH.sub.3                                                                         A-4    X.sub.3 = OCH.sub.3                                   H   OSO.sub.2 CH.sub.2 CH.sub.3                                                                A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   OSO.sub.2 CH.sub.2 CH.sub.3                                                                A-3    X.sub.1 = CH.sub.3                                    H   OSO.sub.2 CH.sub.2 CH.sub.3                                                                A-3    X.sub.1 = OCH.sub.3                                   H   OSO.sub.2 CH.sub.2 CH.sub.3                                                                A-4    X.sub.3 = OCH.sub.3                                   H   OSO.sub.2 CF.sub.3                                                                         A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   OSO.sub.2 CF.sub.3                                                                         A-3    X.sub.1 = CH.sub.3                                    H   OSO.sub.2 CF.sub.3                                                                         A-3    X.sub.1 = OCH.sub.3                                   H   OSO.sub.2 CF.sub.3                                                                         A-4    X.sub.3 = OCH.sub.3                                   H   CH.sub.2 F   A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   CH.sub.2 F   A-3    X.sub.1 = CH.sub.3                                    H   CH.sub.2 F   A-3    X.sub.1 = OCH.sub.3                                   H   CH.sub.2 F   A-4    X.sub.3 = OCH.sub.3                                   H   CN           A-2    X.sub.1 = CH.sub.3                                                                     Y.sub. 1 = CH.sub.2                          H   CN           A-3    X.sub.1 = CH.sub.3                                    H   CN           A-3    X.sub.1 = OCH.sub.3                                   H   CN           A-4    X.sub.3 = OCH.sub.3                                   H   SO.sub.2 N(OCH.sub.3 )CH.sub.3                                                             A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SO.sub.2 N(OCH.sub.3 )CH.sub.3                                                             A-3    X.sub.1 = CH.sub.3                                    H   SO.sub.2 N(OCH.sub.3 )CH.sub.3                                                             A-3    X.sub.1 = OCH.sub.3                                   H   SO.sub.2 N(OCH.sub.3 )CH.sub.3                                                             A-4    X.sub.3 = OCH.sub.3                                   H   SO.sub.2 NHCH.sub.3                                                                        A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SO.sub.2 NHCH.sub.3                                                                        A-3    X.sub.1 = CH.sub.3                                    H   SO.sub.2 NHCH.sub.3                                                                        A-3    X.sub.1 = OCH.sub.3                                   H   SO.sub.2 NHCH.sub.3                                                                        A-4    X.sub.3 = OCH.sub.3                                   H   CO.sub.2 CH.sub.2 CH.sub.2 OH                                                              A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   CO.sub.2 CH.sub.2 CH.sub.2 OH                                                              A-3    X.sub.1 = CH.sub.3                                    H   CO.sub.2 CH.sub.2 CH.sub.2 OH                                                              A-3    X.sub.1 = OCH.sub.3                                   H   CO.sub.2 CH.sub.2 CH.sub.2 OH                                                              A-4    X.sub.3 = OCH.sub.3                                   H   CO.sub.2 CH.sub.2 CH.sub.2 CN                                                              A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   CO.sub.2 CH.sub.2 CH.sub.2 CN                                                              A-3    X.sub.1 = CH.sub.3                                    H   CO.sub.2 CH.sub.2 CH.sub.2 CN                                                              A-3    X.sub.1 = OCH.sub.3                                   H   CO.sub.2 CH.sub.2 CH.sub.2 CN                                                              A-4    X.sub.3 = OCH.sub.3                                   H   CO.sub.2 CH.sub.2 CF.sub.3                                                                 A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   CO.sub.2 CH.sub.2 CF.sub.3                                                                 A-3    X.sub.1 = CH.sub.3                                    H   CO.sub.2 CH.sub.2 CF.sub.3                                                                 A-3    X.sub.1 = OCH.sub.3                                   H   CO.sub.2 CH.sub.2 CF.sub.3                                                                 A-4    X.sub.3 = OCH.sub.3                                   ______________________________________                                    

                  TABLE X                                                         ______________________________________                                        General Formula 10                                                                                                      m.p.                                R.sub.1                                                                           R.sub.3      A      X        Y        (°C.)                        ______________________________________                                        H   SOCH.sub.3   A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SOCH.sub.3   A-3    X.sub.1 = CH.sub.3                                    H   SOCH.sub.3   A-3    X.sub.1 = OCH.sub.3                                   H   SOCH.sub.3   A-4    X.sub.3 = OCH.sub.3                                   H   SOCH.sub.2 CH.sub.3                                                                        A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SOCH.sub.2 CH.sub.3                                                                        A-3    X.sub.1 = CH.sub.3                                    H   SOCH.sub.2 CH.sub.3                                                                        A-3    X.sub.1 = OCH.sub.3                                   H   SOCH.sub.2 CH.sub.3                                                                        A-4    X.sub.3 = OCH.sub.3                                   H   SOCH.sub.2 CH.sub.2 CH.sub.3                                                               A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SOCH.sub.2 CH.sub.2 CH.sub.3                                                               A-3    X.sub.1 = CH.sub.3                                    H   SOCH.sub.2 CH.sub.2 CH.sub.3                                                               A-3    X.sub.1 = OCH.sub.3                                   H   SOCH.sub.2 CH.sub.2 CH.sub.3                                                               A-4    X.sub.3 = OCH.sub.3                                   H   SO.sub.2 CH.sub.3                                                                          A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SO.sub.2 CH.sub.3                                                                          A-3    X.sub.1 = CH.sub.3                                    H   SO.sub.2 CH.sub.3                                                                          A-3    X.sub.1 = OCH.sub.3                                   H   SO.sub.2 CH.sub.3                                                                          A-4    X.sub.3 = OCH.sub.3                                   H   SO.sub.2 CH.sub.2 CH.sub.3                                                                 A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SO.sub.2 CH.sub.2 CH.sub.3                                                                 A-3    X.sub.1 = CH.sub.3                                    H   SO.sub.2 CH.sub.2 CH.sub.3                                                                 A-3    X.sub.1 = OCH.sub.3                                   H   SO.sub.2 CH.sub.2 CH.sub.3                                                                 A-4    X.sub.3 = OCH.sub.3                                   H   SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        A-3    X.sub.1 = CH.sub.3                                    H   SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                        A-3    X.sub.1 = OCH.sub.3                                   H   SO.sub.2 CH.sub. 2 CH.sub.2 CH.sub.3                                                       A-4    X.sub.3 = OCH.sub.3                                   H   S-cyclopropyl                                                                              A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   S-cyclopropyl                                                                              A-3    X.sub.1 = CH.sub.3                                    H   S-cyclopropyl                                                                              A-3    X.sub.1 = OCH.sub.3                                   H   S-cyclopropyl                                                                              A-4    X.sub.3 = OCH.sub.3                                   H   SO-cyclopropyl                                                                             A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SO-cyclopropyl                                                                             A-3    X.sub.1 = CH.sub.3                                    H   SO-cyclopropyl                                                                             A-3    X.sub.1 = OCH.sub.3                                   H   SO-cyclopropyl                                                                             A-4    X.sub.3 = OCH.sub.3                                   H   SO.sub.2 -cyclopropyl                                                                      A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SO.sub.2 -cyclopropyl                                                                      A-3    X.sub.1 = CH.sub.3                                    H   SO.sub.2 -cyclopropyl                                                                      A-3    X.sub.1 = OCH.sub.3                                   H   SO.sub.2 -cyclopropyl                                                                      A-4    X.sub.3 = OCH.sub.3                                   H   OSO.sub.2 CH.sub.3                                                                         A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   OSO.sub.2 CH.sub.3                                                                         A-3    X.sub.1 = CH.sub.3                                    H   OSO.sub.2 CH.sub.3                                                                         A-3    X.sub. 1 = OCH.sub.3                                  H   OSO.sub.2 CH.sub.3                                                                         A-4    X.sub.3 = OCH.sub.3                                   H   CH.sub.2 F   A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   CH.sub.2 F   A-3    X.sub.1 = CH.sub.3                                    H   CH.sub.2 F   A-3    X.sub.1 = OCH.sub.3                                   H   CH.sub.2 F   A-4    X.sub.3 = OCH.sub.3                                   H   CN           A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   CN           A-3    X.sub.1 = CH.sub.3                                    H   CN           A-3    X.sub.1 = OCH.sub.3                                   H   CN           A-4    X.sub.3 = OCH.sub.3                                   H   SO.sub.2 N(OCH.sub.3 )CH.sub.3                                                             A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SO.sub.2 N(OCH.sub.3 )CH.sub.3                                                             A-3    X.sub.1 = CH.sub.3                                    H   SO.sub.2 N(OCH.sub.3 )CH.sub.3                                                             A-3    X.sub.1 = OCH.sub.3                                   H   SO.sub.2 N(OCH.sub.3 )CH.sub.3                                                             A-4    X.sub.3 = OCH.sub.3                                   H   SO.sub.2 NHCH.sub.3                                                                        A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SO.sub.2 NHCH.sub.3                                                                        A-3    X.sub.1 = CH.sub.3                                    H   SO.sub.2 NHCH.sub.3                                                                        A-3    X.sub.1 = OCH.sub.3                                   H   SO.sub.2 NHCH.sub.3                                                                        A-4    X.sub.3 = OCH.sub.3                                   H   SO.sub.2 NHCH.sub.2 CH.sub.3                                                               A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   SO.sub.2 NHCH.sub.2 CH.sub.3                                                               A-3    X.sub.1 = CH.sub.3                                    H   SO.sub.2 NHCH.sub.2 CH.sub.3                                                               A-3    X.sub.1 = OCH.sub.3                                   H   SO.sub.2 NHCH.sub.2 CH.sub.3                                                               A-4    X.sub.3 = OCH.sub.3                                   H   CO.sub.2 CH.sub.2 CH.sub.2 OH                                                              A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   CO.sub.2 CH.sub.2 CH.sub.2 OH                                                              A-3    X.sub.1 = CH.sub.3                                    H   CO.sub.2 CH.sub.2 CH.sub.2 OH                                                              A-3    X.sub.1 = OCH.sub.3                                   H   CO.sub.2 CH.sub.2 CH.sub.2 OH                                                              A-4    X.sub.3 = OCH.sub.3                                   H   CO.sub.2 CH.sub.2 CH.sub.2 CN                                                              A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   CO.sub.2 CH.sub.2 CH.sub.2 CN                                                              A-3    X.sub.1 = CH.sub.3                                    H   CO.sub.2 CH.sub.2 CH.sub.2 CN                                                              A-3    X.sub.1 = OCH.sub.3                                   H   CO.sub.2 CH.sub.2 CH.sub.2 CN                                                              A-4    X.sub.3 = OCH.sub.3                                   H   CO.sub.2 CH.sub.2 CF.sub.3                                                                 A-2    X.sub.1 = CH.sub.3                                                                     Y.sub.1 = CH.sub.2                           H   CO.sub.2 CH.sub.2 CF.sub.3                                                                 A-3    X.sub.1 = CH.sub.3                                    H   CO.sub.2 CH.sub.2 CF.sub.3                                                                 A-3    X.sub.1 = OCH.sub.3                                   H   CO.sub.2 CH.sub.2 CF.sub.3                                                                 A-4    X.sub.3 = OCH.sub.3                                   ______________________________________                                    

Formulations

Useful formulations of the compounds of Formula I can be prepared inconventional ways. They include dusts, granules, pellets, solutions,suspensions, emulsions, wettable powders, emulsifiable concentrates andthe like. Many of these may be applied directly. Sprayable formulationscan be extended in suitable media and used at spray volumes of from afew liters to several hundred liters per hectare. High strengthcompositions are primarily used as intermediates for furtherformulation. The formulations, broadly, contain about 0.1% to 99% byweight of active ingredient(s) and at least one of (a) about 0.1% to 20%surfactant(s) and (b) about 1% to 99.9% solid or liquid inertdiluent(s). More specifically, they will contain these ingredients inthe following approximate proportions:

    ______________________________________                                                    Weight Percent*                                                               Active                                                                        Ingredient                                                                            Diluent(s)                                                                              Surfactant(s)                                   ______________________________________                                        Wettable Powders                                                                            20-90      0-74     1-10                                        Oil Suspensions,                                                                             3-50     40-95     0-15                                        Emulsions, Solutions,                                                         (including Emulsifiable                                                       Concentrates)                                                                 Aqueous Suspension                                                                          10-50     40-84     1-20                                        Dusts          1-25     70-99     0-5                                         Granules and Pellets                                                                        0.1-95      5-99.9  0-15                                        High Strength 90-99      0-10     0-2                                         Compositions                                                                  ______________________________________                                         *Active ingredient plus at least one of a Surfactant or a Diluent equals      100 weight percent.                                                      

Lower or higher levels of active ingredient can, of course, be presentdepending on the intended use and the physical properties of thecompound. Higher ratios of surfactant to active ingredient are sometimesdesirable, and are achieved by incorporation into the formulation or bytank mixing.

Typical solid diluents are described in Watkins, et al., "Handbook ofInsecticide Dust Diluents and Carriers", 2nd Ed., Dorland Books,Caldwell, N.J., but other solids, either mined or manufactured, may beused. The more absorptive diluents are preferred for wettable powdersand the denser ones for dusts. Typical liquid diluents and solvents aredescribed in Marsden, "Solvents Guide," 2nd Ed., Interscience, New York,1950. Solubility under 0.1% is preferred for suspension concentrates;solution concentrates are preferably stable against phase separation at0° C. "McCutcheon's Detergents and Emulsifiers Annual", MC PublishingCorp., Ridgewood, N.J., as well as Sisely and Wood, "Encyclopedia ofSurface Active Agents", Chemical Publishing Co., Inc., New York, 1964,list surfactants and recommended uses. All formulations can containminor amounts of additives to reduce foaming, caking, corrosion,microbiological growth, etc.

The methods of making such compositions are well known. Solutions areprepared by simply mixing the ingredients. Fine solid compositions aremade by blending and, usually, grinding as in a hammer or fluid energymill. Suspensions are prepared by wet milling (see, for example,Littler, U.S. Pat. No. 3,060,084). Granules and pellets may be made byspraying the active material upon preformed granular carriers or byagglomeration techniques. See J. E. Browning, "Agglomeration", ChemicalEngineering, Dec. 4, 1967, pp. 147ff. and "Perry's Chemical Engineer'sHandbook", 5th Ed., McGraw-Hill, New York, 963, pp. 8-57ff.

For further information regarding the art of formulation, see forexample:

H. M. Loux, U.S. Pat. No. 3,235,361, Feb. 15, 1966, Col. 6, line 16through Col. 7, line 19 and Examples 10 through 41;

R. W. Luckenbaugh, U.S. Pat. No. 3,309,192, Mar. 14, 1967, Col. 5, line43 through Col. 7, line 62 and Examples 8, 12, 15, 39, 41, 52, 53, 58,132, 138-140, 162-164, 166, 167 and 169-182;

H. Gysin and E Knusli, U.S. Pat. No. 2,891,855, Jun. 23, 1959, Col. 3,line 66 through Col. 5, line 17 and Examples 1-4;

G. C. Klingman, "Weed Control as a Science", John Wiley and Sons, Inc.,New York, 1961, pp. 81-96; and

J. D. Fryer and S. A. Evans, "Weed Control Handbook", 5th Ed., BlackwellScientific Publications, Oxford, 1968, Pp. 101-103.

In the following examples, all parts are by weight unless otherwiseindicated.

EXAMPLE 24 High Strength Concentrate

    ______________________________________                                        N2-[(4,6-Dimethoxypyrimidin-2-yl)aminocarbonyl]-                                                           99%                                              N3-methyl-2,3-pyridinedisulfonamide                                           trimethylnonyl polyethylene glycol ether                                                                    1%                                              ______________________________________                                    

The surfactant is sprayed upon the active ingredient in a blender andthe mixture sifted through a U.S.S. no. 40 sieve (0.42 mm openings)prior to packaging. The concentrate may be formulated further forpractical use.

EXAMPLE 25 Wettable Powder

    ______________________________________                                        2-[[(4,6-Dimethoxypyrimidin-2-yl)aminocarbonyl]-                                                           65%                                              aminosulfonyl]-3-pyridinecarboxylic acid,                                     methyl ester                                                                  dodecylphenol polyethylene glycol ether                                                                     2%                                              sodium ligninsulfonate        4%                                              sodium silicoaluminate        6%                                              montmorillonite (calcined)   23%                                              ______________________________________                                    

The ingredients are thoroughly blended. The liquid surfactant is addedby spraying upon the solid ingredients in the blender. After grinding ina hammer mill to produce particles essentially all below 100 microns,the material is reblended and sifted through a U.S.S. No. 50 sieve (0.3mm opening) and packaged.

EXAMPLE 26 Aqueous Suspension

    ______________________________________                                        N2-[(4,6-Dimethoxypyrimidin-2-yl)aminocarbonyl]-                                                          40.0%                                             N3-methyl-2,3-pyridinedisulfonamide                                           polyacrylic acid thickener   0.3%                                             dodecylphenol polyethylene glycol ether                                                                    0.5%                                             disodium phosphate           1%                                               monosodium phosphate         0.5%                                             polyvinyl alcohol            1.0%                                             water                       56.7%                                             ______________________________________                                    

The ingredients are blended and ground together in a sand mill toproduce particles essentially all under 5 microns in size.

EXAMPLE 27 Oil Suspension

    ______________________________________                                        N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3-(1-                                                       35%                                              propylsulfonyl)-2-pyridinesulfonamide                                         methyl ester                                                                  blend of polyalcohol carboxylic esters                                                                      6%                                              and oil soluble petroleum sulfonates                                          xylene                       59%                                              ______________________________________                                    

The ingredients are combined and ground together in a sand mill toproduce particles essentially all below 3 microns. The product can beused directly, extended with oils, or emulsified in water.

EXAMPLE 28 Oil Suspension

    ______________________________________                                        N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-                                                           25%                                               3-(1-methylsulfonyloxy)-2-pyridinesulfonamide                                 methyl ester                                                                  polyoxyethylene sorbitol hexaoleate                                                                        5%                                               highly aliphatic hydrocarbon oil                                                                          70%                                               ______________________________________                                    

The ingredients are ground together in a sand mill until the solidparticles have been reduced to under about 5 microns. The resultingthick suspension may be applied directly, but preferably after beingextended with oils or emulsified in water.

EXAMPLE 29 Aqueous Suspension

    ______________________________________                                        N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-                                                           25%                                               3-(1-ethylsulfonyl)-2-pyridinesulfonamide                                     methyl ester                                                                  hydrated attapulgite         3%                                               crude calcium ligninsulfonate                                                                             10%                                               sodium dihydrogen phosphate  0.5%                                             water                       61.5%                                             ______________________________________                                    

The ingredients are ground together in a ball or roller mill until thesolid particles have been reduced to diameters under 10 microns.

EXAMPLE 29 Wettable Powder

    ______________________________________                                        N2-[(4,6-Dimethoxypyrimidin-2-yl)aminocarbonyl]-                                                          40.0%                                             N3-methyl-2,3-pyridinedisulfonamide                                           dioctyl sodium sulfosuccinate                                                                              1.5%                                             sodium ligninsulfonate       3%                                               low viscosity methyl cellulose                                                                             1.5%                                             attapulgite                 54%                                               ______________________________________                                    

The ingredients are thoroughly blended, passed through an air mill, toproduce an average particle size under 15 microns, reblended, and siftedthrough a U.S.S. No. 50 sieve (0.3 mm opening) before packaging.

All compounds Of the invention may be formulated in the same manner.

EXAMPLE 30 Granule

    ______________________________________                                        wettable powder of Example 29                                                                           15%                                                 gypsum                    69%                                                 potassium sulfate         16%                                                 ______________________________________                                    

The ingredients are blended in a rotating mixer and water sprayed on toaccomplish granulation. When most of the material has reached thedesired range of 1.0 to 0.42 cm (U.S.S.#18 to 40 sieves), the granulesare removed, dried, and screened. Oversized material is crushed toproduce additional material in the desired range. These granules contain% active ingredient.

EXAMPLE 31 Wettable Powder

    ______________________________________                                        N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl-                                                            50%                                               3-(ethylsulfonyl)-2-pyridinesulfonamide                                       methyl ester                                                                  sodium alkylnaphthalenesulfonate                                                                           2%                                               low viscosity methyl cellulose                                                                             2%                                               diatomaceous earth          46%                                               ______________________________________                                    

The ingredients are blended, coarsely hammermilled and the air milled toproduce particles of active essentially all below 10 microns indiameter. The product is reblended before packaging.

EXAMPLE 32 Extruded Pellet

    ______________________________________                                        N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl-                                                            25%                                               3-(ethylsulfonyl)-2-pyridinesulfonamide                                       anhydrous sodium sulfate    10%                                               crude calcium ligninsulfonate                                                                              5%                                               sodium alkylnaphthalenesulfonate                                                                           1%                                               calcium/magnesium bentonite 59%                                               ______________________________________                                    

The ingredients are blended, hammer-milled and then moistened with about12% water. The mixture is extruded as cylinders about 3 mm diameterwhich are cut to produce pellets about 3 mm long. These may be useddirectly after drying, or the dried pellets may be crushed to pass aU.S.S. No. 20 sieve (0.84 mm openings). The granules held on a U.S.S.No. 40 sieve (0.42 mm openings) may be packaged for use and the finesrecycled.

EXAMPLE 33 Wettable Powder

    ______________________________________                                        N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-                                                           80%                                               3-(1-ethylsulfonyl)-2-pyridinesulfonamide                                     sodium alkylnaphthalenesulfonate                                                                           2%                                               sodium ligninsulfonate       2%                                               synthetic amorphous silica   3%                                               kaolinite                   13%                                               ______________________________________                                    

The ingredients are blended and then ground in a hammermill to produceparticles with an average particle size less than 25 microns indiameter. The material is reblended and sifted through a U.S.S. No. 50sieve (0.3 mm opening) before being packaged.

EXAMPLE 34 High Strength Concentrate

    ______________________________________                                        N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-                                                           98.5%                                             3-(1-ethylsulfonyl)-2-pyridinesulfonamide                                     silica aerogel               0.5%                                             synthetic amorphous fine silica                                                                            1.0%                                             ______________________________________                                    

The ingredients are blended and ground in a hammer mill to produce ahigh strength concentrate essentially all passing a U.S.S. No. 50 sieve(0.3 mm openings). This material may then be formulated in a variety ofways.

EXAMPLE 35 Wettable Powder

    ______________________________________                                        2-[[(4,6-Dimethoxypyrimidin-2-yl)aminocarbonyl]-                                                           80%                                              aminosulfonyl]-3-pyridinecarboxylic acid,                                     methyl ester                                                                  sodium alkylnaphthalenesulfonate                                                                            2%                                              sodium ligninsulfonate        2%                                              synthetic amorphous silica    3%                                              kaolinite                    13%                                              ______________________________________                                    

The ingredients are blended and then ground in a hammermill to produceparticles with an average particle size less than 25 microns indiameter. The material is reblended and sifted through a U.S.S. No. 50sieve (0.3 mm opening) before being packaged.

EXAMPLE 36 High Strength Concentrate

    ______________________________________                                        N2-[(4,6-Dimethoxypyrimidin-2-yl)aminocarbonyl]-                                                          98.5%                                             N3-methyl-2,3-pyridinedisulfonamide                                           silica aerogel               0.5%                                             synthetic amorphous fine silica                                                                            1.0%                                             ______________________________________                                    

The ingredients are blended and ground in a hammer mill to produce ahigh strength concentrate essentially all passing a U.S.S. No. 50 sieve(0.3 mm openings). This material may then be formulated in a variety ofways.

Utility

Test results indicate that the compounds of the present invention arehighly active preemergent and/or postemergent herbicides or plant growthregulants. Many of them have utility for broad-spectrum pre- and/orpostemergence weed control in areas where complete control of allvegetation is desired, such as around fuel storage tanks, industrialstorage areas, parking lots, drive-in theaters, around billboards,highway and railroad structures. Some of the compounds have utility forselective weed control in plantation crops, Solanaceae family crops suchas tomatoes, potatoes and peppers, other crops such as wheat, barley,corn, cotton or soybeans, and their fallow land. In particular, somecompounds of this invention control weeds in corn (maize) both pre- andpostemergence without significant crop damage. Some compounds of thisinvention also control weeds in potato (Solanum tuberosum) and tomato(Lycoperiscon esculentum) without significant crop damage. Thesecompounds are particularly useful to control such problem weeds asfoxtail (Setaria spp.), fall panicum (Panicum dichotomiflorum),barnyardgrass (Echinochloa crusgalli), (seedling johnsongrass (Sorghumhalepense) and shattercane (Sorghum bicolor). They can be usedpreemergence or postemergence and are most effective when appliedpostemergence to young weeds. They are also effective on certainbroadleaf weeds such as lambsquarters (Chenopodium album), pigweed(Amaranthus spp.) and velvetleaf (Abutilon theophrasti).

Alternatively, the subject compounds are useful to modify plant growthand as citrus abscission agents.

Rates of application for compounds of this invention are determined by anumber of factors, including their use as plant growth modifiers or asherbicides, crop species involved, types of weeds to be controlled,weather and climate, formulations selected, mode of application, amountof foliage present, etc. In general terms, the subject compounds shouldbe applied at levels of around 0.001 to 20 kg/ha, the lower rates beingsuggested for use on lighter soils and/or those having a low organicmatter content, for plant growth modification or for situations whereonly short-term persistence is required.

Compounds of this invention may be used in combination with any othercommercial herbicide, examples of which are those of the triazine,triazole, imidazolinone, uracil, urea, amide, diphenylether, cineole,carbamate and bipyridylium types. They are particularly useful incombination with the following herbicides.

                  chloro-4-(ethylamino)-6-                                                  Chemical Name                                                       ______________________________________                                        Common Name                                                                   alachlor    2-chloro-2',6'-diethyl-N-(methoxymethyl)-                                     acetanilide                                                       atrazine    2-chloro-4-(ethylamino)-6 -(isopropyl-                                        amino)- .sub.-s-triazine                                          butylate    s-ethyl-diisobutylthiocarbamate                                   cyanazine   2-[[4-chloro-6-(ethylamino)- .sub.-s-triazin-2-                               yl]amino]-2-methylpropionitrile                                   dicamba     3,6-dichloro- -o-anisic acid                                      EPTC        S-ethyl dipropylthiocarbamate                                     linuron     3-(3,4-dichlorophenyl)-1-methoxy-1-                                           methylurea                                                        metolachlor 2-chloro-N-(2-ethyl-6-methylphenyl)-N-                                        (2-methoxy-1-methylethyl)acetamide                                metribuzin  4-amino-6-tert-butyl-3-(methylthio)-as-                                       triazine-5(4H)-one                                                tridiphane  2-(3,5-dichlorophenyl)-2-(2,2,2-tri-                                          chloroethyl)oxirane                                               2,4-D       (2,4-dichlorophenoxy)acetic acid                                  bromoxynil  3,5-dibromo-4-hydroxyphenylcyanide                                paraquat    1,1'-dimethyl-4,4-bipyridinium ion                                glyphosate  N-(phosphonomethyl)glycine                                        DCPA        dimethyl tetrachloroterephthalate                                 dalapon     2,2-dichloropropionic acid                                        dinoseb     2-(1-methylpropyl)-4,6-dinitrophenol                              diphenamid  N,N-dimethyl-2,2-diphenylacetamide                                pendimethalin                                                                             N-(1-ethylpropyl)-3,4-dimethyl-2,6-                                           dinitrobenamine                                                   oryzalin    3,5-dinitro-N,N-dipropylsulfanilamide                             trifluralin α,α,α-trifluoro-2,6-dinitro-N,N-                            dipropyl-p-toluidine                                              chloramben  3-amino-2,5-dichlorobenzoic acid                                  napropamide 2-(α-naphthoxy)-N,N-diethylpropion-                                     amide                                                             pebulate    S-propyl butylethylthiocarbamate                                  chlorpropham                                                                              isopropyl m-chlorocarbanilate                                     bensulide   S-(O,O-diisopropyl phosphorodithioate)                                        ester of N-(2-mercaptoethyl)benzene-                                          sulfonamide                                                       Trade Name                                                                    Harmony ®                                                                             3-[[(4-methoxy-6-methyl-1,3,5-triazin-                                        2-yl)aminocarbonyl]aminosulfonyl]-2-                                          thiophenecarboxylic acid, methyl ester                            Cinch ® 1-methyl-4-(1-methylethyl)-2-exo-[(2-                                         methylphenyl)-methoxy]-7-oxabicyclo-                                          [2.2.1]heptane                                                    --          2-ethoxy-N-[[4-(2,2,2-trifluoroethoxy)-                                       6-methoxy-1,3,5-triazin-2-yl]amino-                                           carbonyl]benzenesulfonamide                                       ______________________________________                                    

Herbicidal properties of the subject compounds were discovered in aseries of greenhouse tests. Test procedures and results follow.

    __________________________________________________________________________    Compounds                                                                      ##STR55##                                                                    Compound                                                                            R.sub.2    R  R.sub.1                                                                           X     Y    Z                                          __________________________________________________________________________     1    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                          2    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  H   CH.sub.3                                                                            OCH.sub.3                                                                          CH                                          3    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  H   Cl    OCH.sub.3                                                                          CH                                          4    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  H   CH.sub.3                                                                            CH.sub.3                                                                           CH                                          5    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          N                                           6    SO.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      H  H   CH.sub.3                                                                            OCH.sub.3                                                                          N                                           7    SO.sub.2 CH.sub. 2 CH.sub.2 CH.sub.3                                                     H  H   OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                           8    S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                          9    S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H  H   CH.sub.3                                                                            OCH.sub.3                                                                          CH                                         10    S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H  H   Cl    OCH.sub.3                                                                          CH                                         11    S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H  H   CH.sub.3                                                                            CH.sub.3                                                                           CH                                         12    S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          N                                          13    S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H  H   CH.sub.3                                                                            OCH.sub.3                                                                          N                                          14    S(O)CH.sub.2 CH.sub.2 CH.sub.3                                                           H  H   OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                         N                                          15    S(O)CH.sub.2 CH.sub.3                                                                    H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         16    S(O)CH.sub.2 CH.sub.3                                                                    H  H   OCH.sub.3                                                                           CH.sub.3                                                                           CH                                         17    S(O)CH.sub.2 CH.sub.3                                                                    H  H   Cl    OCH.sub.3                                                                          CH                                         18    S(O)CH.sub.2 CH.sub.3                                                                    H  H   CH.sub.3                                                                            CH.sub.3                                                                           CH                                         19    S(O)CH.sub.2 CH.sub.3                                                                    H  H   OCH   OCH.sub.3                                                                          N                                          20    S(O)CH.sub.2 CH.sub.3                                                                    H  H   OCH.sub.3                                                                           CH.sub.3                                                                           N                                          21    S(O)CH.sub.2 CH.sub.3                                                                    H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         22    SO.sub.2 CH.sub.2 CH.sub.3                                                               H  H   OCH.sub.3                                                                           CH.sub.3                                                                           CH                                         23    SO.sub.2 CH.sub.2 CH.sub.3                                                               H  H   Cl    OCH.sub.3                                                                          CH                                         24    SO.sub.2 CH.sub.2 CH.sub.3                                                               H  H   CH.sub.3                                                                            CH.sub.3                                                                           CH                                         25    SO.sub.2 CH.sub.2 CH.sub.3                                                               H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          N                                          26    SO.sub.2 CH.sub.2 CH.sub.3                                                               H  H   OCH.sub.3                                                                           CH.sub.3                                                                           N                                          27    SO.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                         H   OCH.sub.3                                                                           CH.sub.3                                                                           N                                          28    S(O)CH.sub.3                                                                             H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         29    S(O)CH.sub.3                                                                             H  H   OCH.sub.3                                                                           CH.sub.3                                                                           CH                                         30    S(O)CH.sub.3                                                                             H  H   Cl    OCH.sub.3                                                                          CH                                         31    S(O)CH.sub.3                                                                             H  H   CH.sub.3                                                                            CH.sub.3                                                                           CH                                         32    S(O)CH.sub.3                                                                             H  H   OCH.sub.3                                                                           CH.sub.3                                                                           N                                          33    S(O)CH.sub.3                                                                             CH.sub.3                                                                         H   OCH.sub.3                                                                           CH.sub.3                                                                           N                                          34    SO.sub.2 CH.sub.3                                                                        H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         35    SO.sub.2 CH.sub.3                                                                        H  H   OCH.sub.3                                                                           CH.sub.3                                                                           CH                                         36    SO.sub.2 CH.sub.3                                                                        H  H   Cl    OCH.sub.3                                                                          CH                                         37    SO.sub.2 CH.sub.3                                                                        H  H   CH.sub.3                                                                            CH.sub.3                                                                           CH                                         38    SO.sub.2 CH.sub.3                                                                        H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          N                                          39    SO.sub.2 CH.sub.3                                                                        H  H   OCH.sub.3                                                                           CH.sub.3                                                                           N                                          40    S(O)CH(CH.sub.3).sub.2                                                                   H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         41    S(O)CH(CH.sub.3).sub.2                                                                   H  H   OCH.sub.3                                                                           CH.sub.3                                                                           CH                                         42    S(O)CH(CH.sub.3).sub.2                                                                   H  H   Cl    OCH.sub.3                                                                          CH                                         43    S(O)CH(CH.sub.3).sub.2                                                                   H  H   CH.sub.3                                                                            CH.sub.3                                                                           CH                                         44    S(O)CH(CH.sub.3).sub.2                                                                   H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          N                                          45    S(O)CH(CH.sub.3).sub.2                                                                   H  H   OCH.sub.3                                                                           CH.sub.3                                                                           N                                          46    SO.sub.2 CH(CH.sub.3).sub.2                                                              H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         47    SO.sub.2 CH(CH.sub.3).sub.2                                                              H  H   OCH.sub.3                                                                           CH.sub.3                                                                           CH                                         48    SO.sub.2 CH(CH.sub.3).sub.2                                                              H  H   Cl    OCH.sub.3                                                                          CH                                         49    SO.sub.2 CH(CH.sub.3).sub.2                                                              H  H   CH.sub.3                                                                            CH.sub.3                                                                           CH                                         50    SO.sub.2 CH(CH.sub.3).sub.2                                                              H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          N                                          51    SO.sub.2 CH(CH.sub.3).sub.2                                                              H  H   OCH.sub.3                                                                           CH.sub.3                                                                           N                                          52    SO.sub.2 CH(CH.sub.3).sub.2                                                              CH.sub.3                                                                         H   OCH.sub.3                                                                           CH.sub.3                                                                           N                                          53    SO.sub.2 (CH.sub.2).sub.3 CH.sub.3                                                       H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         54    SO.sub.2 (CH.sub.2).sub.3 CH.sub.3                                                       H  H   OCH.sub.3                                                                           CH.sub.3                                                                           CH                                         55    SO.sub.2 (CH.sub.2).sub.3 CH.sub.3                                                       H  H   Cl    OCH.sub.3                                                                          CH                                         56    SO.sub.2 (CH.sub.2).sub.3 CH.sub.3                                                       H  H   CH.sub.3                                                                            CH.sub.3                                                                           CH                                         57    SO.sub.2 (CH.sub.2).sub.3 CH.sub.3                                                       H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          N                                          58    SO.sub.2 (CH.sub.2).sub.3 CH.sub.3                                                       H  H   OCH.sub.3                                                                           CH.sub.3                                                                           N                                          59    SO.sub.2 (CH.sub.2).sub.3 CH.sub.3                                                       CH.sub.3                                                                         H   OCH.sub.3                                                                           CH.sub.3                                                                           N                                          60    SO.sub.2 CH.sub.2 CH.sub.3                                                               H  CH.sub.3                                                                          OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         61    SO.sub.2 CH.sub.2 CH.sub.3                                                               H  CH.sub.3                                                                          OCH.sub.3                                                                           CH.sub.3                                                                           CH                                         62    SO.sub.2 CH.sub.2 CH.sub.3                                                               H  CH.sub.3                                                                          CH.sub.3                                                                            CH.sub.3                                                                           CH                                         63    SO.sub.2 CH.sub.2 CH.sub.3                                                               H  CH.sub.3                                                                          OCH.sub.3                                                                           CH.sub.3                                                                           N                                          64    SO.sub.2 CH.sub.2 CH.sub.3                                                               H  OCH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         65    OSO.sub.2 CH.sub.3                                                                       H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         66    OSO.sub.2 CH.sub.3                                                                       H  H   OCH.sub.3                                                                           CH.sub.3                                                                           CH                                         67    OSO.sub.2 CH.sub.3                                                                       H  H   Cl    OCH.sub.3                                                                          CH                                         68    OSO.sub.2 CH.sub.3                                                                       H  H   CH.sub.3                                                                            CH.sub.3                                                                           CH                                         69    OSO.sub.2 CH.sub.3                                                                       H  H   OCH.sub.3                                                                           CH.sub.3                                                                           N                                          70    OSO.sub.2 C.sub.2 H.sub.5                                                                H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         71    OSO.sub.2 C.sub.2 H.sub.5                                                                H  H   CH.sub.3                                                                            OCH.sub.3                                                                          CH                                         72    OSO.sub.2 C.sub.2 H.sub.5                                                                H  H   Cl    OCH.sub.3                                                                          CH                                         73    OSO.sub.2 C.sub.2 H.sub.5                                                                H  H   CH.sub.3                                                                            CH.sub.3                                                                           CH                                         74    OSO.sub.2 C.sub.2 H.sub.5                                                                H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          N                                          75    OSO.sub.2 C.sub.2 H.sub.5                                                                H  H   CH.sub.3                                                                            OCH.sub.3                                                                          N                                          76    SO.sub.2 C.sub.2 H.sub.5                                                                 H  F   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         77    SO.sub.2 C.sub.2 H.sub.5                                                                 H  F   CH.sub.3                                                                            CH.sub.3                                                                           CH                                         78    SO.sub.2 C.sub.2 H.sub.5                                                                 H  Cl  OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         79    SO.sub.2 C.sub.2 H.sub.5                                                                 H  Cl  Cl    OCH.sub.3                                                                          CH                                         80    SO.sub.2 C.sub.2 H.sub.5                                                                 H  Cl  CH.sub.3                                                                            CH.sub.3                                                                           CH                                         81    OSO.sub.2 CF.sub.3                                                                       H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         82    OSO.sub.2 CF.sub.3                                                                       H  H   Cl    OCH.sub. 3                                                                         CH                                         83    OSO.sub.2 CF.sub.3                                                                       H  H   CH.sub.3                                                                            CH.sub.3                                                                           CH                                         84    OSO.sub.2 CF.sub.3                                                                       H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          N                                          85    OSO.sub.2 CF.sub.3                                                                       H  H   CH.sub.3                                                                            OCH.sub.3                                                                          N                                          86    CH.sub.2 Cl                                                                              H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         87    CH.sub.2 Cl                                                                              H  H   Cl    OCH.sub.3                                                                          CH                                         88    CH.sub.2 Cl                                                                              H  H   CH.sub.3                                                                            OCH.sub.3                                                                          N                                          89    P(O)(OCH.sub.2 CH.sub.3).sub.2                                                           H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         90    P(O)(OCH.sub.2 CH.sub.3).sub.2                                                           H  H   CH.sub.3                                                                            OCH.sub.3                                                                          CH                                         91    P(O)(OCH.sub.2 CH.sub.3).sub.2                                                           H  H   CH.sub.3                                                                            CH.sub.3                                                                           CH                                         92    SO.sub.2 NHCH.sub.3                                                                      H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         93    SO.sub.2 NHCH.sub.3                                                                      H  H   Cl    OCH.sub.3                                                                          CH                                         94    SO.sub.2 NHCH.sub.3                                                                      H  H   CH.sub.3                                                                            CH.sub.3                                                                           CH                                         95    SO.sub.2 NHCH.sub.3                                                                      H  H   OCH.sub.3                                                                           CH.sub.3                                                                           N                                          96    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                            H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         97    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                            H  H   CH.sub.3                                                                            CH.sub.3                                                                           CH                                         98    SO.sub.2 N(OCH.sub.3)CH.sub.3                                                            H  H   OCH.sub.3                                                                           CH.sub.3                                                                           N                                          99    SO.sub.2 N(OCH.sub.2)CH.sub.3                                                            CH.sub.3                                                                         H   OCH.sub.3                                                                           CH.sub.3                                                                           N                                          100   SO.sub.2 NHCH.sub.2 CH.sub.3                                                             H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         101   SO.sub.2 NHCH.sub.2 CH.sub.3                                                             H  H   Cl    OCH.sub.3                                                                          CH                                         102   SO.sub.2 NHCH.sub.2 CH.sub.3                                                             H  H   CH.sub.3                                                                            CH.sub.3                                                                           CH                                         103   SO.sub.2 NHCH.sub.2 CH.sub.3                                                             H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          N                                          104   SO.sub.2 NHCH.sub.2 CH.sub.3                                                             H  H   OCH.sub.3                                                                           CH.sub.3                                                                           N                                          105   SO.sub.2 NHCH.sub.2 CH.sub.3                                                             CH.sub.3                                                                         H   OCH.sub.3                                                                           CH.sub.3                                                                           N                                          106   SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                    H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         107   SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                    H  H   CH.sub.3                                                                            OCH.sub.3                                                                          CH                                         108   SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                    H  H   Cl    OCH.sub.3                                                                          CH                                         109   SO.sub.2 NHCH.sub.2 CH.sub.2 CH.sub.3                                                    H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          N                                          110                                                                                  ##STR56## H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         111                                                                                  ##STR57## H  H   CH.sub.3                                                                            CH.sub.3                                                                           CH                                         112   CO.sub.2 CH.sub.2 cyclopropyl                                                            H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         113   CO.sub.2 CH.sub.2 cyclopropyl                                                            H  H   Cl    OCH.sub.3                                                                          CH                                         114   CO.sub.2 CH.sub.2 cyclopropyl                                                            H  H   CH.sub.3                                                                            CH.sub.3                                                                           CH                                         115   CO.sub.2 CH.sub.2 cyclopropyl                                                            H  H   OCH.sub.3                                                                           OCH.sub.3                                                                          N                                          116   CO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                         117   CO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                          CH                                         118   CO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                         Cl    OCH.sub.3                                                                          CH                                         119   CO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                           CH                                         120   CO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                          N                                          121   CO.sub.2 CH.sub.3                                                                        H  OCH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                          N                                          __________________________________________________________________________

Test A

Seeds of large crabgrass (Digitaria sanguinalis), barnyardgrass(Echinochloa crus-galli), giant foxtail (Setaria faberi), wild oats(Avena fatua), cheatgrass (Bromus secalinus), velvetleaf (Abutilontheophrasti), cultivated morningglory (Ipomoea coccinea, variety ScarletO'Hara), cocklebur (Xanthium pensylvanicum) G522 sorghum (Sorghumvulgare, variety Funk G522), G4646 corn (Zea mays, variety Funk G4646),Williams soybeans (Glycine max, variety Williams), USH11 sugarbeet (Betavulgaris, variety Union Sugarbeet Co. USH11), Coker cotton (Gossypiumhirsutum, variety Coker 315), dry seeded rice (Oryza sativa, varietyCalifornia Rice Coop. M101), Era wheat (Triticum aestivum, variety Eraspring), Klages barley (Hordeum vulgare, variety Klages spring) andpurple nutsedge (Cyperus rotundus) tubers were planted and treatedpreemergence with the test chemicals dissolved in a non-phytotoxicsolvent. At the same time, these crop and weed species were treated witha soil/foliage application. At the time of treatment, the plants rangedin height from 2 to 18 cm. Treated plants and controls were maintainedin a greenhouse for sixteen days, after which all species were comparedto controls and visually rated for response to treatment. The ratings,summarized in Table A, are based on a numerical scale extending from0=no injury, to 10=complete kill. The accompanying descriptive symbolshave the following meanings:

C=chlorosis/necrosis;

B=burn;

D=defoliation;

E=emergence inhibition;

G=growth retardation;

H=formative effect;

U=unusual pigmentation;

X=axillary stimulation;

S=albinism; and

6Y=abscised buds or flowers.

"POSOL" and "PRSOL" in Table A denote post- and preemergence treatments,respectively.

    TABLE A      PRSOL CMPD 1 CMPD 2 CMPD 3 CMPD 4 CMPD 5 CMPD 6 CMPD 7 CMPD 8 CMPD 9     CMPD 10 CMPD 11 RATE = KG/HA 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01     0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05     0.01      COKER COTTON  8G  5G 0 0 2G 0 2G 0 0 0 0 0 0 0  4G 3G 1H 0 0 0     2G 0 CULT MORNINGLRY  9G  8H 0 0 5H 1H 1C 0 0 0 0 0 0 0  9G 8H 2C, 8H 1C     3H 0 1H 0 COCKLEBUR  9H  9H 0 0 3G 1C 0 0 0 0 0 0 0 0  8H 3C, 5H -- -- 0     0 4H 0 PURPLE NUTSEDGE 10E  3C, 7G 0 0 9G 8G 0 0 0 -- 0 0 10E 0  9G 3C,     9G 3G 0 0 0 0 0 LARGE CRABGRASS  9G -- 9G 0 9G 5G 8G -- 2G -- -- -- --     --  6G 2C 0 -- 0 0 0 0 BARNYARDGRASS  9H  9H 0 0 3C, 7G 2G 2G 0 2G 0 0 0     0 0  9H 3C, 8H 3C, 8H 2C 3G 0 2G 0 WILD OATS  4C, 8G  1C 0 0 0 4G 2G 0 0     0 0 0 0 0  3C, 8H 6G 4C, 9G 4G 2C, 4G 0 7G 0 ERA WHEAT 10E  8G 0 0 0 0 0     0 0 0 0 0 0 0  8H 6G 4C, 8G 0 0 0 0 0 G4646 CORN  5G  0 0 0 0 2G 2G 0 0     0 0 0 0 0  3C, 7H 0 2G 0 0 0 2G 0 WILLMS SOYBEANS  3G  0 0 0 3G 0 5G 0 0     0 0 0 0 0  3G 5G 3G 1H 0 0 0 0 RICE DRY SEEDED 10E  4C, 9H 0 0 3C, 8G 6G     2C, 5G 0 0 0 0 0 0 0 10E 3C, 9H 4C, 9H 3G 5G 2G 2G 0 G522 SORGHUM 10E     10H 0 0 2C, 9G 3C, 8G 2C 0 0 0 0 0 0 0  5C, 9H 3C, 9H 5C, 9H 3C, 8H 3C,     8H 3C, 7H 3C, 5G 4G CHEAT GRASS  9H  8G 0 0 7G 2G 5G 0 0 0 0 0 0 0  9H     9G 9G 5G 7G 0 4G 0 USH11 SUGARBEET  9G  6G 6G 0 7G 4H 8G 4G 0 -- 0 0 0 0      4C, 9G 3C, 8G 4C, 9G 8H 3C, 3H 0 5H 0 VELVETLEAF  8H  3H 0 0 2G 0 0 0 0     0 0 0 0 0  8H 2C, 2G 2C, 3H 1C 0 0 1H 0 GIANT FOXTAIL  9H  3C, 8G 0 0 2C     0 2G 0 2G 0 0 0 0 0  9H 7G 2C, 3G 0 0 0 0 0 KLAGES BARLEY  8G  7G 0 0 6G     0 0 0 0 0 0 0 0 0      2C, 9G 6G 4C, 9G 0 0 0 2G 0                              PRSOL CMPD 12     CMPD 13 CMPD 14 CMPD 15 CMPD 16 CMPD 17 CMPD 18 CMPD 19 CMPD 20 CMPD 21     CMPD 22 RATE = KG/HA 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01     0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01       COKER COTTON 5G 0 0 0 0 0  3C, 9G  8G  5G 0 0 0 0 0 0 0 0 0  9G  8G 0     0 CULT MORNINGLRY 0 0 0 0 0 0  9G  2C, 9H  3C, 7H 0 2C, 3H 0 0 0 0 0 0 0      9G  8G 2G 0 COCKLEBUR 1H 0 0 0 0 0  8H  2H  1C, 2G 0 0 0 -- 0 0 0 -- 0     9H  8G 0 0 PURPLE NUTSEDGE 0 0 0 0 0 0 10E  9C  3G 0 8G 0 8G 0 0 0 0 0     10E  5G 0 0 LARGE CRABGRASS 0 0 0 0 0 0  9H  2G  2G 0 3G 0 0 0 0 0 0 --     9H 0  0 0 BARNYARDGRASS 0 0 0 0 0 0  9H  4C, 8H  3G 0 7G 0 2C 0 2G 0 0 0      9H  9H 0 0 WILD OATS 0 0 0 0 0 0  3C, 7G  6G  2C, 6G 6G 4G 0 7G 2G 0 0     0 0  3C, 7H  6G 0 0 ERA WHEAT 0 0 0 0 0 0  3C, 9H  6G  7G 4G 2G 0 6G 2G     0 0 0 0 5C, 9H  8H 0 0 G4646 CORN 2G 0 0 0 0 0  4G  4G  3G 0 0 2G 0 0 2G     0 0 0  1C, 4G  2G 0 0 WILLMS SOYBEANS 0 0 0 0 0 0  8H  3C, 6H  3C, 7H 0     2C, 2H 0 0 0 2G 0 0 0  9H  3C, 6H 0 0 RICE DRY SEEDED 0 0 0 0 0 0 10H     10H 10H 2C, 4G 9H 2G 8H 2G 0 0 0 0 10E 10H 0 0 G522 SORGHUM 0 0 0 0 0 0     10H  4C, 9H  9H 4C, 9H 9H 3C, 8H 4C, 9H 2C, 7G 0 0 0 0 10E  9H 3G 0     CHEAT GRASS 0 0 0 0 0 0  9H  3C, 9G  3C, 8H 2C, 7H 7G 0 7G 2G 2G 0 0 0     9H  9H 0 0 USH11 SUGARBEET 3H 0 0 0 0 0  3C, 9G  3C, 9G  3C, 8H 2C, 3G     8G 5H 5H 0 2H 0 0 0  9G  9G 3G -- VELVETLEAF 0 0 0 0 0 0  3C, 8G  3C, 6H      2C, 5G 0 3G 0 0 0 0 0 0 0  7H  2G 2G 0 GIANT FOXTAIL 0 00 0 0 0  5C, 9H      2C, 8H  2C 0 2G 0 0 0 0 0 0 0  9H  9H 0 0 KLAGES BARLEY 0 0 0 0 0 0     3C, 8G  7G  2C, 7G 2G 5G 0 3G 1C 0 0 0 0  9G      8G 0 0                       PRSOL CMPD 23 CMPD 24 CMPD 25 CMPD 26 CMPD     27 CMPD 28 CMPD 29 CMPD 30 CMPD 31 CMPD 32 CMPD 33 RATE = KG/HA 0.05     0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05     0.01 0.05 0.01 0.05 0.01 0.05 0.01       COKER COTTON  6G  3G 0 0 0 0 0 0 0 0  8G 6G 5G 3G 0 0 2G 0 4G 0 0 0     CULT MORNINGLRY  9G  2G 1C 0 1C, 1H 0 0 0 0 0  7H 7H 3G 0 3C, 7G 2G 2G 0     2G 0 0 0 COCKLEBUR  8G  0 5G 0 -- 0 0 0 0 --  1H -- 0 0 2C, 3H 0 7G 0 0     0 -- 0 PURPLE NUTSEDGE 10E  7G 0 0 0 0 0 0 0 0 10E 3G 4G 0 0 0 0 0 0 0 0     0 LARGE CRABGRASS  6G  0 0 0 0 -- 0 -- 0 0  2C, 8G 8G -- -- -- -- -- 0 0     0 0 0 BARNYARDGRASS  9H  3C, 8H 0 0 0 0 0 0 0 0  9H 2C, 6G 2G 0 0 0 0 0     0 0 0 0 WILD OATS  4G  0 0 0 0 0 0 0 0 0  3C, 8G 3C, 7G 3G 0 0 0 2G 0 5G     0 0 0 ERA WHEAT  5G  0 0 0 0 0 0 0 0 0  3C, 9G 3C, 8G 2G 0 0 0 4G 0 2G 0     0 0 G4646 CORN  2G  0 0 0 0 0 0 0 0 0  2C, 8G 3C, 7G 2C, 4G 0 2C 0 3G 0     0 0 0 0 WILLMS SOYBEANS  2G  0 0 0 0 0 0 0 0 0  3C, 7H 3C, 7H 3C, 3H 2G     2C, 2H 2H 4G 0 2G 0 0 0 RICE DRY SEEDED 10E  9H 0 0 0 0 0 0 0 0  9H 9H     3C, 6G 2C, 3G 2G 2G 2G 0 0 0 0 0 G522 SORGHUM 10E 10H 3G 0 2G 0 0 0 2C 0      5C, 9H 5C, 9H 4C, 5G 2G 2C 0 2G 0 0 0 0 0 CHEAT GRASS  9H  7H 0 0 0 0 0     0 0 0  2C, 8G 8G 3G 2G 0 0 0 0 2G 0 0 0 USH11 SUGARBEET  8G  3H 0 0 5G     -- 0 0 3H 0  4C, 9G 1C 7G 5H 7G 2H 2H 0 2H 0 5H 3G VELVETLEAF  2G  0 0 0     2G 0 0 0 0 0  7G 3G 2G 0 4G 0 0 0 0 0 3G 0 GIANT FOXTAIL  7H  3G 0 0 0 0     0 0 0 0  9H 7G 8G 0 5G 5G 2G 0 0 0 0 0 KLAGES BARLEY  4C, 9G  2G 0 00 0     0 0 0 0      2C, 7G 8G 2C, 6G 0 2C 0 0 0 0 0 0 0                               PRSOL C     MPD 34 CMPD 35 CMPD 36 CMPD 37 CMPD 38 CMPD 39 CMPD 40 CMPD 41 CMPD 42     CMPD 43 CMPD 44 RATE = KG/HA 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01     0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05     0.01      COKER COTTON  8G  8G 4G --  8G 4G 0 0 0 0 0 0 2C, 5G 2G 0 0 0     0 0 0 0 0 CULT MORNINGLRY  9G  8G 0 2C  7G 0 0 0 0 0 0 0 9H 7H 2C, 7H     2C, 5H 0 0 0 0 0 0 COCKLEBUR  8H -- 0 0  2G 0 0 0 0 0 0 0 8H 3H 2C, 4H     3G 0 0 0 0 0 0 PURPLE NUTSEDGE 10E  9G 0 0  9G 0 0 0 0 0 0 0 7G 7G 0 0     4G 0 0 0 0 0 LARGE CRABGRASS  4C, 9H 10E 0 0 10E 8G -- 0 0 -- -- -- 9G     4G 3G -- 4G -- 0 0 0 0 BARNYARDGRASS  9H  3C, 8H 0 0  9H 2G 0 0 0 0 0 0     5G 4G 7G 0 0 0 0 0 0 0 WILD OATS  3C, 8H  6G 0 0  0 4G 0 0 0 0 0 0 3C,     7G 3G 2C, 6G 0 0 0 0 0 0 0 ERA WHEAT  4C, 9H  8G 0 0  2G 3G 0 0 0 0 0 0     8G 3G 2C, 7G 0 0 0 0 0 0 0 G4646 CORN  9G  2C, 4G 0 0  0 0 0 0 0 0 0 0     3C, 3G 3G 0 0 0 0 0 0 0 0 WILLMS SOYBEANS  9G  3C, 6G 2G 2C  2C, 4G 0 0     0 0 0 0 0 3C, 3H 2H 2C, 2G 0 2G 0 0 0 0 0 RICE DRY SEEDED 10H 10H 3G 0     10E 2C, 5G 0 0 0 0 0 0 9H 5G 3C, 5G 0 0 0 0 0 0 0 G522 SORGHUM  9G  9G     2G 0 10E 3C, 6H 0 0 0 0 0 0 5C, 9G 3C, 7H 3C, 5G 2C 3C, 3G 0 0 0 0 0     CHEAT GRASS  9H  6G 0 0  7G 2G 0 0 0 0 0 0 8G 5G 7G 0 0 0 0 0 0 0 USH11     SUGARBEET  9G  7G 0 --  7G 4G 0 0 0 0 -- 0 3C, 8H 6H 3C, 5G 3G 0 0 0 0 0     0 VELVETLEAF  3C, 8G  2C, 8G 0 0  1C, 3G 2C 0 0 0 0 0 0 7H 1C 7G 0 0 0 0     0 0 0 GIANT FOXTAIL  9H  9H 0 0  9H 4G 0 0 -- -- 0 0 9H 0 9H 5G 3G 0 2G     0 0 0 KLAGES BARLEY  3C, 8G  8G 0 0  2G 0 0 0 0 0 0 0 2C, 8G 7G 7G 2G 3G     0 0 0 0 0       PRSOL CMPD 45 CMPD 46 CMPD 47 CMPD 48 CMPD 49 CMPD 50 CMPD 51 CMPD 52     CMPD 53 CMPD 54 CMPD 55 CMPD 56 RATE = KG/HA 0.05 0.01 0.05 0.01 0.05     0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05     0.01 0.05 0.01 0.05 0.01       COKER COTTON 0 0  3C, 5H  2C, 4G 0 0 1C 0 0 0 0 0 0 -- 2G 0 0 0 0 0     CULT MORNINGLRY 0 0  9H  1C 0 0 0 0 0 0 0 0 1H 0 1H 1H 4H 0 0 0 0 -- 0 0     COCKLEBUR 0 0  9H  0 0 0 1H -- 0 0 0 0 0 0 -- 0 2H 0 4G 0 0 0 3G 0     PURPLE NUTSEDGE 0 0 10E 10E 4G 0 0 -- 0 0 -- 0 0 0 0 0 0 0 0 0 0 0 0 0     LARGE CRABGRASS 0 0  9H  0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0     BARNYARDGRASS 0 0  2C, 9H  3C, 7H 0 0 0 0 0 0 0 0 0 0 2H 0 4G 0 0 0 0 0     0 0 WILD OATS 0 0  2C, 4G  4G 0 0 0 0 0 0 0 0 0 0 0 0 6G 0 0 0 0 0 0 0     ERA WHEAT 0 0  9H  7G 0 0 0 0 0 0 0 00 0 0 0 5G 0 0 0 0 0 0 0 G4646 CORN     0 0  5G  0 0 0 2G 0 0 0 0 0 0 0 0 0 2G 0 0 0 0 0 0 0 WILLMS SOYBEANS 0 0      3C, 9H  1C, 2H 0 0 2G 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 RICE DRY SEEDED     0 0  9H  4C, 8H 0 0 3C, 9H 2C, 3G 0 0 0 0 6G 0 0 0 0 0 0 0 G522 SORGHUM     0 0  9H  3C, 9H 0 0 2C, 8H 2C, 4G 0 0 0 0 0 0 2G 0 2C, 6G 0 0 0 0 0 0 0     CHEAT GRASS 0 0  9H  7G 0 0 2G 0 0 0 0 0 0 0 0 0 7G 0 0 0 0 0 0 0 USH11     SUGARBEET 0 0  4C, 8G  3H 4H 0 2C, 4H 2H 0 0 0 0 0 0 1H 0 6G 0 0 0 0 0 0     0 VELVETLEAF 0 0  3C, 8G  1C, 4H 0 0 0 0 0 0 0 0 0 0 1H 0 0 0 2G 0 0 0     3G 0 GIANT FOXTAIL 0 0  3C, 9H  8G 0 0 3G 0 0 0 3G 0 0 0 2G 0 3G 0 0 0 0     0 0 0 KLAGES BARLEY 0 0  2C, 9H  2C, 9H 0 0 5G 0 0 0 0 0 0 0 0 0 8G 0 0     0 0 0 0 0       PRSOL CMPD 57 CMPD 58 CMPD 59 CMPD 60 CMPD 61 CMPD 62 CMPD 63 CMPD 64     CMPD 65 CMPD 66 CMPD 67 RATE = KG/HA 0.05 0.01 0.05 0.01 0.05 0.01 0.05     0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05     0.01       COKER COTTON 0 0 0 0 0 0  9G 2G 0 0 0 0 0 0  9G 8G  9G  9G  8G 2G  8G     9G CULT MORNINGLRY 0 0 0 0 0 0  9G 5G 1H 0 0 0 0 0  9G 9G  9H  9H  9G 9G      9G 9H COCKLEBUR 0 0 0 0 0 0  9H 3C, 6G 0 0 0 0 0 --  9H 9H  9H  9H  9G     8G  8G 4G PURPLE NUTSEDGE 0 0 0 -- 0 -- 10E 0 0 0 0 0 4G -- 10E 5G 10E     9G 10E 4C, 9G 10E 10E LARGE CRABGRASS 0 0 0 0 0 0  3C, 7G 0 0 0 0 0 0 0     3C, 8G 3G  5C, 9G  3C, 8G  6C, 9H 3C, 6G  5C, 9H 5C, 9G BARNYARDGRASS 0     0 0 0 0 0  9H 3C,6G 0 0 0 0 0 0  9H 3C, 6G  9H  9H  9H 6G  9H 9H WILD     OATS 0 0 0 0 0 0  2C, 8G 3C, 7G 0 0 0 0 0 0  3C, 7G 2C, 4G  4C, 8G  8G     3C, 7G 2C, 6G  4C, 8G 3C, 7G ERA WHEAT 0 0 0 0 0 0  9H 2C, 9H 0 0 0 0 0     0  3C, 7G 0  4C, 9G  9G  3C, 9G 0  9H 3C, 9G G4646 CORN 0 0 0 0 0 0  2C,     4G 0 2C, 2G 0 0 0 0 0  3C, 9H 2C, 4G  3C, 9H  3C, 9G  3C, 9G 3C, 9H  9H     3C, 9H WILLMS SOYBEANS 0 0 0 0 0 0   9H 3C, 6G 2C, 2H 0 0 0 0 0  9H 3C,     8H  9H  9H  9H 7G  9H 3C, 8G RICE DRY SEEDED 0 0 0 0 0 0 10E 8H 0 0 0 0     2G 0 10E 9H 10E  9H 10E 9H 10E 10E G522 SORGHUM 0 0 0 0 0 0 10H 3C, 8H 0     0 0 0 0 0  9H 3C, 8G 10H  3C, 9H  9H 5G 10C 4C, 9H CHEAT GRASS 0 0 0 0 0     0  9G 6G 0 0 0 0 0 0  8G 2G  9H 10E  9H 8G 10E 8G USH11 SUGARBEET 0 0 0     0 0 0  9G 8G 4G 0 0 0 2H 0  9G 9G  9G  3C, 9G  8G 8G  9G 9G VELVETLEAF 0     0 0 0 0 0  4C, 8G 0 3H 0 0 0 4G 1H  4C, 9G 3C, 6G  9G  9G  7G 7G  4C, 8G     5G GIANT FOXTAIL 0 0 0 0 0 0  3C, 7G 3G 0 0 0 0 0 0  6G 0  9H  9H 10H     3C, 9H  9H 6G KLAGES BARLEY 0 0 0 0 0 0  9G 8G 0 0 0 0 0 0  9G 4G  5C,     9G  3C, 9G  5C, 9H 3G      3C, 9H 3C, 9G                                       PRSOL CMPD 68 CMPD     69 CMPD 70 CMPD 71 CMPD 72 CMPD 73 CMPD 74 CMPD 75 CMPD 76 CMPD 77 RATE     = KG/HA 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0     .01 0.05 0.01 0.05 0.01 0.05 0.01       COKER COTTON  9G 5G 7G 2G  9G 8G  2C, 9G 3G  2C, 7H  2C, 6G  3C, 7H     2C, 2G 2G 0 0 0 0 0 0 0 CULT MORNINGLRY  9G 7G 6G 4G  9G 7G  9G 4G  2C,     9G  9H  9G 8H 0 0 0 0 0 0 0 0 COCKLEBUR  8H 4G 2H 4G  9H 3C, 6H  8H 3C,     6H  3C, 9H  3H  3C, 8H 3C, 2H 0 0 0 0 0 0 0 0 PURPLE NUTSEDGE 10E 9G 0 0     10E 9G 10E 0 10E 10E 10E 3C, 9G 0 0 0 0 0 0 0 0 LARGE CRABGRASS  9C 3C,     8G 3C, 7G 0  4C, 8G 5G  2C, 8G 4G  2C, 7G  2G  4C, 9G 3C, 5G 7G 0 9H 2G     0 0 0 0 BARNYARDGRASS  9H 5G 5G 0  9H 8H  9H 9H  9H  8H  9H 9H 3G 0 3C,     5G 2G 0 0 0 0 WILD OATS  4C, 9G 3C, 6G 2C, 6G 6G  3C, 7G 5G  4C, 8G 2G     3C, 8G  2G  3C, 8H 3C, 8H 6G 0 7G 2G 0 0 0 0 ERA WHEAT  9H 3C, 7G 8G 6G     8H 4G  9H 0  8G  3G  3C, 9H 2C, 9H 7G 0 8G 3G 0 0 0 0 G4646 CORN  3C, 9G     3C, 8G 3C, 8G 5G  9H 9G  2C, 9H 2C, 4G  9G  3C, 7H  3C, 9H 3C, 7H 3C, 7G     2C, 5G 9G 6G 0 00 0 WILLMS SOYBEANS  9H 9H 8G 7G  9H 3C, 7H  9H 3C, 7H     3C, 8H  3C, 5G  3C, 9H 3C, 5H 2G 0 0 0 0 00 0 RICE DRY SEEDED 10E 9H 8G     4G 10E 8G 10E 2C, 5G 10E  9H 10E 9H 7G 0 8G 7G 0 00 0 G522 SORGHUM 10E     3C, 9H 6G 3G  9H 2C, 9G  9H 9H  4C, 9H  3C, 9H  9H 3C, 9G 3C, 8H 2C, 6G     3C, 9G 3C, 8H 0 00 0 CHEAT GRASS 10E 9H 8G 3G  4C, 9G 5G  9H 2C, 7G  9H     7G  3C, 9H 9H 7G 0 8G 3G 0 00 0 USH11 SUGARBEET  5C, 9G 7H 3H 4G  4C, 9G     9G  3C, 9G 3C, 9G  4C, 9G  3C, 8H  4C, 9G 3C, 7H 2H 0 0 2H 0 00 0     VELVETLEAF  9G 2G 2G 0  5C, 9G 5C, 9G  3C, 6G 2G  3C, 7H  3G  3C, 8H 5G     0 0 4G 0 0 00 0 GIANT FOXTAIL 10H 3C, 8G 9H 3G  9H 3C, 7G  9H 2C, 7G     3C, 8H  3G  9H 3C, 7H 7G 2G 3C, 8H 3G 0 00 0 KLAGES BARLEY  5C, 9G 4C,     9G 3C, 9G 2G  9G 2C, 4G  3C, 7G 2C, 4G  2C, 9G  2G  9G 3C, 8H 3C, 7G 0     9G 2G 0 00 0       PRSOL CMPD 78 CMPD 79 CMPD 80 CMPD 81 CMPD 82 CMPD 83 CMPD 84 CMPD 85     CMPD 86 CMPD 87 CMPD 88 CMPD 89 RATE = KG/HA 0.05 0.01 0.05 0.01 0.05     0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05     0.01 0.05 0.01 0.05 0.01       COKER COTTON 0 0 0 0 0 0  8G 0  2G 0 0 0 0 0 0 0 0 0 0 0 0 000 CULT     MORNINGLRY0 0 0 0 0 0  9G 5G  5G 0 0 0 0 0 0 0 2C, 6G 0 0 0 0 000     COCKLEBUR 0 0 0 -- 0 0  9H 3C, 9H  3C, 3G 0  3C, 8H 0 1C 0 0 0 3G 2G0 0     0 0 1H 0 PURPLE NUTSEDGE 0 00 0 0 0 10E 0 10E 0  0 0 0 0 0 0 5G 0 0 0 0     000 LARGE CRABGRASS 0 00 0 0 0  5G 2G  3G 0  0 0 -- 0 0 0 3C, 7G 00 0 0     000 BARNYARDGRASS 0 00 0 0 0  9H 8H  7G 0  0 0 0 0 7G 0 9H 00 0 0 000     WILD OATS 0 00 0 0 0  2G 0  0 0  0 0 0 0 0 0 0 00 0 0 000 ERA WHEAT 0 00     0 0 0  2G 0  0 0  0 0 0 0 0 0 2G 00 0 0 000 G4646 CORN 0 00 0 0 0  5C,     9H 7G  6G 2G  3C, 7G 0 3C, 9G 2G 3C, 9G 2G 3C, 6G 00 0 0 000 WILLMS     SOYBEANS 0 00 0 0 0  5G 2C, 2H  2C, 3G 0  1H 0 2G 0 0 0 3C, 5H 00 0 0     000 RICE DRY SEEDED 0 00 0 0 0 10E 9H 10H 4C, 9H 10H 7H 9H 4G 9H 4G 8G     00 0 0 000 G522 SORGHUM 0 00 0 0 0  5C, 9H 3C, 9H  9H 4C, 9G 10H 5G 2C,     9G 6G 9H 5G 9G 2C0 0 0 000 CHEAT GRASS 0 00 0 0 0  5G 0  3G 0  0 0 0 0 0     0 -- -- -- -- -- -- -- -- USH11 SUGARBEET 0 --0 -- 0 0  9G 8G  7G 5G  6G     2G 3G 2H 3G 2G 9G 5G0 0 0 000 VELVETLEAF 0 00 0 0 0  5H 3C, 5G  3G 0  1H     0 0 0 2G 0 7G 5G0 0 0 000 GIANT FOXTAIL 0 00 0 0 0  8G 7G  3G 0  3G 0 3G     0 7G 2G 5G 00 0 0 000 KLAGES BARLEY 0 00 0 0 0  2C, 9G 3C, 8G  7G 2G     2C, 7G 0 3G 0 2G 0 0 00 0 0 000 DOWNY BROME               -- -- 7G 00 0     0 000       PRSOL CMPD 90 CMPD 91 CMPD 92 CMPD 93 CMPD 94 CMPD 95 CMPD 96 CMPD 97     CMPD 98 CMPD 99 CMPD 100 RATE = KG/HA 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0     .01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05     0.01  COKER COTTON 0 0 0 0  8G  8G  3G  1C 0 0 0 0  2C, 8G 5G 0 0 0 0     2G 0  8H  2C, 6G CULT MORNINGLRY 0 0 0 0  9G   7G  2C, 5H  1C 0 0 0 0     9G 0 0 0 0 0  2C 0  9G  9G COCKLEBUR0 0 0 0 --  5G  3C, 8H  2H 0 0 0 --     8H 2C, 6H -- 0 0 0  2G 0  9H  3C, 7H PURPLE NUTSEDGE0 0 0 0 10E  9G 10E     10E 0 0 0 0  9G 8G0 0 0 0 10E 0 10E  9G LARGE CRABGRASS0 0 0 0  3C, 8G     2G  3C, 5G  0 0 0 0 0 10E 3C, 6G0 0 0 0  0 0  6G  4G BARNYARDGRASS0 0 0     0  9H  3C, 8H  3C, 8H  2C, 7G 0 0 0 0  4C, 9H 4G0 0 0 0  0 0  9H  5H     WILD OATS0 0 0 0  2C, 7G  5G  5G  0 0 0 0 0  7G 2G0 0 0 0  0 0  3C, 8H     6G ERA WHEAT0 0 0 0  3C, 9H  3C, 8H  5G  0 0 0 0 0  9H 7G0 0 0 0  0 0     9H  9H G4646 CORN0 0 0 0  2C, 6G  3G  0  0 0 0 0 0  2C, 7G 3G0 0 0 0  0     0  2G  2G WILLMS SOYBEANS0 0 0 0  3C, 9H  3C, 7H  3G  2H 0 0 0 0  9H 8G0     0 0 0  0 0  3C, 8H  3C, 6H RICE DRY SEEDED0 0 0 0 10E 10E 10E  9H 0 0 0     0  4C, 9H 3C, 8H0 0 0 0  0 0 10E 10E G522 SORGHUM0 0 0 0 10H  6C, 9H     7C, 9H  9H 0 0 0 0  9H 9H0 0 0 0  2C, 3G 0  9H  9H CHEAT GRASS -- ----     --  9G  9G  9H  6G 0 0 0 0  8G 2G0 0 0 0  0 0  8H  7H USH11 SUGARBEET0 0     0 0  5C, 9G  9G  4C, 8H  6H 2G 0 0 0 5G 5G0 0 0 0  8G 0  9G      9G VELVETLEAF0 0 0 0  3C, 8G  4G  0  0 0 0 0 0  3C, 8G 2G0 0 0 0  3G 0     3C, 8H  3C, 5H GIANT FOXTAIL0 0 0 0  9H  2C, 8G  3C, 5G  0 0 0 0 0  9H     2C, 9G0 0 0 0  2G 0  9H  9H KLAGES BARLEY0 0 0 0  8G  7G  7G  0 0 0 0 0     8G 2C, 2G0 0 0 0  0 0  9G      8G DOWNY BROME 0 0 0 0 -- --                    PRSOL CMPD 101 CMPD 102 C     MPD 103 CMPD 104 CMPD 105 CMPD 106 CMPD 107 CMPD 108 CMPD 109 CMPD 110     CMPD 111 CMPD 112 RATE = KG/HA 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01     0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01     0.05 0.01       COKER COTTON  5G 2C, 3G 2G 0 0 0 0 0 0 0  2G 0 0 0 0 0 0 0  1H 0 0 0     7G 2G CULT MORNINGLRY  8G 7H 1C 0 0 0 0 0 0 0  1C 00 0 0 0 0 0  3G 0 0 0      9G 3C, 4G COCKLEBUR -- 2C 1H 0 0 0 0 0 0 0  2G 00 0 0 0 0 0  2C 0 0 0     8H 8H PURPLE NUTSEDGE 10E 5G 0 0 -- 0 0 0 0 0 10E 00 0 0 0 0 0 10E 0 0 0     10E 10E LARGE CRABGRASS  2C, 5G 2C 0 00 0 0 0 0 0  3G 00 0 0 0 0 0  7G     4G 0 0  0 0 BARNYARDGRASS  9H 6G 0 00 0 0 0 0 0  7H 00 0 0 0 0 0  3C, 5G     3G 0 0  8H 7H WILD OATS  5G 0 0 00 0 0 0 0 0  2C, 3G 00 0 0 0 0 0  0 0 0     0  2G 0 ERA WHEAT  7G 0 0 00 0 0 0 0 0  6G 00 0 0 0 0 0  5G 0 0 0  3G 3G     G4646 CORN  2G 0 0 00 0 0 0 0 0  2C, 4G 00 0 0 0 0 0  3C, 7G 2C, 5G 0 0     9G 8G WILLMS SOYBEANS  4G 2H 2G 00 0 0 0 0 0  1C 00 0 0 0 0 0  1H 0 0 0     3C, 7G 1C, 1H RICE DRY SEEDED  9H 8H 0 00 0 0 0 0 0  8H 00 0 0 0 0 0  6G     2G 0 0  9H 8H G522 SORGHUM  9H 4C, 9H 0 00 0 0 0 0 0  2C, 8H 00 0 0 0 0     0 10H 3C, 3G 0 0  9H 7H CHEAT GRASS  8G 5G 0 00 0 0 0 0 0  4G 00 0 0 0 0     0  4G 0 0 0 -- -- USH11 SUGARBEET  9G 5G 5G 00 0 0 0 3H 0  2G 00 0 0 0 0     0  6G 4H 0 0  9G  2H VELVETLEAF  4G 0 2G 00 0 0 0 0 0  6G 00 0 0 0 3G 0     1H 0 0 0  7H  5H GIANT FOXTAIL  3C, 8H 5G 0 00 0 0 0 0 0  9H 00 0 0 0 0     0  2C, 8G 4G 0 0  4G 0 KLAGES BARLEY  9G 7G 0 00 0 0 0 0 0  5G 00 0 0 0     0 0  3C, 7G 2G 0 0  7G 2C, 3G DOWNY BROME                 -- -- -- -- --     --      9H 7G     PRSOL CMPD 113 CMPD 114 CMPD 115 CMPD 116 CMPD 117 CMPD 118 CMPD 119     CMPD 120 CMPD 121 RATE = KG/HA 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01     0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01       COKER COTTON  8G 4G 0 0 0 0  9G 8G  9G 2C, 6G  9G 9G  9G  8G  4C, 8G     5G  9G 2C, 6G CULT MORNINGLRY  2C, 2H 0 0 0 0 0  9G 9G  9G 9G  9G 9G  8G      8G  9G 2C, 5G  9G 9G COCKLEBUR  5H 1C 2G 0 2G 3G  9H 9H  8H 3C, 7H  8H     -- 10C  9H  8H 3C, 6H  9H 9H PURPLE NUTSEDGE  9G 0 0 0 0 0  9G 9G  5C,     9G 9G 10E 7G 10E 10E  5G 2G  7G 7G LARGE CRABGRASS  0 0 0 0 7G 0  5G 2G     2C, 7G 6G  7G 4G  3C, 9H  9G  4C, 9G 2C, 4G  4C, 8G 2C, 5G BARNYARDGRASS      8H 0 0 0 0 0  9H 4H  9H 2C, 5G  9H 2C, 7H  9H  3C, 8H  5C, 9H 2G  4C,     9H 3C, 7H WILD OATS  0 0 0 0 0 0  7G 2G  2C, 7G 2G  2G 0  3C, 8G  6G  5G     0  4C, 8G 2G ERA WHEAT  2G 0 0 0 0 0  4C, 9G 5G  3C, 9H 7G  2C, 8H 8G     5C, 9H  8G  7G 0  3C, 9H 4G G4646 CORN  2C, 7G 0 0 0 2C, 5G 0  3C, 9G     3C, 7G  9G 3C, 8H  9G 3C, 8G  9G  3C, 9H  2C, 9G 2C, 6G  9G 3C, 7H     WILLMS SOYBEANS  1C 0 0 0 0 0  4C, 8H 3C, 8G  4C, 9H 3C, 6G  2C, 9H 3C,     7H  9H  9H  9H 4C, 8H  9H 4C, 8H RICE DRY SEEDED  8G 6G 0 0 7G 0 10E 3C,     8G 10H 4C, 8H 10H 9H 10E 10H 10H 3C, 7H 10H 4C, 8H G522 SORGHUM  8G 8G 0     0 7G 0  9H 3C, 7G  3C, 9H 3C, 9H  9H 9H  5C, 9H  4C, 9H  4C, 8H 3C, 6H     3C, 9H 5C, 8H CHEAT GRASS -- -- -- -- -- --  4C, 8G 7G  3C, 8H 8G  8G 8G      9H  8H  3C, 8G 0  4C, 8H 3C, 8H USH11 SUGARBEET  8G 4H 3G 0 3G 0  5C,     9G 9G  4C, 9G 3C, 9G  4C, 9G 4C, 9G  5C, 9G  7G  5C, 9G 2C, 4G  5C, 9G     4C, 9G VELVETLEAF  3H 0 0 0 0 0  3C, 9G 9G  4C, 9G 4C, 9G  4C, 9G 3C, 7G      4C, 9G  3C, 9G  9C 2G  4C, 8G 3C, 3G GIANT FOXTAIL  0 0 0 0 5G 0  3C,     7H 2H  9H 3C, 8H  8G 3C, 7H  9H  8G  7G 0  9H  7G KLAGES BARLEY  2C, 5G     0 0 0 7G 0  2C, 9G 2C, 6G  8G 6G  8G 8G  9G  9G  2C, 8G 5G  9H 7G DOWNY     BROME 10C 3G 0 0 5G 0 -- --      9G 7G                                 POSOL CMPD 1 CMPD 2 CMPD 3 CMPD 4 C     MPD 5 CMPD 6 CMPD 7 CMPD 8 CMPD 9 CMPD 10 RATE = KG/HA 0.05 0.01 0.05     0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05     0.01 0.05 0.01       COKER COTTON  9C  4C, 9H 0 0 2G 0 0 0 0 0 0 0 0 0  4C, 9H  2C, 5G  3C,     9G 9H 3C, 8H 2C, 3G CULT MORNINGLRY 10C 10C 1H 0 9C 4C, 8G 1H 0 0 0 0 0     0 0 10C  4C, 9G  9C 5C, 9G 4C, 9H 3C, 5H COCKLEBUR 10C  9C 1H 0 5C, 9G     3C, 8G 2H, 5G 0 2G 0 0 0 0 0 10C 10C 10C 9C 4C, 9H 3C, 7H PURPLE     NUTSEDGE  9C  4C, 9G 0 0 3C, 8G 2C 0 0 0 0 0 0 0 0  6C, 9G  2C, 9G  4C,     8G 2C, 5G 2C, 4G 0 LARGE CRABGRASS  2C, 8G  5G 0 0 0 0 0 0 2G 0 0 0 0 0     2G 0  3G 0 0 0 BARNYARDGRASS  9C  9C 2H 0 3C, 8H 3C, 7H 1H 0 4C, 8H 0 0     0 0 0  9C  4C, 9H  3C, 9H 3C, 7H 3C, 6H 5H WILD OATS  4C, 9G  9G 0 0 3C,     8G 0 0 0 9G 0 0 0 0 0  9G  9G  3C, 9G 8G 2C, 6G 0 ERA WHEAT  9C  4C, 9G     2G 0 6G 0 2G 0 9G 0 0 0 0 0  2C, 9G  9G  9C 7G 4G 0 G4646 CORN  2H  0 0     0 0 0 0 0 3C, 9G 0 0 0 0 0  4C, 9G  3C, 7H  3C, 8H 1H 0 0 WILLMS     SOYBEANS  4C, 9H  2C, 4G 0 0 1C 0 0 0 0 0 0 0 0 0  4C, 9G  2C, 7H  4C,     8H 3H 1C, 1H 0 RICE DRY SEEDED  6C, 9G  9C 0 0 9C 5G 2G 0 8G 0 0 0 0 0     9C  9C  9C 5C, 9G 9G 5G G522 SORGHUM  9C  9C 3G 0 9C 9C 2C, 5G 2C, 2G     3C, 8H 0 0 0 0 0  9C  9C  5C, 9G 4C, 9G 4C, 9G 4C, 9G CHEAT GRASS 10C     9C 2G 0 5C, 9G 7G 0 0 3C, 8G 0 0 0 0 0  9C  4C, 8G  4C, 9G 3C, 7G 8G 3G     USH11 SUGARBEET  9C  9C 0 0 9C 3C, 7H 0 0 3C, 7G 0 0 0 0 0 10C  9C  9C     4C, 8G 3C, 8H 6G VELVETLEAF 10C  5C, 9G 0 0 7G 0 0 0 0 0 0 0 0 0 10C     4C, 9H  9C 4C, 9H 2C, 3G 0 GIANT FOXTAIL  9C  6C, 9G 2G 0 2C, 4G 2G 0 0     2C, 5G 0 0 0 0 0  4C, 9G  4C, 8G  3C, 5G 2G 1C 0 KLAGES BARLEY  5C, 9G     2C, 8G 0 0 2C, 6G 0 0 0 3C, 7G 0 0 0 0 0  9G  7G      2C, 8G 4G 0 0            POSOL CMPD 11 CMPD 12 CMPD 13 CMPD 14 CMPD 15     CMPD 16 CMPD 17 CMPD 18 CMPD 19 CMPD 20 RATE = KG/HA 0.05 0.01 0.05 0.01 0     .05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01     0.05 0.01       COKER COTTON 3C, 8H 2G 0 0 0 0 0 0 10C  3C, 9H  3C, 9H 3C, 8H 4C, 8H 0     3C, 8H 2C 0 0 0 0 CULT MORNINGLRY 3C, 7H 2C, 2H 0 0 1C, 3G 0 0 0 10C 10C      6C, 9G 6C, 9H 5C, 9G 2C, 7H 4C, 8H 3G 0 0 0 0 COCKLEBUR 3C, 9H 2C, 3H     4C, 8H 2H 3C, 9G 3H 2C, 5G 0 10C 10C  9C 4C, 9H 4C, 8H 1H 3C, 8H 3C, 5G     2H 0 2H 0 PURPLE NUTSEDGE 0 0 0 0 0 0 0 0  4C, 9G  9G  9G 6G 3C, 5G 0 2G     2G 0 0 0 0 LARGE CRABGRASS 0 0 0 0 0 0 0 0  9G  2C, 5G  7G 2G 0 0 2G 0 0     0 0 0 BARNYARDGRASS 5H 3H 2H 0 5H 0 7H 0 10C 10C  9C 3C, 9H 5C, 9H 3C,     7H 3C, 8H 3C, 6H 0 0 2G 0 WILD OATS 2C, 8G 5G 2G 0 0 0 7G 0  3C, 9G  3C,     9G 4C, 9G 3C, 8G 9G 4G 2C, 9G 9G 2G 0 0 0 ERA WHEAT 7G 5G 3G 0 6G 0 8G     2G  4C, 9G  8G  9G 9G 7G 3G 9G 8G 5G 0 3G 0 G4646 CORN 0 0 5H 0 3H 0 6H     0  3C, 8H  2G  3G 2G 0 0 1H 0 0 0 0 0 WILLMS SOYBEANS 0 0 0 0 0 0 0 0     9C  3C, 8G  5C, 9G 4C, 9G 3C, 6H 2G 3C, 8G 3C, 3H 2C, 2H 0 3C 0 RICE DRY     SEEDED 3C, 5G 2C, 5G 2G 0 2G 0 2C, 5G 0  9C  9C  9C 9C 5C, 9H 2G 5C, 9G     5C, 9G 0 0 0 0 G522 SORGHUM 9C 3C, 7H 2C, 5G 0 8G 0 3C, 8H 0 10C  9C     3C, 9G 3C, 9G 5C, 9G 4C, 9G 3C, 9G 4C, 9G 0 0 3C, 3G 0 CHEAT GRASS 5G 3G     3G 0 7G 0 2C, 8G 0 10C      9C 10C 4C, 9G 9G 9G 9C 9G 0 0 0 0 USH11 SUGARBEET 4C, 8G 3C, 3H 2H 0 3H     0 3H 0  9C  9C      9C 4C, 9H 4C,8H 3C, 6G 3C, 7H 3C, 5G 1C 0 2H 0 VELVETLEAF 3C, 7H 2C, 5G     0 0 0 0 0 0 10C  5C, 9H 10C 5C, 9H 4C, 8H 5G 3C, 7G 3C, 6G 3G 0 0 0     GIANT FOXTAIL 0 0 0 0 0 0 2G 0 10C  9C  9C 3C, 9G 9C 3C, 7G 3C, 9G 3C,     6G 2G 0 0 0 KLAGES BARLEY 3G 0 2G 0 0 0 2C, 8G 4G  9C  3C, 8G  2C, 8G 6G     4G 0 2C, 8G 6G 2G 0 0 0       POSOL CMPD 21 CMPD 22 CMPD 23 CMPD 24 CMPD 25 CMPD 26 CMPD 27 CMPD 28     CMPD 29 CMPD 30 RATE = KG/HA 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01     0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01       COKER COTTON 10C  9C 2C, 5G 0 10C 2C, 6G 2G 0 0 0 0 0  5C, 9G 4C, 8G     3C, 9G 4C, 9G 4C, 8H 3G 0 0 CULT MORNINGLRY 10C 10C 2C, 7G 0 10C 4C, 9G     2C, 5H 0 0 0 2C 0  5C, 9G 2C, 7G 10C 5C, 9H 4C, 9G 3C, 7H 3C, 6G 0     COCKLEBUR 10C 10C 5G 0 10C 7H 4G 0 1H 0 0 0 10C 2C, 8G 10C 4C, 9H 4C, 9H     2C, 6H 2H 0 PURPLE NUTSEDGE 10C 9G 0 0  3C, 8G 7G 0 0 0 0 0 0  0 0  2C,     9G 9G 2C, 8G 5G 0 0 LARGE CRABGRASS  5C, 9G  8G 3G 0  7G 2G 2G 0 0 0 0 0      0 0  4C, 9G 2C, 8G 3C, 7G 2C, 5G 2C, 4G 0 BARNYARDGRASS  9C  9C 2C, 5H     2G  9C 5C, 9H 2C, 5G 0 3G 0 0 0  3C, 7G 4G  9C 9C 9C 4C, 8H 4C, 9H 3C,     6H WILD OATS  3C, 9G  3C, 9G 0 0  8G 6G 2G 0 8G 0 0 0  3C, 6G 0  6C, 9G     9G 4C, 9G 2C, 9G 9G 3G ERA WHEAT  5C, 9G 10C 0 0  8G 4G 6G 0 9G 0 3G 0     4C, 9G 0  6C, 9G 9G 4C, 9G 2C, 9G 7G 4G G4646 CORN  1C, 4H  2G 0 0  0 0     0 0 3G 0 0 0  2H 0  2U, 9G 9G 2C, 9G 2C, 5H 2C, 5G 0 WILLMS SOYBEANS  9C      5C, 9G 3C, 4H 1C, 1H  3C, 8H 3C, 4G 3C, 5H 1H 2C, 2H 0 0 0  4C, 9G 3C,     8G  9C 9C 5C, 9G 4C, 8H 3C, 3H 1C RICE DRY SEEDED  9C  9C 3G 0  3C 5C,     9G 3G 0 4G 0 0 0  5G 2G  9C 9C 9C 5C, 9G 8G 0 G522 SORGHUM  9C  9C 3C,     8G 3G  9C 9C 3C, 7G 2G 2G 0 0 0  4C, 9G 3C, 8G  9C 5C, 9G 4C, 9G 3C, 7G     3C, 8H 3C, 3H CHEAT GRASS  9C  9C 5G 0  5C, 9G 9G 3G 0 8G 0 2G 0  7G 3G     9C 9C 5C, 9G 4C, 9G 3C, 9G 7G USH11 SUGARBEET 10C 10C 2C, 5G 2G  9C 5C,     9G 3G 2G 2H 0 0 0  6C, 9G 3C, 6G      9C 9C 5C, 9G 2C, 4G 3C, 4H 2C VELVETLEAF 10C 10C 2G 0  9C 8G 3C, 7G 3H     0 0 2G 0  6C, 9G 3C, 7G  9C 4C, 8H 4C, 9H 3C, 6H 5G 0 GIANT FOXTAIL 10C     10C 6G 0 10C 4C, 9G 2C, 7G 5G 0 0 2G 0  4C, 8G 5G  9C 9C   5C, 9G 3C, 7G     4C, 9G 2C, 5G KLAGES BARLEY  5C, 9G  4C, 9G 0 0  3C, 9G 3G 0 0 7G 0 0 0     2G 0      5C, 9G 4C, 9G 4C, 9G 3C, 7G 2C, 5G 3G     POSOL CMPD 31 CMPD 32 CMPD 33 CMPD 34 CMPD 35 CMPD 36 CMPD 37 CMPD 38     CMPD 39 CMPD 40 CMPD 41 RATE = KG/HA 0.05 0.01 0.05 0.01 0.05 0.01 0.05     0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05     0.01       COKER COTTON 1H 0 0 0 2C, 4H 0  9C  4C, 8G 0 0 6G 2G 0 0 0 0 0 0  4C,     9G 9H 3C, 9G 3C, 8H CULT MORNINGLRY 0 0 0 0 2C 0  6C, 9G  4C, 9G 3G 0     5C, 9H 3C, 7H0 0 0 0 0 0 10C 4C, 8H 9C 3C, 8H COCKLEBUR 0 0 0 0 1C 0 10C      4C, 9H 2C, 4G 0 4C, 9H 4C, 6H0 0 0 0 0 0 10C 4C, 9G 9C 3C, 9G PURPLE     NUTSEDGE 0 0 0 0 0 0  3C, 9G  2C, 9G 0 0 3G 00 0 0 0 0 0  9G 8G 3G 0     LARGE CRABGRASS 2G 0 0 0 0 0  5C, 9G  9G 0 0 2C, 8G 5G0 0 0 0 0 0  3G 0     0 0 BARNYARDGRASS 3C, 8H 2H 0 0 0 0  9C  4C, 9G 2C, 8H 0 9C 2C, 8H0 0 0     0 0 0  9C 3C, 9H 4C, 9G 4C, 8H WILD OATS 2C, 9G 4G 0 0 0 0  2C, 9G  9G     8G 0 9G 3G0 0 0 0 0 0  3C, 9G 8G 3C, 9G 3C, 8G ERA WHEAT 8G 4G 0 0 0 0     4C, 9G  2C, 9G 9G 0 9G 00 0 0 0 0 0  9G 8G 9G 9G G4646 CORN 2C, 7H 1H 2G     0 0 0  4C, 9G  2C, 8G 0 0 0 00 0 0 0 0 0  4C, 9H 2G 7G 0 WILLMS SOYBEANS     3C, 5H 1C, 1H 0 0 2C, 5H 0  9C  5C, 9G 1C, 5H 2C 4C, 8G 2C, 4H 2H 0 0 0     0 0  4C, 9G 4C, 9G 4C, 7G 3C, 3H RICE DRY SEEDED 4C, 9G 2C, 2G 0 0 1C 0     5C, 9G  4C, 9G 7G 0 4C, 9G 2C, 6G 0 0 0 0 0 0  5C, 9G 5C, 9G 5C, 9G 3C,     7G G522 SORGHUM 3C, 8H 0 0 0 0 0  9C  6C, 9G 2G 0 3C, 9G 3C, 9G0 0 0 0 0     0  4C, 9G 4C, 9G 4C, 9G 4C, 9G CHEAT GRASS 4C, 9G 7G 0 0 0 0  9C  4C, 9G     8G 4G 3C, 9G 9G 0 0 0 0 0 0  9C 6G 5C, 9G 4C, 8G USH11 SUGARBEET 2C, 2H     0 0 0 2C 0  4C, 9H  2C, 6H 2G 0 4C, 8H 2C, 7G 0 0 0 0 0 0  9C 9C 4C, 8H     3C, 7G VELVETLEAF 2C, 5H 0 0 0 1C 0 10C 10C5G 0 7G 00 0 0 0 4G 0  4C, 9H     4C, 7H 3C, 8H 3C, 6H GIANT FOXTAIL 2G 0 0 0 0 0  9C  9C 7G 0 4C, 9G 3C,     9G0 0 0 0 0 0  4C, 9G  3C, 7G 3C, 7G 3G KLAGES BARLEY 3C, 7G 3G 0 0 0 0     4C, 9G  3C, 8G 4G 0 3C, 8G 2C, 7G 0 0 0 0 0 0      8G 7G 8G 5G                 POSOL CMPD 42 CMPD 43 CMPD 44 CMPD 45 CMPD     46 CMPD 47 CMPD 48 CMPD 49 CMPD 50 CMPD 51CMPD 52 RATE = KG/HA 0.05 0.01 0     .05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01     0.05 0.01 0.05 0.01 0.05 0.01       COKER COTTON 3C, 5H 0 2C, 3G 0 0 0 0 0  3C, 8G 3C, 7H 0 0 0 0 0 0 0 0     2G 0 3C, 5H 3G CULT MORNINGLRY 3C, 3H 0 3C, 6G 1H 0 0 0 0 10C 9C 2G 0     3C, 8H 3C, 6H 2H 0 0 0 2C, 7H 0 2C, 6H 2C, 2H COCKLEBUR 3C, 6H 2C, 2H     3C, 6G 1C, 1H 2C, 2H 1H 2C, 2H 0  3C, 9H 2C, 8G 0 0 3C, 8H 2C 0 0 0 0     2C, 6H 0 1C, 4G 0 PURPLE NUTSEDGE 0 0 0 0 0 0 0 0  9G 2C, 9G 0 0 5G 3G 0     0 0 -- 0 -- 0 0 LARGE CRABGRASS 0 0 2G 0 0 0 0 0  6G 4G 0 0 0 0 2G 0 0 0     3G 0 2G 0 BARNYARDGRASS 3C, 4G 0 3C, 7G 1H 0 0 0 0  9C 9C 2G 0 7H 4H 2G     0 2G 0 4G 0 4G 2G WILD OATS 5G 0 9G 2G 0 0 0 0  8G 2G 0 0 0 0 0 0 4G 0     2G 0 0 0 ERA WHEAT 2G 0 9G 2G 0 0 0 0  8G 8G 0 0 0 0 0 0 7G 0 4G 0 0 0     G4646 CORN 0 0 0 0 0 0 0 0  3G 0 0 0 0 0 0 0 0 0 0 0 0 0 WILLMS SOYBEANS     0 0 1C 0 0 0 0 0  4C, 9G 3C, 7H 0 0 0 0 0 0 0 0 0 0 0 0 RICE DRY SEEDED     3G 0 4C, 9G 0 0 0 0 0  9C 4C, 9G 0 0 2C, 7G 2G 0 0 2C 0 1C 0 2C, 2G 0     G522 SORGHUM 3C, 9G 0 4C, 8H 4G 0 0 0 0  4C, 9G 4C, 9G 4G 0 3C, 9G 3C,     7H 0 0 3G 0 3G 0 4H 0 CHEAT GRASS 6G 0 3C, 9G 8G 0 0 0 0  5C, 8G 5G 4G 0     5G 3G 0 0 4G 0 2G 0 2G 0 USH11 SUGARBEET 3C, 6H 0 3C, 6G 0 0 0 0 0  6C,     8G 3C, 7G 3H 0 2C, 4G 1H 0 0 1H 0 0 0 2C, 5G 0 VELVETLEAF 0 0 2C, 2G 0 0     0 0 0  4C, 9H 2C, 7H 0 0 -- 0 0 0 0 0 2G 0 6G 5G GIANT FOXTAIL 0 0 3C,     7G 4G 0 0 0 0  4C, 9G 2C, 8G 0 0 0 0 2C, 7G 0 0 0 3G 0 5G 2G KLAGES     BARLEY 0 0 7G 4G 0 0 0 0      9C 7G 2G 0 4G 0 0 0 5G 0 3G 0 0 0                POSOL CMPD 53 CMPD 54     CMPD 55 CMPD 56 CMPD 57 CMPD 58 CMPD 59 CMPD 60 CMPD 61 CMPD 62 CMPD 63     RATE = KG/HA 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0     .05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01       COKER COTTON 5G 0 0 0 0 0 0 0 0 0 0 0 0 0  9C  3C, 9G 4G 2G 2G 0 3C,     8H 3C, 6G CULT MORNINGLRY 3C, 7G 3C, 5H 0 0 3H 0 0 00 0 0 0 0 0 10C  3C,     9G 1H 0 0 0 3C, 7G 3C, 3H COCKLEBUR 3C, 5G 3G 0 0 1H 0 0 00 0 0 0 0 0     10C  9C 2H 0 0 0 3C, 7G 2C, 2H PURPLE NUTSEDGE 3C, 8G -- 0 0 0 0 0 00 0     0 0 -- 0  4C, 9G  8G 3G 0 0 0 2G -- LARGE CRABGRASS 0 0 0 0 0 0 0 00 0 0     0 0 0  4C, 7G  2G 0 0 0 0 0 0 BARNYARDGRASS 3C, 8H 4H 0 00 0 0 00 0 0 0     0 0 10C  9C 0 0 0 0 3G 0 WILD OATS 2C, 9G 0 0 00 0 0 00 0 0 0 0 0  5C,     9G  7G0 0 0 0 0 0 ERA WHEAT 7G 0 0 00 0 0 00 0 0 0 0 0  9C  9G 0 0 0 0 0     0 G4646 CORN 0 0 0 00 0 0 00 0 0 0 0 0  3C, 7H  0 1C, 4H 0 0 0 0 0     WILLMS SOYBEANS 0 0 0 00 0 0 00 0 0 0 0 0  5C, 9G  5C, 9G 2C, 8G 0 3H 0     3C, 7G 2C, 3H RICE DRY SEEDED 9G 5G 0 00 0 0 00 0 0 0 0 0  9C  9C 4G 0     2G 0 6G 0 G522 SORGHUM 3C, 9H 7G 0 00 0 0 00 0 0 0 0 0  9C  5C, 9G 2G 0     0 0 7G 0 CHEAT GRASS 9G 0 0 00 0 0 00 0 0 0 0 0  9C  4C, 9G 0 0 0 0 0 0     USH11 SUGARBEET 3C, 7G 4H 0 02H 0 0 00 0 0 0 0 0 10C  4C, 8G 5C, 9G 3C,     7G 3C, 7H 0 3C, 8H 3C, 8G VELVETLEAF 2C, 5G 0 0 0 0 0 0 00 0 0 0 0 0 10C     10C 3C, 7G 3G 3G 0 3C, 7G 3G GIANT FOXTAIL 2C, 5G 3G 0 00 0 0 00 0 0 0 0     0  4C, 9G  7G 0 0 0 0 0 0 KLAGES BARLEY 7G 0 0 00 0 0 00 0 0 0 0 0  5C,     9G      6G 0 0 0 0 0 0     POSOL CMPD 64 CMPD 65 CMPD 66 CMPD 67 CMPD 68 CMPD 69 CMPD 70 CMPD 71     RATE = KG/HA 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0     .05 0.01 0.05 0.01       COKER COTTON  5C, 9G  9C  9C  9C  9C  4C, 8G 10C 9C  9C 4C, 9G 3C, 5G     3C, 4G  9C  9C  9C  9C CULT MORNINGLRY 10C 10C 10C 10C 10C 10C 10C 4C,     9G 10C 4C, 9H 3C, 6G 3G 10C 10C  9C 10C COCKLEBUR 10C 10C  9C 10C 10C     10C 10C 9C 10C 8G 3G 2G 10C 10C 10C 10C PURPLE NUTSEDGE  5C, 9G  5C, 9G     9C  5C, 9G  5C, 9G  3C, 7G  5C, 9G 3C, 9G  5C, 9G 3C, 9G 5G 0 10C  9C     9C  9G LARGE CRABGRASS  6G  4G  6C, 9G  4C, 9G  9C   3C, 8G  5C, 9G 8G     6C, 9G 4C, 8G 6G 4G  5C, 9G  4G  8G  5G BARNYARDGRASS  9C  3C, 9H  9C     9C  9C  9C  9C 9C  9C 9C 9C 2C, 2H  9C  9C  9C  9C WILD OATS  8G  2C, 3G     10C  9C  9C  5C, 9G  6C, 9G 9G  9C 9C 5C, 9G 1C  5C, 9G  9G  4C, 9G  9G     ERA WHEAT  7G  5G  6C, 9G  6C, 9G  9C  9G  9G 5G  4C, 9G 5C, 9G 5C, 9G     8G  9G  7G  4C, 9G  8G G4646 CORN  3C, 6G  3G  7U, 9C  7U, 9C  6U, 9G     3U, 9G  5U, 9G 9H  2C, 9G 3C,7G 4U, 9G 9G  9C  9C  3C, 9G  3C, 8H WILLMS     SOYBEANS  5C, 9G  9C  9C  9C  9C  5C, 9G  5C, 9G 5C, 9G  5C, 9H 9C 4C,     8H 2C, 5G  9C  9C  9C   9C RICE DRY SEEDED  9C  5C, 9G  9C  9C  9C  9C     5C, 9G 9C  9C 9C 9C 5C, 9G  9C  9C  9C  3C, 8G G522 SORGHUM  3C, 9G  4C,     9G  9C  9C  5C, 9G  4C, 9G  9C 9C  9C 6C, 9G 3C, 7G 3C, 3G  9C  9C  9C     9G CHEAT GRASS  3C, 8G  4C, 9G  9C  9C  9C  9C  9C 9C  9C 6C, 9G 5C, 9G     9G 10C  5C, 9G  9C  4C, 9G USH11 SUGARBEET  9G  3C, 8G  9C  9C 10C 10C     9C 9C 10C 9C 3C, 5G 5H  9C  9C 10C  9C VELVETLEAF  9C  5C, 9G  9C  9C     10C  9C 10C 3C, 9G 10C 4C, 9H 2H 3G 10C 10C  9C  9C GIANT FOXTAIL  7G     3G  9C 10C  9C  9C  6C, 9G 8G 10C 5C, 9G 3C, 9G 2G 10C  9C  9C  3C, 8G     KLAGES BARLEY  3C, 7G   2C, 6G  9C  6C, 9G  6C, 9G  4C, 9G  3C, 8G 5G     6C, 9G 5C, 9G 5C, 9G 3C, 6G  3C, 9G  6G  4C, 9G      7G                        POSOL CMPD 72 CMPD 73 CMPD 74 CMPD 75 CMPD 76 C     MPD 77 CMPD 78 CMPD 79 CMPD 80 CMPD 81 RATE = KG/HA 0.05 0.01 0.05 0.01     0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01     0.05 0.01       COKER COTTON  9C  9C  5C, 9G  3C, 8G 2C, 5G 1C 3C, 5G 2C, 5G 0 0 0 0 0     0 0 0 0 0  4C, 9G  0 CULT MORNINGLRY 10C 10C 10C  9C 3C, 8H 2C, 3H 3C,     7H 1C, 1H 0 0 0 0 0 00 0 0 0  4C, 9G  3C, 6G COCKLEBUR 10C 10C 10C 10C     3C, 5H 1H 2C, 6H 9C 2H 0 0 0 0 00 0 0 0 10C 10C PURPLE NUTSEDGE --  3C,     9G  4C, 9G  4C,8G 5G 0 3G 0 0 0 -- 0 0 0 -- 0 0 0 --  5C, 9G LARGE     CRABGRASS  2C, 7G --  5C, 9G  3C, 7G 7G 2G 3C, 7G 3G 0 0 0 0 0 0 1C, 3G     0 0 0  3C, 8G -- BARNYARDGRASS  9C  9C 10C  9C 9C 3C, 7H 9C 9C 0 00 0 0     00 0 0 0 10C  3C, 9H WILD OATS  9G  8G  5C, 9G  3C, 9G 5C, 9G 4C, 9G 9C     9C 0 00 0 0 00 0 0 0  2C, 5G  0 ERA WHEAT  9G  5G  2C, 9G  9G 9G 6G 2C,     9G 2C, 9G 0 00 0 0 00 0 0 0  2G  0 G4646 CORN  3C, 9H  2C, 7G  3C, 9H     2C, 5G 5C, 9G 2C, 9G 5C, 9G 5C, 9G 0 00 0 0 00 0 0 0  9C  9G WILLMS     SOYBEANS  9C  3C, 8H  9C  9C 4C, 8H 5G 4C, 9G 7H 0 00 0 0 00 0 0 0  3C,     8G  4G RICE DRY SEEDED  9C  8G  9C  9C 9C 9C 9C 9C 0 00 0 0 00 0 0 0  9C      5C, 9G G522 SORGHUM  9C  9C  9C  9C 5C, 9G 4C, 9G 9C 5C, 9G 0 00 0 0 00     0 0 0  9C  4C, 9G CHEAT GRASS  9C  9G  9C  5C, 9G 4C, 9G 9G 5C, 9G 3C,     9G 0 00 0 0 00 0 0 0  2C, 6G  2G USH11 SUGARBEET 10C  9C 10C  9C 4C, 9H     3C, 6H 3C, 6G 5C, 9G 0 00 0 0 0 2C, 6G 3G  0 10C  9C VELVETLEAF  9C  8G     4C, 9G  8G 3C, 6H 0 0 7G 0 00 0 0 0 0 0 3G 0 10C  9C GIANT FOXTAIL  4C,     9G  2C, 7G  9C  2C, 9G 9C 3C, 7G 9C 3C, 8G 0 00 0 0 0 3G 0 0 0  9C  4C,     8G KLAGES BARLEY  2C, 9G  4G  3C, 9G  7G 9C 9G 9C 9C 0 00 0 0 0 0 0 0 0     8G      7G     POSOL CMPD 82 CMPD 83 CMPD 84 CMPD 85 CMPD 86 CMPD 87 CMPD 88 CMPD 89     CMPD 90 CMPD 91 RATE = KG/HA 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01     0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01       COKER COTTON  2G 0 0 0 0 0 0 0  9C  4G 0 0 0 0  1H 0 0 0 0 0 CULT     MORNINGLRY  2G 0 2C, 2G 0 3C, 7G 0 3C, 4H 0  4C, 8G  3C, 3G 0 0 0 0  3C,     4G 0 0 00 0 COCKLEBUR  5C, 9G 4C, 9G 5C, 9G 3C, 8H 4C, 9H 2H 4C, 9H 2H     5C, 9G  1C 0 0 0 0  3C, 6G 2G 0 00 0 PURPLE NUTSEDGE 10C -- 5G 0 0 0 --     0 10C 10C -- 0 0 0  0 0 0 00 0 LARGE CRABGRASS  5G 0 5G 0 3C, 7G 0 5G --      9C  3C, 6G 0 0 0 0  0 0 0 00 0 BARNYARDGRASS  3C, 8H 2C, 5G 3C, 8H 3G     4C, 9G 3C, 6G 9C 3C, 8G  9C  3C, 8H 0 0 0 0  4C, 9H 2G 0 00 0 WILD OATS     2G 0 2C, 6G 0 0 0 0 0  3C, 5G  0 0 0 0 0  2C, 5G 0 0 00 0 ERA WHEAT  2G     0 0 0 0 0 0 0  3C, 5G  2G0 0 0 0  3C, 5G 0 0 00 0 G4646 CORN  3C, 9H 3G     3C, 7H 0 4C, 9G 4C, 8G 5C, 9G 9G  4C, 9G  3C, 7G 2G 0 0 0  3C, 8H 0 0 00     0 WILLMS SOYBEANS  1H 0 0 0 3C, 3H 0 3G 0  9C  4C, 9G 0 0 0 0  3C, 7G 1H     3H 00 0 RICE DRY SEEDED  3C, 8G 8G 9C 7G 5C, 9G 8G 9C 3C, 8G  9C  3C, 8G     0 0 0 0  6G 0 0 00 0 G522 SORGHUM  5C, 9H 2C, 8G 4C, 9G 2C, 8G 5C, 9G     3C, 8G 5C, 9G 3C, 9G  3C, 9G  3C, 7G 2C, 6G 0 0 0  3C, 9H 2C, 4G 0 00 0     CHEAT GRASS  2C, 5G 0 4G 0 0 0 0 0 -- -- -- -- -- -- -- -- -- -- -- --     USH11 SUGARBEET  9C 2C, 4H 3C, 5H 4G 2H 0 3C, 6G 2H 10C 10C 3G 0 0 0 10C     4G 3G 00 0 VELVETLEAF  5G 0 -- 0 -- 0 3C, 7G 0  9C 10C0 0 0 0  3C, 6G 0     0 00 0 GIANT FOXTAIL  0 0 2C, 5G 0 4C, 9G 3C, 8G 5C, 9G 3C, 7G  9C  2G0     0 0 0  2C, 5G 0 0 00 0 KLAGES BARLEY  4G 0 2C, 5G0 0 0 3G 0  2C, 5G  00     0 0 0  3C, 8G 0 0 00 0 DOWNY BROME       -- --  5C, 9G  5C, 9G0 0 0 0     4C, 7G 0 0 00 0       POSOL CMPD 92 CMPD 93 CMPD 94 CMPD 95 CMPD 96 CMPD 97 CMPD 98 CMPD 99     CMPD 100 CMPD 101 RATE = KG/HA 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01     0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01       COKER COTTON 10C 10C  6C, 9G 4C, 9G 2C, 5G 2G 0 0  4C, 8G  5G 0 0 0 0     4C, 9G 3C, 9H  5C, 9G 5C, 9G 5C, 9G 3C, 6H CULT MORNINGLRY 10C 10C  9C     4C, 9G 1H 0 2C 0 10C 10C 2C, 7G 0 2G 0   3C, 8G 2C, 5H  9C 9C 5C, 9G 3C,     8H COCKLEBUR 10C 10C 10C 3C, 8H 2G 0 0 0 10C  4C, 9H 2C 0 0 0  4C, 9H     3C, 8H 10C 9C 9G 2C, 8H PURPLE NUTSEDGE  9C  5C, 9G  2C, 9G 2C, 6G 0 0 0     0  9G  2C, 5G 5G 0 4G 0  0 0  4C, 9G 2C, 9G 9G 4G LARGE CRABGRASS  8G     5G  5G 0 0 0 0 0 10C  9G 0 0 0 0  0 0      3C, 7G 3C, 7G 2C, 4G 0 BARNYARDGRASS  9C  9C  3C, 9H 3C, 7H 1H 0 0 0     10C  9C 0 0 0 0  0 0  9C 9C 3C, 9H 2C, 6G WILD OATS  5C, 9G  3C, 8G  5G     3G 0 0 0 0  3C, 9G  9G 0 0 0 0  0 0  5C, 9G 3C, 9G 2C, 7G 1C ERA WHEAT     6C, 9G  9G  8G 3G 0 0 0 0  3C, 9G  9G 2G 0 0 0  0 0  9G 9G 2C, 5G 3G     G4646 CORN  6G  3G  3G 0 0 0 0 0  3C, 9H  5G 0 0 0 0  2C, 6G 0  3C, 9H     1C 0 0 WILLMS SOYBEANS  9C  9C  3C, 7G 2C, 6H 3C, 4H 2H 0 0  5C, 9H  6C,     9G 2H 0 0 0  4C, 8H 3C, 6H  5C, 9G 4C, 9H 3C, 7G 0 RICE DRY SEEDED  9C     6C, 9G  6C, 9G 5C, 9G 0 0 0 0  5C, 9G  5C, 9G 0 0 0 0  2G 0  9C 9C 4C,     9G 2C, 8G G522 SORGHUM  9C  5C, 9G  9C 9C 2G 0 0 0  9C  3C, 9G 4G 0 0 0     3C, 7H 6G  9C 9C 5C, 9G 4C, 9G CHEAT GRASS  9C  9C  2C, 9G 8G 0 0 0 0     9C  9G 0 0 0 0  5G 0  9C 9G 3C, 9G 2C, 9G USH11 SUGARBEET  9C  9C  9C 9C     0 0 0 0 10C  3C, 7G 8G 4G 7G 0 10C 6H  9C 9C 5C, 9H 5C, 9H VELVETLEAF     10C 10C  4C, 9H 5H 2C, 7G 0 0 0 10C  9G 0 0 3G 0  9G 7G  9C 9C 3C, 7H 1H     GIANT FOXTAIL  9C  9C  3C, 8G 3C, 6G 2G 0 0 0 10C  5C, 9G 0 0 2C 0  0 0     9C 5C, 9G 3C, 7G 2C KLAGES BARLEY  5C, 9G  2C, 8G  2C, 5G 0 0 0 0 0  6C,     9G  8G 0 0 0 0  0 0      5C, 9G 4C, 9G 2C, 5G 3G DOWNY BROME -- --             POSOL CMPD 102     CMPD 103 CMPD 104 CMPD 105 CMPD 106 CMPD 107 CMPD 108 CMPD 109 CMPD 110     CMPD 111 CMPD 112 RATE = KG/HA 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01     0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01  0.05 0.01 0.05     0.01     COKER COTTON 3C, 3H 0 0 0 0 0 3C, 9H 3C, 7H 3C, 6G 2C, 4G 0 0     2G 0 0 0  4C, 9G 4C, 8H 0 0  4C, 8H  3C, 8H CULT MORNINGLRY 2C, 3H 1H 0     0 0 0 2C, 4H 2G 9C 3C, 8H 0 0 2C, 4G 0 1C 0  6C, 9G 3C, 8G 0 0 10C 10C     COCKLEBUR 2H 2G 3G 0 0 0 3C, 9H 3C, 9H 5C, 9G 2C, 8H 0 0 1C 0 0 0  5C,     9G 3C, 9G 0 0 10C 10C PURPLE NUTSEDGE 0 -- 4G 0 -- 0 0 -- 2C, 7G 2C, 2G     0 0 0 0 0 0  4G 3G 0 0  9C  5C, 9G LARGE CRABGRASS 4G 0 0 0 0 0 0 0 0 0     0 0 2G 0 2G 0  9C 2G 0 0  0  0 BARNYARDGRASS 2H 00 0 0 0 0 0 9C 5C, 9G 0     0 4G 0 0 0  9C 3C, 8H 0 0  9C -- WILD OATS 2C, 8G 00 0 0 0 0 0 9C 9C 0 0     3G 0 0 0  2C, 7G 4G 0 0  4C, 9G  3G ERA WHEAT 2C, 8G 3G0 0 0 0 0 0 9G 9G     0 0 2G 0 0 0  3C, 9G 5G 0 0  3C, 8G  3G G4646 CORN 0 00 0 0 0 0 0 2C, 2G     2C 0 0 0 0 0 0  3C, 8H 2C, 4G 0 0  5U, 9C  3C, 9G WILLMS SOYBEANS 3C, 4H     00 0 0 0 2C, 6H 4H 3C, 9G 0 0 0 0 0 0 0  3C, 7H 2H 0 0  9C  4C, 9G RICE     DRY SEEDED 4G 00 0 0 0 0 0 9C 3C, 8H 0 0 0 0 0 0  3C, 9G 4G 0 0  5C, 9G     2C, 8G G522 SORGHUM 0 00 0 0 0 0 0 5C, 9G 4C, 9G 0 0 2C, 8G 0 0 0  9C 9G     0 0  3C, 9G  3C, 9H CHEAT GRASS 5G 00 0 0 0 0 0 9C 9G 0 0 5G 0 0 0  2C,     8G 5G 0 0 -- --  USH11 SUGARBEET 3C, 5G 00 0 0 0 3C, 9H 3C, 8H 9C 6G 0 0     0 0 0 0 10C 9C 0 0 10C  9C VELVETLEAF 3C, 5G 1H0 0 0 0 3C, 9G 5G 9C 2C,     6G 8G 0 4G 0 3G 0  5C, 9G 3C, 8G 0 0 10C  5C, 9G GIANT FOXTAIL 5G 00 0 0     0 0 0 9C 3C, 8G 0 0 2G 0 2G 0  4C, 9H 3C, 7G 0 0  4C, 9G  0 KLAGES     BARLEY 4G 00 0 0 0 0 0 2C, 9G 2C, 8G 0 0 3G 0 0 0  3C, 8G 2C, 5G 0 0  7G      3G DOWNY BROME               -- -- -- -- -- --  9C      9C                    POSOL CMPD 113 CMPD 114 CMPD 115 CMPD 116 CMPD     117 CMPD 118 CMPD 119 CMPD 120 CMPD 121 RATE = KG/HA 0.05 0.01  0.05     0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05 0.01 0.05     0.01       COKER COTTON  3C, 9H 3C, 7G 6G 0 2C, 2G 0 10C  9C  5C, 9G  9C  9C  9C     9C  6C, 9G  9C 3C, 8H  5C, 9G 4C, 8G CULT MORNINGLRY 10C 3C, 8G 0 0 1C 0      9C  9C 10C 10C 10C 10C  4C, 8H  2C, 6G 10C 4C, 9G 10C 4C, 9H COCKLEBUR     9C 4C, 9G 3C, 7G 7G 3C, 8G 2H 10C 10C 10C 10C 10C 10C 10C 10C 10C 5C, 9G     10C 4C, 9H PURPLE NUTSEDGE  9C 2C, 8G 3G 0 0 0 10C 10C 10C  9C 10C --     9C  9C  7G 0  6G 0 LARGE CRABGRASS  0 0 0 0 0 0  3C, 5G  2G  3C, 9G  3G     7G  6G  4C, 9G  2C, 7G  2C, 7G 5G  3C, 8G 2G BARNYARDGRASS  3C, 9G 3C,     7G 3C, 3G 0 3C, 9H 3C, 7G  9C  9C  9C  5C, 9G 10C  5C, 9H 10C  9C  9C     4C, 8H  9C 9C WILD OATS  0 0 3G 0 3C, 7G 2G  5C, 9G  2C, 7G  3C, 9G  9G     9G  7G  3C, 9G  2C, 9G  3C, 9G 3C, 9G  3C, 9G 4C, 9G ERA WHEAT  0 0 3G 0     3C, 6G 2G  5C, 9G  9G  2C, 9G  9G  2C, 9G  8G  3C, 9G  9G  7G 5G  4C, 9G     9G G4646 CORN  3C, 7H 3C, 7H 3C, 7G 2C, 6G 5C, 9G 2C, 7H  7U, 9C  5U, 9C      4C, 9G  9G  5C, 9G  2C, 7H  6C, 9G  3C, 9G  9C 3C, 9G  6U, 9G 6U, 9G     WILLMS SOYBEANS  2H 0 3C, 7G 2H 2H 0  9C  9C  9C  6C, 9G  5C, 9G  3C, 8H      6C, 9G  5C, 9G  4C, 9G 5C, 9G  6C, 9G 5C, 9G RICE DRY SEEDED  7G 2C, 5G     2G 0 5C, 9G 4C, 9G  9C  9C  6C, 9G  5C, 9G  5C, 9G  4C, 9G  9C  5C, 9G     9C 5C,9G  9C 5C, 9G G522 SORGHUM  3C, 9G 3C, 9G 3G 3G 3C, 9G 3C, 8G  5C,     9G  9G  4C, 9G  9G  6C, 9G  9H  5C, 9G  4C, 9G  9G 3C, 8H  3C, 9G 9G     CHEAT GRASS -- -- -- -- -- --  9C  9C  5C, 9G  9G  9G  7G  6C, 9G  3C,     9G  5C, 9G 3C, 9G  9C 9G USH11 SUGARBEET  9C 3C, 7H 5G 0 4C, 9H 3C, 7H     10C  9C 10C 10C 10C  9C 10C  9C 10C 9C 10C 4C, 8H VELVETLEAF  9C 2C, 7G     3C, 8G 2C, 7G 0 0 10C 10C 10C  9C  9C  9G 10C 10C  9G 4C, 9H 10C 5C, 9H     GIANT FOXTAIL  0 0 4G 0 3C, 7G 2G  9C  4C, 9G 10C  2C, 9G  4C, 9G  3C,     8G 10C  3C, 9G  4C, 9G 3C, 6G 10C 4C, 9G KLAGES BARLEY  2G 0 3G 0 3G 3G     2C, 9G  7G  5C, 9G  9G  9G  5G  6C, 9G  3C, 9G  6G 3G  4C, 9G 4G DOWNY     BROME      3C, 9G 3G 2C, 5G 2G 9C 2C, 5G -- --

It is noted that a few compounds such as compounds 6, 19, 20, 26, 32,37-39, 44, 49, 54-59, 76-78 and 88 show little or no herbicidal activityat the rate tested. It is thought they would show more herbicidalactivity at higher rates.

TEST B Postemergence

Three round pans (25 cm diameter by 12.5 cm deep) were filled withSassafras sandy loam soil. One pan was planted with nutsedge (Cyperusrotundus) tubers, crabgrass (Digitaria sanguinalis), sicklepod (Cassiaobtusifolia), jimsonweed (Datura stramonium) velvetleaf (Abutilontheophrasti), chickweed (Stellaria media), lambsquarters (Chenopodiumalbum), rice (Oryza sativa, variety California Rice Coop. M101) andteaweed (Sida spinosa). The second pot was planted with green foxtail(Setaria viridis), cocklebur (Xanthium pensylvanicum), morningglory(Ipomoea coccinea, variety Scarlet O'Hara), cotton (Gossypium hirsutum,variety Coker 315), johnsongrass (Sorghum halepense), barnyardgrass(Echinochloa crus-galli), corn (Zea mays, variety Funk G4646), soybeans(Glycine max, variety Williams) and giant foxtail (Setaria faberi). Thethird pot was planted with wheat (Triticum aestivum, variety Eraspring), barley (Hordeum vulgare, variety Klages spring), wild buckwheat(Polgonum convolvulus), cheatgrass (Bromus secalinus), sugarbeet (Betavulgaris, variety Union Sugarbeet Co. USH11), wild oats (Avena fatua),field violet (Viola arvensis), blackgrass (Alopecurus myosuroides), andrape (Brassica napus, variety Altex). The plants were grown forapproximately days, then sprayed Postemergence with the chemicalsdissolved in a non-phytotoxic solvent.

Preemergence

Three round pans (25 cm diameter by 12.5 cm deep) were filled withSassafras sandy loam soil. One pan was planted with nutsedge tubers,crabgrass, sicklepod, jimsonweed, velvetleaf, chickweed, lambsquarters,rice and teaweed. The second pot was planted with green foxtail,cocklebur, morningglory, cotton, johnsongrass, barnyardgrass, corn,soybean and giant foxtail. The third pot was Planted with wheat, barley,wild buckwheat, cheatgrass, sugarbeet, wild oat, field violet,blackgrass and rape. The three pans were sprayed preemergence with thechemicals dissolved in a non-phytotoxic solvent.

Treated plants and controls were maintained in the greenhouse for 24days, then all treated plants were compared to controls and visuallyrated for plant response.

Response ratings are based on a scale of 0 to 100 where 0=no effect and100=complete control. A dash (--) response means no test.

Response ratings are contained in Table B.

                                      TABLE B                                     __________________________________________________________________________    PREEMERGENCE                                                                           Cmpd 1        Cmpd 21     Cmpd 46    Cmpd 60    Cmpd 64              RATE (g/ha)                                                                            1 4 16  62 250                                                                              1 4   16 62 4 16                                                                              62 250 4 16 62 250                                                                              4 16                 __________________________________________________________________________    Barley   20                                                                              30                                                                              80  80 90 30                                                                              50  80 90 20                                                                              40                                                                              60 80  20                                                                              30 30 90  0 30                Barnyardgrass                                                                           0                                                                              20                                                                              100 95 95 30                                                                              60  90 100                                                                              60                                                                              90                                                                              100                                                                              100 20                                                                              100                                                                              100                                                                              100                                                                              30 50                Blackgrass                                                                              0                                                                              20                                                                              80  85 100                                                                              60                                                                              70  80 90 50                                                                              70                                                                              80 90  70                                                                              80 100                                                                              100                                                                              30 70                Cheatgrass                                                                             30                                                                              70                                                                              90  100                                                                              100                                                                              30                                                                              70  100                                                                              100                                                                              60                                                                              70                                                                              80 90  30                                                                              70 100                                                                              100                                                                              50 70                Chickweed                                                                              --                                                                              --                                                                              --  -- -- --                                                                              --  -- -- 30                                                                              50                                                                              70 90  60                                                                              100                                                                              100                                                                              100                                                                              30 50                Cocklebur                                                                               0                                                                               0                                                                              30  85 90  0                                                                              30  50 70  0                                                                              30                                                                              50 70   0                                                                              50 60 90 50 70                Corn      0                                                                               0                                                                               0   0 10  0                                                                               0   0  0  0                                                                               0                                                                               0 30   0                                                                              20 30 40  0 30                Cotton    0                                                                              10                                                                              85  85 90  0                                                                              30  50 80  0                                                                              30                                                                              40 60   0                                                                              50 90 90 30 50                Crabgrass                                                                               0                                                                               0                                                                              40  50 75 30                                                                              50  70 90  0                                                                              30                                                                              50 70  60                                                                              60 70 80  0 30                Field violet                                                                           --                                                                              --                                                                              --  -- -- 30                                                                              50  70 90 --                                                                              --                                                                              -- --  --                                                                              -- -- -- -- --                Giant foxtail                                                                          20                                                                              20                                                                              80  85 90 30                                                                              70  90 100                                                                              50                                                                              80                                                                              90 100 --                                                                              -- -- --  0 50                Green foxtail                                                                          20                                                                              90                                                                              95  100                                                                              99 30                                                                              70  100                                                                              100                                                                              30                                                                              50                                                                              80 100  0                                                                              70 100                                                                              100                                                                              30 50                Jimsonweed                                                                             --                                                                               0                                                                              --  50 -- 60                                                                              70  80 90  0                                                                              30                                                                              60 90   0                                                                              50 70 80 30 50                Johnsongrass                                                                           60                                                                              85                                                                              90  100                                                                              100                                                                              50                                                                              70  80 90 50                                                                              70                                                                              80 90  70                                                                              80 100                                                                              100                                                                              30 50                Lambsquarters                                                                           0                                                                               0                                                                              50  70 80 50                                                                              60  70 90 30                                                                              50                                                                              80 90  30                                                                              50 90 100                                                                              30 50                Morningglory                                                                            0                                                                               0                                                                              20  80 95  0                                                                              30  60 90 30                                                                              50                                                                              70 90  20                                                                              80 90 100                                                                              50 80                Nutsedge 20                                                                              30                                                                              80  90 95  0                                                                              30  80 100                                                                              30                                                                              60                                                                              90 100  0                                                                              80 90 100                                                                              80 90                Rape      0                                                                              50                                                                              80  90 95 70                                                                              90  100                                                                              100                                                                              50                                                                              70                                                                              90 100 80                                                                              90 90 100                                                                              80 100               Rice     20                                                                              85                                                                              90  95 100                                                                              60                                                                              100 100                                                                              100                                                                              80                                                                              90                                                                              100                                                                              100 90                                                                              90 100                                                                              100                                                                              50 70                Sicklepod                                                                              --                                                                               0                                                                              --  -- -- --                                                                              --  -- -- 30                                                                              60                                                                              90 100 50                                                                              80 90 90 30 50                Soybean   0                                                                               0                                                                               0  10 30  0                                                                               0  30 90  0                                                                               0                                                                              70 --  30                                                                              60 90 100                                                                              30 60                Sugarbeet                                                                              20                                                                              60                                                                              70  80 90 30                                                                              60  90 100                                                                              70                                                                              90                                                                              100                                                                              --  80                                                                              90 90 90 80 90                Teaweed  --                                                                              --                                                                              30  80 80 30                                                                              50  70 90  0                                                                              30                                                                              50 80  50                                                                              70 90 90 30 50                Velvetleaf                                                                              0                                                                              20                                                                              30  40 70 30                                                                              50  70 90 30                                                                              60                                                                              90 100 30                                                                              40 80 100                                                                              50 70                Wheat     0                                                                              20                                                                              30  80 90  0                                                                              30  60 90 30                                                                              50                                                                              70 80  30                                                                              40 60 90 30 50                Wild buckwheat                                                                          0                                                                              50                                                                              70  80 90 70                                                                              80  90 90 30                                                                              50                                                                              70 90  50                                                                              70 80 90 70 80                Wild oat 10                                                                              20                                                                              30  60 70  0                                                                               0  30 80  0                                                                              30                                                                              40 60   0                                                                              30 50 70  0 30                __________________________________________________________________________    PREEMERGENCE                                                                           Cmpd 64                                                                             Cmpd 65    Cmpd 66   Cmpd 67   Cmpd 68   Cmpd 92                RATE (g/ha)                                                                           62 250                                                                              1 4  16 62 1 4 16 62 1 4 16 62 1 4 16 62 16 62                 __________________________________________________________________________    Barley   60 90 20                                                                              40 80 100                                                                               0                                                                              30                                                                              60 90  0                                                                              20                                                                              70 100                                                                               0                                                                              40                                                                              80 90     40                                                                     70                       Barnyardgrass                                                                          70 90  0                                                                              30 40 50  0                                                                               0                                                                              20 30  0                                                                              20                                                                              100                                                                              100                                                                              20                                                                              30                                                                              60 80     100                                                                    100                      Blackgrass                                                                             80 90 40                                                                              50 90 100                                                                              30                                                                              50                                                                              90 100                                                                              30                                                                              50                                                                              80 90 30                                                                              50                                                                              80 90     70                                                                     100                      Cheatgrass                                                                             80 90 70                                                                              80 100                                                                              100                                                                              60                                                                              70                                                                              100                                                                              100                                                                              30                                                                              70                                                                              80 100                                                                              30                                                                              40                                                                              100                                                                              100    70                                                                     90                       Chickweed                                                                              70 90 70                                                                              90 100                                                                              100                                                                              70                                                                              80                                                                              90 100                                                                              30                                                                              70                                                                              80 90 40                                                                              60                                                                              70 80     50                                                                     80                       Cocklebur                                                                              80 90  0                                                                              20 90 100                                                                               0                                                                               0                                                                              20 80  0                                                                              20                                                                              70 80  0                                                                              20                                                                              30 40     30                                                                     50                       Corn     60 90  0                                                                               0 90 90  0                                                                               0                                                                              50 70  0                                                                              20                                                                              80 100                                                                               0                                                                               0                                                                               0 40     40                Cotton   70 90  0                                                                              20 80 100                                                                               0                                                                               0                                                                               0  0 --                                                                               0                                                                              20 90  0                                                                               0                                                                              20 40     50                                                                     90                       Crabgrass                                                                              50 70 20                                                                              60 90 90 20                                                                              70                                                                              100                                                                              100                                                                              30                                                                              70                                                                              100                                                                              100                                                                               0                                                                              40                                                                              100                                                                              100    60                                                                     70                       Field violet                                                                           -- -- --                                                                              -- -- -- --                                                                              --                                                                              -- -- --                                                                              --                                                                              -- -- --                                                                              --                                                                              -- --     --                                                                     --                       Giant foxtail                                                                          70 90  0                                                                              20 100                                                                              100                                                                              20                                                                              40                                                                              70 90 20                                                                              40                                                                              100                                                                              100                                                                              20                                                                              40                                                                              90 100    --                                                                     --                       Green foxtail                                                                          70 90  0                                                                              20 100                                                                              100                                                                               0                                                                              20                                                                              90 100                                                                               0                                                                              20                                                                              90 100                                                                               0                                                                              30                                                                              90 100    90                                                                     100                      Jimsonweed                                                                             70 90  0                                                                              30 100                                                                              100                                                                              20                                                                              20                                                                              40 80  0                                                                              40                                                                              100                                                                              100                                                                               0                                                                              30                                                                              70 90     70                                                                     90                       Johnsongrass                                                                           70 90  0                                                                              30 90 90  0                                                                               0                                                                              30 70  0                                                                              30                                                                              100                                                                              100                                                                              20                                                                              30                                                                              90 90     90                                                                     100                      Lambsquarters                                                                          70 90 20                                                                              40 100                                                                              100                                                                               0                                                                               0                                                                              20 80  0                                                                              30                                                                              90 100                                                                               0                                                                              30                                                                              70 90     90                                                                     100                      Morningglory                                                                           90 100                                                                               0                                                                              30 100                                                                              100                                                                               0                                                                              20                                                                              90 90  0                                                                              20                                                                              30 100                                                                               0                                                                              30                                                                              50 80     70                                                                     90                       Nutsedge 100                                                                              100                                                                               0                                                                              30 90 90  0                                                                              20                                                                              40 80 20                                                                              60                                                                              100                                                                              100                                                                               0                                                                              30                                                                              100                                                                              100    80                                                                     90                       Rape     100                                                                              100                                                                              70                                                                              100                                                                              100                                                                              100                                                                              40                                                                              60                                                                              90 100                                                                              30                                                                              70                                                                              100                                                                              100                                                                              30                                                                              70                                                                              100                                                                              100    90                                                                     100                      Rice     100                                                                              100                                                                               0                                                                              20 100                                                                              100                                                                               0                                                                              20                                                                              60 100                                                                              20                                                                              50                                                                              100                                                                              100                                                                               0                                                                              30                                                                              100                                                                              100                                                                           100                      Sicklepod                                                                              70 90  0                                                                              50 90 100                                                                              20                                                                              40                                                                              80 100                                                                               0                                                                              20                                                                              30 40  0                                                                              30                                                                              80 90     60                                                                     80                       Soybean  80 90  0                                                                               0 30 50  0                                                                               0                                                                              30 80  0                                                                               0                                                                              40 80  0                                                                               0                                                                              30 70     70                                                                     100                      Sugarbeet                                                                              100                                                                              100                                                                              70                                                                              90 100                                                                              100                                                                              40                                                                              60                                                                              100                                                                              100                                                                              60                                                                              70                                                                              100                                                                              100                                                                              30                                                                              40                                                                              100                                                                              100    80                                                                     90                       Teaweed  70 90 20                                                                              50 100                                                                              100                                                                              20                                                                              30                                                                              90 90  0                                                                              20                                                                              70 80  0                                                                              30                                                                              80 80     --                                                                     90                       Velvetleaf                                                                             90 100                                                                               0                                                                              20 80 90  0                                                                               0                                                                              40 60  0                                                                              30                                                                              70 100                                                                               0                                                                              30                                                                              80 90     50                                                                     60                       Wheat    70 90  0                                                                              60 80 100                                                                               0                                                                              30                                                                              90 100                                                                               0                                                                              20                                                                              50 90  0                                                                              30                                                                              60 100    40                                                                     70                       Wild buckwheat                                                                         90 95 80                                                                              100                                                                              100                                                                              100                                                                               0                                                                              40                                                                              100                                                                              100                                                                              60                                                                              90                                                                              100                                                                              100                                                                              40                                                                              70                                                                              90 90     80                                                                     80                       Wild oat 50 70 20                                                                              40 80 100                                                                              20                                                                              30                                                                              40 90  0                                                                              20                                                                              30 40 40                                                                              50                                                                              80 100    30                                                                     50                       __________________________________________________________________________                    PREEMERGENCE                                                                           Cmpd 93  Cmpd 96   Cmpd 100   Cmpd 106                               RATE (g/ha)                                                                            1 4 16                                                                              62 1 4 16 62 1 4  16 62 16                                                                              62 250               __________________________________________________________________________                    Barley    0                                                                              20                                                                              40                                                                              60  0                                                                              20                                                                              30 80 30                                                                              50 70 90 50                                                                              80 90                                Barnyardgrass                                                                           0                                                                              30                                                                              50                                                                              70  0                                                                              20                                                                              80 80 30                                                                              50 80 100                                                                              20                                                                              40 100                               Blackgrass                                                                             30                                                                              50                                                                              70                                                                              100                                                                               0                                                                              50                                                                              50 70 50                                                                              60 70 90 80                                                                              100                                                                              100                               Cheatgrass                                                                              0                                                                              30                                                                              50                                                                              70  0                                                                              30                                                                              50 80 50                                                                              70 80 90 70                                                                              100                                                                              100                               Chickweed                                                                              --                                                                              --                                                                              --                                                                              --  0                                                                               0                                                                              40 40 30                                                                              50 70 90  0                                                                              10 20                                Cocklebur                                                                               0                                                                               0                                                                              30                                                                              40  0                                                                              30                                                                              50 60  0                                                                              30 60 90  0                                                                              40 80                                Corn      0                                                                               0                                                                               0                                                                               0  0                                                                               0                                                                               0  0  0                                                                               0  0  0  0                                                                               0 10                                Cotton    0                                                                               0                                                                               0                                                                              20  0                                                                               0                                                                              40 70  0                                                                              30 50 60  0                                                                              10 20                                Crabgrass                                                                               0                                                                              20                                                                              30                                                                              60  0                                                                               0                                                                              40 100                                                                               0                                                                              30 50 80 40                                                                              80 80                                Field violet                                                                           20                                                                              30                                                                              60                                                                              80 --                                                                              --                                                                              -- -- --                                                                              -- -- -- --                                                                              -- --                                Giant foxtail                                                                          30                                                                              50                                                                              70                                                                              80  0                                                                              20                                                                              90 100                                                                              70                                                                              90 100                                                                              100                                                                              40                                                                              90 100                               Green foxtail                                                                           0                                                                               0                                                                              30                                                                              60  0                                                                              70                                                                              100                                                                              100                                                                              50                                                                              70 90 100                                                                              40                                                                              90 100                               Jimsonweed                                                                              0                                                                              30                                                                              60                                                                              90  0                                                                              60                                                                              80 90  0                                                                              30 50 80  0                                                                              -- 20                                Johnsongrass                                                                           70                                                                              80                                                                              90                                                                              100                                                                               0                                                                              40                                                                              70 90 50                                                                              70 80 90 70                                                                              90 100                               Lambsquarters                                                                           0                                                                              30                                                                              60                                                                              90  0                                                                              20                                                                              30 70 70                                                                              100                                                                              100                                                                              100                                                                              80                                                                              90 100                               Morningglory                                                                            0                                                                              20                                                                              30                                                                              50  0                                                                               0                                                                              30 60  0                                                                              30 50 80 20                                                                              40 50                                Nutsedge  0                                                                               0                                                                              30                                                                              70  0                                                                              20                                                                              40 60  0                                                                              30 60 90 40                                                                              50 70                                Rape     50                                                                              70                                                                              80                                                                              90  0                                                                              70                                                                              70 90 70                                                                              100                                                                              100                                                                              100                                                                              80                                                                              90 100                               Rice     30                                                                              50                                                                              90                                                                              100                                                                               0                                                                              50                                                                              90 90 30                                                                              60 80 90 80                                                                              100                                                                              100                               Sicklepod                                                                               0                                                                              20                                                                              30                                                                              50  0                                                                               0                                                                              40 80 30                                                                              50 70 90  0                                                                              20 60                                Soybean   0                                                                               0                                                                               0                                                                               0  0                                                                              20                                                                              50 60  0                                                                              30 40 60  0                                                                               0 20                                Sugarbeet                                                                              30                                                                              50                                                                              80                                                                              90  0                                                                               0                                                                              60 80 70                                                                              90 100                                                                              100                                                                              30                                                                              80 100                               Teaweed  30                                                                              50                                                                              70                                                                              90  0                                                                               0                                                                              30 30  0                                                                              30 50 70 30                                                                              50 70                                Velvetleaf                                                                              0                                                                              30                                                                              50                                                                              70  0                                                                              30                                                                              30 40 30                                                                              60 90 95  0                                                                              20 60                                Wheat      0                                                                              0                                                                              20                                                                              40  0                                                                               0                                                                              30 60  0                                                                              30 60 90 20                                                                              40 60                                Wild buckwheat                                                                          0                                                                              30                                                                              50                                                                              70  0                                                                               0                                                                              50 90  0                                                                              30 60 90 30                                                                              60 80                                Wild oat  0                                                                               0                                                                              30                                                                              50  0                                                                              30                                                                              40 40  0                                                                               0 30 50 20                                                                              60 80                __________________________________________________________________________    POSTEMERGENCE                                                                          Cmpd 1         Cmpd 21         Cmpd 46    Cmpd 60                    RATE (g/ha)                                                                            0.25                                                                             1  4  16 62 0.25                                                                              1 4  16 62  1 4 16 62  1 4  16 62                 __________________________________________________________________________    Barley    0  0 30 80 90 20  20                                                                              60 70 70  30                                                                              50                                                                              60 70   0                                                                              40 60 90                 Barnyardgrass                                                                          30 60 100                                                                              100                                                                              100                                                                              50  80                                                                              95 100                                                                              100 50                                                                              70                                                                              80 90  60                                                                              100                                                                              100                                                                              100                Blackgrass                                                                             50 50 70 85 100                                                                               0  50                                                                              80 90 90  30                                                                              50                                                                              70 100 60                                                                              100                                                                              100                                                                              100                Cheatgrass                                                                             20 30 65 85 95 20  30                                                                              50 90 100 30                                                                              50                                                                              70 90  40                                                                              60 80 100                Chickweed                                                                              -- -- -- -- -- --  --                                                                              -- -- --  30                                                                              50                                                                              70 90  30                                                                              60 90 100                Cocklebur                                                                               0 20 80 80 100                                                                               0   0                                                                              40 80 100 30                                                                              40                                                                              50 60  50                                                                              100                                                                              100                                                                              100                Corn      0  0  0  0 10  0   0                                                                               0  0  0   0                                                                               0                                                                               0  0  --                                                                              20 50 70                 Cotton    0 20 30 80 85  0  30                                                                              60 80 100  0                                                                              30                                                                              50 60  20                                                                              30 90 100                Crabgrass                                                                              30 20 20 50 60  0   0                                                                               0 70 80   0                                                                               0                                                                              30 50   0                                                                               0 30 40                 Field violet                                                                           --  0  0 20 --  0  30                                                                              40 80 80  --                                                                              --                                                                              -- --  --                                                                              -- -- --                 Giant foxtail                                                                           0 20 50 70 85 40  70                                                                              100                                                                              100                                                                              100 30                                                                              50                                                                              80 90  20                                                                              20 80 90                 Green foxtail                                                                           0 20 30 75 85 60  90                                                                              100                                                                              100                                                                              100 30                                                                              50                                                                              70 80  30                                                                              50 80 90                 Jimsonweed                                                                              0  0 10 20 30  0   0                                                                              20 50 80   0                                                                               0                                                                              30 60  20                                                                              30 40 60                 Johnsongrass                                                                           60 80 100                                                                              100                                                                              100                                                                              70  80                                                                              100                                                                              100                                                                              100 30                                                                              60                                                                              90 100 20                                                                              90 100                                                                              100                Lambsquarters                                                                           0  0 20 20 50  0  --                                                                               0 -- 100  0                                                                               0                                                                              30 50   0                                                                              50 50 90                 Morningglory                                                                           10 30 50 85 90  0  20                                                                              95 95 100 30                                                                              50                                                                              70 80  --                                                                              60 60 80                 Nutsedge  0 30 70 75 80  0  30                                                                              40 70 100  0                                                                              30                                                                              60 90  20                                                                              30 80 90                 Rape     20 60 90 100                                                                              90 50  80                                                                              100                                                                              100                                                                              100 60                                                                              90                                                                              100                                                                              100 80                                                                              100                                                                              100                                                                              100                Rice     20 40 70 90 100                                                                                0 40                                                                              90 100                                                                              100 30                                                                              50                                                                              70 90  60                                                                              60 90 100                Sicklepod                                                                               0 50 80 70 100                                                                               0  30                                                                              90 100                                                                              100  0                                                                              30                                                                              60 90  30                                                                              60 90 100                Soybean   0  0 10 20 70 40  50                                                                              80 90 90   0                                                                              30                                                                              60 90  60                                                                              80 90 100                Sugarbeet                                                                              10  0 30 80 100                                                                               0  20                                                                              40 70 80  30                                                                              50                                                                              70 90  --                                                                              60 80 100                Teaweed   0 20 30 60 70  0  --                                                                              -- -- 80   0                                                                              20                                                                              40 60  20                                                                              30 40 60                 Velvetleaf                                                                              0 20 40 60 100                                                                               0   0                                                                              50 90 100 30                                                                              60                                                                              80 100 70                                                                              80 100                                                                              100                Wheat    10 10 60 100                                                                              100                                                                              50  60                                                                              60 100                                                                              100 30                                                                              50                                                                              80 100  0                                                                              30 60 100                Wild buckwheat                                                                          0 30 40 70 -- 20  20                                                                              50 60 80  30                                                                              50                                                                              70 90  70                                                                              70 80 90                 Wild oat  0  0 20 60 100                                                                                0 20                                                                              70 80 100  0                                                                               0                                                                              30 60   0                                                                              40 60 80                 __________________________________________________________________________    POSTEMERGENCE                                                                          Cmpd 64     Cmpd 65      Cmpd 66     Cmpd 67     Cmpd 68             RATE (g/ha)                                                                            1  4  16 62 0.25                                                                             1  4  16  0.25                                                                             1 4  16  1 4  16 62  1 4                 __________________________________________________________________________    Barley    0 30 50 70 30 70 100                                                                              100 20 40                                                                              80 100 20                                                                              40 80 90  40                                                                              90                Barnyardgrass                                                                          30 50 80 100                                                                              60 100                                                                              100                                                                              100 30 80                                                                              100                                                                              100 90                                                                              100                                                                              100                                                                              100 60                                                                              100               Blackgrass                                                                             30 50 70 90 30 60 80 90  20 30                                                                              40 90  40                                                                              80 90 90  30                                                                              80                Cheatgrass                                                                              0 30 50 70 70 90 90 100 30 60                                                                              90 90  40                                                                              80 90 100 80                                                                              90                Chickweed                                                                              30 50 70 90 50 90 100                                                                              100 20 50                                                                              90 100 40                                                                              60 90 100 40                                                                              70                Cocklebur                                                                              70 80 90 100                                                                              50 80 100                                                                              100  0 30                                                                              90 100 40                                                                              60 100                                                                              100 40                                                                              80                Corn      0  0 20 60 90 100                                                                              100                                                                              100 30 50                                                                              90 100 30                                                                              80 100                                                                              100  0                                                                              20                Cotton   30 50 70 90  0 20 30 100  0  0                                                                              30 40   0                                                                              40 80 100  0                                                                              30                Crabgrass                                                                               0  0 30 50 30 60 90 100  0 40                                                                              60 100 30                                                                              40 80 100 30                                                                              70                Field violet                                                                           -- -- -- -- -- -- -- --  -- --                                                                              -- --  --                                                                              -- -- --  --                                                                              --                Giant foxtail                                                                           0 30 50 80 80 100                                                                              100                                                                              100 30 50                                                                              100                                                                              100  0                                                                              30 100                                                                              100 30                                                                              90                Green foxtail                                                                           0 30 50 70 70 100                                                                              100                                                                              100  0 50                                                                              90 100 20                                                                              40 70 90  40                                                                              80                Jimsonweed                                                                              0 30 60 90  0 20 80 100  0 60                                                                              90 100 70                                                                              100                                                                              100                                                                              100 70                                                                              100               Johnsongrass                                                                           30 50 70 90 60 100                                                                              100                                                                              100 40 60                                                                              80 100 80                                                                              100                                                                              100                                                                              100 70                                                                              90                Lambsquarters                                                                          60 70 80 90 80 100                                                                              100                                                                              100 50 60                                                                              90 100 80                                                                              100                                                                              100                                                                              100 70                                                                              90                Morningglory                                                                           50 70 90 100                                                                              40 90 100                                                                              100 20 40                                                                              90 100 60                                                                              90 100                                                                              100 30                                                                              80                Nutsedge 70 100                                                                              100                                                                              100                                                                              30 80 100                                                                              100  0 20                                                                              40 100 30                                                                              80 90 100 20                                                                              70                Rape     100                                                                              100                                                                              100                                                                              100                                                                              80 100                                                                              100                                                                              100 30 90                                                                              100                                                                              100 80                                                                              100                                                                              100                                                                              100 40                                                                              100               Rice     30 50 70 90 30 100                                                                              100                                                                              100 20 40                                                                              90 100 30                                                                              80 100                                                                              100 50                                                                              90                Sicklepod                                                                              50 70 100                                                                              100                                                                              50 90 100                                                                              100  0 30                                                                              90 100 30                                                                              100                                                                              100                                                                              100 30                                                                              90                Soybean  80 90 100                                                                              100                                                                              80 100                                                                              100                                                                              100 50 80                                                                              100                                                                              100 60                                                                              90 100                                                                              100 70                                                                              100               Sugarbeet                                                                              50 70 90 100                                                                              80 100                                                                              100                                                                              100 30 50                                                                              100                                                                              100 80                                                                              100                                                                              100                                                                              100 40                                                                              100               Teaweed  50 60 70 80  0 60 100                                                                              100  0 30                                                                              70 90  30                                                                              70 90 100 20                                                                              80                Velvetleaf                                                                             70 80 100                                                                              100                                                                              60 100                                                                              100                                                                              100 20 70                                                                              90 100 50                                                                              80 90 100 40                                                                              90                Wheat     0 30 50 70 80 90 100                                                                              100 40 80                                                                              90 100  0                                                                              30 40 70  60                                                                              90                Wild buckwheat                                                                         30 60 80 90 40 80 100                                                                              100  0 30                                                                              50 80  30                                                                              60 80 100 30                                                                              70                Wild oat  0  0 30 60 40 90 100                                                                              100 20 80                                                                              90 100 20                                                                              30 80 90  70                                                                              90                __________________________________________________________________________    POSTEMERGENCE                                                                          Cmpd 68                                                                               Cmpd 92                                                                             Cmpd 93       Cmpd 96     Cmpd 100                     RATE (g/ha)                                                                            16 62  4  16  1  4   16 62 0.25                                                                              1  4 16  1  4   16 62                 __________________________________________________________________________    Barley   100                                                                              100 70 80   0  0   0 10  0  20 40                                                                              90  50 70  100                                                                              100                Barnyardgrass                                                                          100                                                                              100 60 90  30 40  60 70 30  40 90                                                                              100 30 40  80 100                Blackgrass                                                                             100                                                                              100 90 90  50 50  70 80  0   0 70                                                                              80  70 90  100                                                                              100                Cheatgrass                                                                             100                                                                              100 90 100  0  0  30 70  0   0 70                                                                              70  70 80  100                                                                              100                Chickweed                                                                              90 100 70 90  -- --  -- --  0   0 40                                                                              60  50 70  90 100                Cocklebur                                                                              100                                                                              100 80 100 60 60  70 90  0   0 30                                                                              70  70 100 100                                                                              100                Corn     90 100  0  0   0  0   0 10  0   0 20                                                                              80  --  0  20 40                 Cotton   80 100 90 90  -- 40  50 70  0   0  0                                                                              20  50 80  90 90                 Crabgrass                                                                              90 100  0 60   0  0   0 20  0   0 40                                                                              80   0  0  50 60                 Field violet                                                                           -- --  -- --   0  0   0 30 --  -- --                                                                              --  -- --  -- --                 Giant foxtail                                                                          100                                                                              100 90 90  --  0  20 60  0  -- 40                                                                              100 40 50  90 100                Green foxtail                                                                          100                                                                              100 70 80  -- 40  50 90  0  40 70                                                                              90  30 50  80 90                 Jimsonweed                                                                             100                                                                              100 50 50  60 80  90 100                                                                               0  30 50                                                                              60   0  0  20 40                 Johnsongrass                                                                           100                                                                              100 100                                                                              100 90 90  100                                                                              100                                                                               0  70 90                                                                              100 70 100 100                                                                              100                Lambsquarters                                                                          100                                                                              100 80 90  -- 50  60 70  0   0  0                                                                              40  50 70  100                                                                              100                Morningglory                                                                           100                                                                              100 70 100 70 70  80 80  0   0 30                                                                              60  60 90  100                                                                              100                Nutsedge 80 100  0 60   0  0  30 40  0  20 30                                                                              60   0 30  60 100                Rape     100                                                                              100 100                                                                              100 100                                                                              100 100                                                                              100                                                                              20  30 90                                                                              100 100                                                                              100 100                                                                              100                Rice     100                                                                              100 60 100  0  0  60 80  0   0 50                                                                              90  50 90  100                                                                              100                Sicklepod                                                                              100                                                                              100 90 100  0  0  40 70  0   0 40                                                                              80  50 70  100                                                                              100                Soybean  100                                                                              100 70 100 --  0  10 50 30  40 90                                                                              90  80 80  100                                                                              100                Sugarbeet                                                                              100                                                                              100 100                                                                              100 -- 30  80 100                                                                               0  20 30                                                                              60  90 100 100                                                                              100                Teaweed  90 90  20 60   0  0   0 50  0   0 20                                                                              70   0 30  50 70                 Velvetleaf                                                                             100                                                                              100 70 70   0  0  20 70  0   0 20                                                                              60  30 80  90 100                Wheat    100                                                                              100 90 90   0  0  10 40 20  40 50                                                                              60  50 70  100                                                                              100                Wild buckwheat                                                                         90 100 70 80   0  0  30 30  0   0 --                                                                              80  30 60  90 100                Wild oat 100                                                                              100 60 80   0  0   0 50  0  30 50                                                                              70  40 70  100                                                                              100                __________________________________________________________________________                                               POSTEMERGENCE                                                                          Cmpd 106                                                             RATE (g/ha)                                                                            1 4  16 62                __________________________________________________________________________                                               Barley    0                                                                              30 50 90                                                           Barnyardgrass                                                                          30                                                                              60 90 100                                                          Blackgrass                                                                             50                                                                              70 90 90                                                           Cheatgrass                                                                              0                                                                              30 70 90                                                           Chickweed                                                                               0                                                                               0 30 70                                                           Cocklebur                                                                               0                                                                              50 70 100                                                          Corn      0                                                                               0  0 20                                                           Cotton    0                                                                               0 10 20                                                           Crabgrass                                                                               0                                                                               0  0  0                                                           Field violet                                                                           --                                                                              -- -- --                                                           Giant foxtail                                                                           0                                                                              20 40 90                                                           Green foxtail                                                                          20                                                                              40 80 90                                                           Jimsonweed                                                                              0                                                                               0 20 40                                                           Johnsongrass                                                                           50                                                                              50 70 90                                                           Lambsquarters                                                                          40                                                                              60 80 90                                                           Morningglory                                                                            0                                                                              50 90 90                                                           Nutsedge  0                                                                               0 20 30                                                           Rape     70                                                                              100                                                                              100                                                                              100                                                          Rice      0                                                                              30 70 100                                                          Sicklepod                                                                              --                                                                              20 -- 50                                                           Soybean   0                                                                              40 50 90                                                           Sugarbeet                                                                              40                                                                              70 80 90                                                           Teaweed   0                                                                               0 20 30                                                           Velvetleaf                                                                              0                                                                              30 70 90                                                           Wheat      0                                                                             40 80 100                                                          Wild buckwheat                                                                          0                                                                               0 50 70                                                           Wild oat  0                                                                              60 90 100               __________________________________________________________________________

TEST C Postemergence

Six round pots (17 cm diameter by 15 cm deep) were used to grow plantsto the treatment stage. Four were planted with seeds or tubers of fourspecies each and another with soybeans using Sassafras sandy loam as thegrowing media. The sixth pot was planted to corn using a Tama silt loam.During spraying, the soil of this pot was temporarily covered withperlite then later removed so any effects noted would be from foliaruptake only. A separate pot of corn (25.5 cm diameter by 19.5 cm deep)grown in Sassafras sandy loam was also included to determine foliar/soiltreatment effects on plant growth. Plants were grown 10 to 20 days andwere in the 2 to 5 leaf stage when sprayed postemergence with compoundsof the invention. Species included were as follows: G4646 corn [maize](Zea mays, variety Funk G4646), Williams soybeans (Glycine max, varietyWilliams), green foxtail (Setaria viridis), giant foxtail (Setariafaberi), fall panicum (Panicum dichotomiflorum), crabgrass (Digitariasanguinalis), barnyardgrass (Echinochloa crus-galli), johnsongrass(Sorghum halepense), G522 sorghum (Sorghum vulgare, variety Funk G522),nutsedge (Cyperus rotundus), velvetleaf (Abutilon theophrasti),cocklebur (Xanthium pensylvanicum), smartweed (Polygonum persicaria,lambsquarter (Chenopodium album), pigweed (Amaranthus retroflexus),ivyleaf morningglory (Ipomoea hederacea), jimsonweed (Daturastramonium), ragweed (Ambrosia artemisiifolia).

Preemergence

Plantings were made as above except all in Tama silt loam. Compoundswere sprayed preemergence the day after planting. All pots were thenwatered to simulate rainfall.

After treatment, all plantings were maintained in a greenhouse about 20days and then visually rated for plant response. Ratings are based on ascale of 0 to 100 where 0=no effect and 100=complete control. Responseratings are shown in Table C.

                                      TABLE C                                     __________________________________________________________________________    PRE                                                                                        CMPD 60           CMPD 92           CMPD 96                      RATE GM/HA   0016                                                                              0032 0064                                                                              0125 0016                                                                              0032 0064                                                                              0125 0016 0032                                                                              0064                __________________________________________________________________________    SOIL TYPE    TAM TAM  TAM TAM  TAM TAM  TAM TAM  TAM  TAM TAM                 G4646 CORN    0   0    0   0    0   0    0   0    0    0   0                  WILLMS SOYBEANS                                                                            30  40   60  85    0  25   50  80    0    0   0                  GREEN FOXTAIL                                                                              20  25   35  60    0  35   70  100   0   15  20                  GIANT FOXTAIL                                                                              20  20   30  40    0  30   70  95    0   15  20                  FALL PANICUM 70  80   95  100  20  45   85  95    0    0   0                  LARGE CRABGRASS                                                                             0   0   20  --    0  20   40  70    0    0   0                  BARNYARDGRASS                                                                              65  70   90  100  25  45   85  100   0   15  30                  JOHNSONGRASS 70  90   100 100  50  65   100 100   0   20  45                  G522 SORGHUM 75  100  100 100  45  55   90  100  20   35  55                  PURPLE NUTSEDGE                                                                            35  60   80  --    0  25   65  80    0    0   0                  VELVETLEAF    0   0    0  --    0   0    0  30    0    0  20                  COCKLEBUR     0   0    0  --    0   0    0  20    0   10  20                  LADY SMARTWEED                                                                             50  65   95  --   30  60   96  100  15   35  50                  LAMBSQUARTER 25  40   60  --   20  40   90  100   0    0   0                  REDROOT PIGWEED                                                                            50  60   90  --   50  70   100 100   0   25  45                  IVY MORNINGLORY                                                                             0   0    0  --    0   0    0  25    0    0   0                  JIMSONWEED    0   0    0  --    0   0    0  35    0    0   0                  __________________________________________________________________________    PRE                                                                                                              CMPD 96 CMPD 100                                                 RATE GM/HA   0125                                                                              0250                                                                              0016                                                                              0032                                                                              0064                                                                              0125                                                                              0250               __________________________________________________________________________                          SOIL TYPE    TAM TAM TAM TAM TAM TAM TAM                                      G4646 CORN    0   0   0   0    0  0  20                                       WILLMS SOYBEANS                                                                            20  45   0  25  40  70  80                                       GREEN FOXTAIL                                                                              35  50  25  45  85  95  100                                      GIANT FOXTAIL                                                                              35  50   0  35  70  95  100                                      FALL PANICUM  0  15  40  85  100 100 100                                      LARGE CRABGRASS                                                                             0  15   0  20  35  50  65                                       BARNYARDGRASS                                                                              70  85  35  60  100 100 100                                      JOHNSONGRASS 55  75  70  90  100 100 100                                      G522 SORGHUM 75  95  75  95  100 100 100                                      PURPLE NUTSEDGE                                                                             0   0  30  50  70  90  100                                      VELVETLEAF   30  40   0   0   0   0  25                                       COCKLEBUR    35  50   0   0  20  35  50                                       LADY SMARTWEED                                                                             60  75  40  70  95  100 100                                      LAMBSQUARTER 15  25  25  40  65  95  100                                      REDROOT PIGWEED                                                                            65  85  30  65  90  100 100                                      IVY MORNINGLORY                                                                             0   0   0   0   0   0  35                                       JIMSONWEED   15  20   0   0  30  45  70                 __________________________________________________________________________    POST                                                                                       CMPD 1            CMPD 21              CMPD 46                   RATE GM/HA   0004                                                                             0008                                                                             0016                                                                             0032                                                                             0064                                                                             0125                                                                             0002                                                                             0004                                                                             0008                                                                             0016                                                                             0032                                                                             0064                                                                             0125                                                                             0002                                                                              0004                                                                             0008               __________________________________________________________________________    SOIL TYPE    SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS SAS                                                                              SAS                G4646 CORN    0  0  0  0 25 40  0  0  0  0 10 20 70  0   0  0                 WILLMS SOYBEANS                                                                             0 20 35 50 65 85 95 98 100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              25  45 75                 GREEN FOXTAIL                                                                              50 65 80 90 95 100                                                                              80 90 90 100                                                                              100                                                                              100                                                                              100                                                                               0  30 60                 GIANT FOXTAIL                                                                              40 65 70 90 95 100                                                                              70 90 90 95 100                                                                              100                                                                              100                                                                               0  30 60                 FALL PANICUM 70 90 95 100                                                                              100                                                                              100                                                                              80 95 98 100                                                                              100                                                                              100                                                                              100                                                                               0  35 70                 LARGE CRABGRASS                                                                             0  0  0 30 70 80  0  0  0 30 40 60 70   0  0  0                 BARNYARDGRASS                                                                              90 100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              45  90 100                JOHNSONGRASS 100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              60  80 95                 G522 SORGHUM 100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              75  90 100                PURPLE NUTSEDGE                                                                            30 50 75 90 100                                                                              100                      0  35 45                 VELVETLEAF   20 45 75 85 95 100                                                                              40 60 60 60 90 100                                                                              100                                                                               0   0 35                 COCKLEBUR    50 85 100                                                                              100                                                                              100                                                                              100                                                                              40 40 40 90 100                                                                              100                                                                              100                                                                               0  30 40                 LADY SMARTWEED                                                                              0  0  0 25 50 70  0  0  0 30 50 80 80  0  30 75                 LAMBSQUARTER  0  0  0  0 35 50 30 30 30 60 40 50 70  0   0  0                 REDROOT PIGWEED                                                                            70 85 100                                                                              100                                                                              100                                                                              100                                                                              90 100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              35  70 100                IVY MORNINGLORY                                                                            50 85 100                                                                              100                                                                              100                                                                              100                                                                               0  0  0 20 30 40 70  0   0 20                 JIMSONWEED    0  0  0  0  0 35  0 20 20 30 40 40 50  0   0  0                 PERLITE CORN  0  0  0  0 20 30  0  0  0 10 10 20 60  0   0  0                 __________________________________________________________________________    POST                                                                                       CMPD 46     CMPD 60              CMPD 92                         RATE GM/HA   0016                                                                             0032                                                                             0064                                                                             0125                                                                             0002                                                                             0004                                                                             0008                                                                             0016                                                                             0032                                                                             0064                                                                             0125                                                                             0002                                                                             0004                                                                             0008                                                                              0016                                                                             0032               __________________________________________________________________________    SOIL TYPE    SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS                                                                              SAS SAS                                                                              SAS                G4646 CORN    0  0  0 30  0  0  0  0 30 60 85  0  0  0   0 20                 WILLMS SOYBEANS                                                                            90 100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              65 85 100 100                                                                              100                GREEN FOXTAIL                                                                              75 85 90 100                                                                              20 35 45 65 75 85 95 40 60 80  90 95                 GIANT FOXTAIL                                                                              75 85 90 100                                                                               0 25 40 60 75 90 100                                                                              40 65 80  100                                                                              100                FALL PANICUM 90 100                                                                              100                                                                              100                                                                              60 75 90 95 100                                                                              100                                                                              100                                                                               0 40 80  95 100                LARGE CRABGRASS                                                                             0 25 35 45  0  0  0 30 40 60 80  0  0  0  25 40                 BARNYARDGRASS                                                                              100                                                                              100                                                                              100                                                                              100                                                                              80 95 100                                                                              100                                                                              100                                                                              100                                                                              100                                                                               0 30 50  70 100                JOHNSONGRASS 100                                                                              100                                                                              100                                                                              100                                                                              95 100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              80 95 100 1                                                                                100                G522 SORGHUM 100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              85 95 100 100                                                                              100                PURPLE NUTSEDGE                                                                            60 80 95 100                                                                              30 50 65 75 100                                                                              100                                                                              100                                                                               0 35 60  90 100                VELVETLEAF   70 70 85 95 20 35 55 85 100                                                                              100                                                                              100                                                                               0 25 40  65 85                 COCKLEBUR    60 75 95 95 35 40 60 70 85 100                                                                              100                                                                              35 60 90  100                                                                              100                LADY SMARTWEED                                                                             85 95 100                                                                              100                                                                              20 30 40 60 80 100                                                                              100                                                                              25 40 50  60 70                 LAMBSQUARTER 30 40 55 65  0  0  0 35 60 90 95 40 65 85  95 100                REDROOT PIGWEED                                                                            100                                                                              100                                                                              100                                                                              100                                                                              60 75 100                                                                              100                                                                              100                                                                              100                                                                              100                                                                              75 95 100 100                                                                              100                IVY MORNINGLORY                                                                            40 60 70 80  0  0 20 40 65 80 95  0 30 55  70 85                 JIMSONWEED    0 25 40 60  0  0  0 20 40 65 85  0  0 20  40 60                 PERLITE CORN  0  0  0 25  0  0  0  0 25 50 70  0  0  0   0  0                 __________________________________________________________________________    POST                                                                                       CMPD 92                                                                              CMPD 96            CMPD 100                               RATE GM/HA   0064                                                                             0125                                                                              0002                                                                             0004                                                                             0008                                                                              0016                                                                             0032                                                                             0064                                                                             0002                                                                              0004                                                                             0008                                                                              0016                                                                             0032                                                                              0064                                                                             0125              __________________________________________________________________________    SOIL TYPE    SAS                                                                              SAS SAS                                                                              SAS                                                                              SAS SAS                                                                              SAS                                                                              SAS                                                                              SAS SAS                                                                              SAS SAS                                                                              SAS SAS                                                                              SAS               G4646 CORN   35 60   0 20 50  60 80 90  0   0  0   0  0   0 30                WILLMS SOYBEANS                                                                            100                                                                              100 90 90 98  98 100                                                                              100                                                                              65  75 90  100                                                                              100 100                                                                              100               GREEN FOXTAIL                                                                              100                                                                              100 50 60 70  70 90 98 50  65 80  95 100 100                                                                              100               GIANT FOXTAIL                                                                              100                                                                              100 40 50 60  70 98 100                                                                              45  60 80  90 95  100                                                                              100               FALL PANICUM 100                                                                              100                    50  65 80  95 95  100                                                                              100               LARGE CRABGRASS                                                                            50 80   0  0  0  20 40 50  0   0  0  30 40  50 80                BARNYARDGRASS                                                                              100                                                                              100 70 98 100 100                                                                              100                                                                              100                                                                              50  60 70  80 100 100                                                                              100               JOHNSONGRASS 100                                                                              100 60 98 100 100                                                                              100                                                                              100                                                                              95  100                                                                              100 100                                                                              100 100                                                                              100               G522 SORGHUM 100                                                                              100 80 90 98  100                                                                              100                                                                              100                                                                              100 100                                                                              100 100                                                                              100 100                                                                              100               PURPLE NUTSEDGE                                                                            100                                                                              100  0  0  0   0 30 70  0  20 40  65 85  90 95                VELVETLEAF   95 100  0  0 30  50 60 90  0  40 70  80 90  100                                                                              100               COCKLEBUR    100                                                                              100 30 70 80  90 100                                                                              100                                                                              45  95 100 100                                                                              100 100                                                                              100               LADY SMARTWEED                                                                             85 95  20 30 30  50 70 98  0  20 45  60 70  95 100               LAMBSQUARTER 100                                                                              100  0  0 30  30 30 30 30  40 60  80 90  100                                                                              100               REDROOT PIGWEED                                                                            100                                                                              100  0  0 40  40 80 90 65  90 100 100                                                                              100 100                                                                              100               IVY MORNINGLORY                                                                            95 100  0 30 30  30 40 50 30  70 85  100                                                                              100 100                                                                              100               JIMSONWEED   70 85  40 60 60  60 100                                                                              100                                                                               0   0  0   0 25  45 70                PERLITE CORN 20 40  20 20 30  60 60 90  0   0  0   0  0   0 20                __________________________________________________________________________

TEST D

Potatoes (Solanum tuberosum), cult. `Green Mountain`) were grown inMetro 350 medium in 20 cm plastic pots. Potatoes were 17 days old attime of spraying. Barnyardgrass (Echinochloa crus-galli), johnsongrass(Sorghum halepense), giant foxtail (Setaria faberii), crabgrass(Digitaria sanguinalis), purple nutsedge (Cyperus rotundus), jimsonweed(Datura stramonium), velvetleaf (Abutilon theophrasti), cocklebur(Xanthium pensylvanicum), and morningglory (Ipomoea hederacea) weregrown in Sassafras sandy loam (pH 6.5, 1% organic matter) inplastic-lined 25 cm pots. These plants were 9 days old at the time ofspraying.

Compound 21 was sprayed at 62, 16, 4, and 1 g/ha. The compound wassprayed at each rate on one pot containing potato plants and at the sametime on one pot containing the remaining species. Compound 21 wasdissolved in a non-phytotoxic solvent. The solvent was sprayed at 374l/ha. Plants were maintained in a greenhouse and were evaluated 11 daysafter spraying.

All sprayed plants were evaluated for injury as compared to controlplants. Injury was measured visually using a 0 to 100% scale where 0=noeffect and 100=complete control. Results are shown in Table D.

                  TABLE D                                                         ______________________________________                                        Compound 21                                                                               Rate (g/ha)                                                       Species       62     16         4    1                                        ______________________________________                                        Potato         0      0          0    0                                       Barnyardgrass 100    100        70   30                                       Johnsongrass  100    100        100  60                                       Giant foxtail 100    100        90   60                                       Crabgrass     90     85         60   50                                       Purple nutsedge                                                                             90     90         80   30                                       Jimsonweed    80     60         40   20                                       Velvetleaf    100    95         50   20                                       Cocklebur     90     50         30    0                                       Morningglory  90     70         40   20                                       ______________________________________                                    

TEST E

Tomatoes (Lycopersicon esculentum cult. `Rutgers`) and peppers (Capsicumfrutescens cult. `Yolo`) were grown in Metro 350 medium in 10 cm plasticpots. Tomatoes and peppers were 19 days old at time of spraying. Purplenutsedge (Cyperus rotundus), crabgrass (Digitaria sanguinalis),sicklepod (Cassia tora), prickley sida (Sida spinosa), jimsonweed(Datura stramonium), velvetleaf (Abutilon theophrasti), lambsquarter(Chenopodium album), green foxtail (Setaria viridis), cocklebur(Xanthium pensylvanicum), morningglory (Ipomoea hederacea), johnsongrass(Sorghum halepense), barnyardgrass (Echinochloa crus-galli), giantfoxtail (Setaria faberii), wild buckwheat (Polygonum convolvulus), downybrome (Bromus tectorum), wild oat (Avena fatua), chickweed (Stellariaspp.), and blackgrass (Alopecurus myosuroides), were grown in Sassafrassandy loam (pH 6.5, 1% organic matter) in plastic-lined 25 cm pots.These plants were 7 to 11 days old at the time of spraying.

Compound 21 was sprayed at 62, 16, 4, and 1g/ha. The compound wassprayed at each rate on one pot containing tomatoes, one pot containingpeppers, and on three pots containing the remaining species. Thecompound was dissolved in a non-phytotoxic solvent, and the solvent wassprayed at 374 l/ha. Plants were maintained in a greenhouse and wereevaluated 16 days after spraying.

All sprayed plants were evaluated for injury as compared to controlplants. Injury was measured visually using a 0 to 100% scale where 0=noeffect and 100=complete control. Results are shown in Table E.

                  TABLE E                                                         ______________________________________                                        Compound 21                                                                               Rate (g/ha)                                                       Species       62     16         4    1                                        ______________________________________                                        Tomatoes       10     0          0    0                                       Peppers        80     70        50   30                                       Nutsedge      100    100        30    0                                       Crabgrass      90     80        50   30                                       Sicklepod     100    100        90   40                                       Prickley sida 100    100        50   20                                       Jimsonweed    100     50        10    0                                       Velvetleaf    100    100        70   50                                       Lambsquarter   60     50        40    0                                       Green foxtail 100    100        100  50                                       Cocklebur     100     80        50   20                                       Morningglory   90     85        50   20                                       Johnsongrass  100    100        100  50                                       Barnyardgrass 100    100        100  40                                       Giant foxtail 100    100        90   40                                       Wild buckwheat                                                                              100     90        90   40                                       Downy brome   100    100        80   20                                       Wild oats     100     70        30   20                                       Chickweed     100    100        90   90                                       Blackgrass    100    100        100  70                                       ______________________________________                                    

What is claimed is:
 1. A compound of formula I ##STR58## wherein J is##STR59## W is O; R is H or CH₃ ;R₁ is R_(f) or R_(g) ; R_(f) is C₁haloalkyl, halogen or OCH₃ ; R_(g) is C₁ -C₂ haloalkyl or W₂ R₁₁ ; R₂ isCN, CO₂ R₉, CO₂ R'₉ ; R₉ is CH₂ CH₂ R₁₀, CH₂ CF₃, C₃ -C₄ haloalkyl, C₃-C₄ alkynyl, C₂ -C₄ alkylthioalkyl, C₃ -C₅ cycloalkyl or C₄ -C₇cycloalkylalkyl; R'₉ is C₁ -C₄ alkyl, C₃ -alkenyl, CH₂ CH₂ Cl, CH₂ CH₂Br, CH₂ CH₂ OCH₃ or CH₂ CH₂ OC₂ H₅ ; R₁₀ is OH, F, CN, OSO₂ (C₁ -C₃alkyl) or OSO₂ (C₁ -C₃ haloalkyl); R₁₁ is C_(alkyl) or C₁ -C₃ haloalkyl;and A is ##STR60## X is C₁ -C₂ alkyl, C₁ -C₂ alkoxy, Cl, F, Br, I, CH₂F, CF₃, OCH₂ CH₂ F, OCH₂ CHF₂, OCH₂ CF₃, CH₂ Cl or CH₂ Br; Y is H, C₁-C₂ alkyl, C₁ -C₂ alkoxy, CH₂ OCH₃, CH₂ OCH₂ CH₃, NHCH₃, N(OCH₃)CH₃,N(CH₃)₂, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ CCH, OCH₂ CH₂ OCH₃, C(O)R_(a),cyclopropyl, C.tbd.CH or C.tbd.CCH₃ ; R_(a) is H or CH₃ ; and Z isCH;and their agriculturally suitable salts; provided that 1) when X ishalogen, then Y is OCH₃, OC₂ H₅, NHCH₃, N(CH₃)₂ or N(OCH₃)CH₃ ; and 2)when R₂ is CO₂ R'₉ then R₁ is R_(g) and when R₂ is other than CO₂ R'₉,then R₁ is R_(f).
 2. A composition suitable for controlling the growthof undesired vegetation which comprises an effective amount of acompound of claim 1 and at least one of the following: surfactant, solidinert diluent or liquid inert diluent and mixtures of the foregoing. 3.A method for controlling the growth of undesired vegetation whichcomprises applying to the locus to be protected an effective amount of acompound of claim 1.